JP2024525897A - 変形性関節症の治療におけるｎｌｒｐ３阻害剤の投与計画 - Google Patents
変形性関節症の治療におけるｎｌｒｐ３阻害剤の投与計画 Download PDFInfo
- Publication number
- JP2024525897A JP2024525897A JP2024503567A JP2024503567A JP2024525897A JP 2024525897 A JP2024525897 A JP 2024525897A JP 2024503567 A JP2024503567 A JP 2024503567A JP 2024503567 A JP2024503567 A JP 2024503567A JP 2024525897 A JP2024525897 A JP 2024525897A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- use according
- subject
- nlrp3 inhibitor
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163224890P | 2021-07-23 | 2021-07-23 | |
| US63/224,890 | 2021-07-23 | ||
| PCT/IB2022/056695 WO2023002399A1 (en) | 2021-07-23 | 2022-07-20 | Dosing regimen for an nlrp3 inhibitor in the treatment of osteoarthritis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024525897A true JP2024525897A (ja) | 2024-07-12 |
| JP2024525897A5 JP2024525897A5 (https=) | 2025-07-28 |
Family
ID=82846336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024503567A Pending JP2024525897A (ja) | 2021-07-23 | 2022-07-20 | 変形性関節症の治療におけるｎｌｒｐ３阻害剤の投与計画 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250082611A1 (https=) |
| EP (1) | EP4373489A1 (https=) |
| JP (1) | JP2024525897A (https=) |
| KR (1) | KR20240038995A (https=) |
| CN (1) | CN117693340A (https=) |
| CA (1) | CA3224774A1 (https=) |
| IL (1) | IL309085A (https=) |
| WO (1) | WO2023002399A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS65962B1 (sr) | 2020-05-08 | 2024-10-31 | Halia Therapeutics Inc | Inhibitori nek7 kinaze |
| WO2025153532A1 (en) | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS65492B1 (sr) | 2017-07-24 | 2024-05-31 | Novartis Ag | Jedinjenja i kompozicije za lečenje stanja povezanih sa aktivnošću nlrp |
| CN112654350A (zh) * | 2018-07-03 | 2021-04-13 | 诺华股份有限公司 | 使用nlrp3拮抗剂治疗对tnf抑制剂有抗性的受试者或针对所述患者选择治疗的方法 |
| GB201916237D0 (en) * | 2019-11-07 | 2019-12-25 | Inflazome Ltd | Novel treatment |
-
2022
- 2022-07-20 IL IL309085A patent/IL309085A/en unknown
- 2022-07-20 KR KR1020247005666A patent/KR20240038995A/ko active Pending
- 2022-07-20 CN CN202280049591.4A patent/CN117693340A/zh active Pending
- 2022-07-20 EP EP22751844.6A patent/EP4373489A1/en active Pending
- 2022-07-20 JP JP2024503567A patent/JP2024525897A/ja active Pending
- 2022-07-20 US US18/580,781 patent/US20250082611A1/en active Pending
- 2022-07-20 WO PCT/IB2022/056695 patent/WO2023002399A1/en not_active Ceased
- 2022-07-20 CA CA3224774A patent/CA3224774A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023002399A1 (en) | 2023-01-26 |
| KR20240038995A (ko) | 2024-03-26 |
| CA3224774A1 (en) | 2023-01-26 |
| EP4373489A1 (en) | 2024-05-29 |
| IL309085A (en) | 2024-02-01 |
| CN117693340A (zh) | 2024-03-12 |
| US20250082611A1 (en) | 2025-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20250717 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20250717 |