JP2024525552A5 - - Google Patents

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Publication number
JP2024525552A5
JP2024525552A5 JP2024500191A JP2024500191A JP2024525552A5 JP 2024525552 A5 JP2024525552 A5 JP 2024525552A5 JP 2024500191 A JP2024500191 A JP 2024500191A JP 2024500191 A JP2024500191 A JP 2024500191A JP 2024525552 A5 JP2024525552 A5 JP 2024525552A5
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JP
Japan
Prior art keywords
optionally substituted
group
substituted
alkyl
solid support
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024500191A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525552A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/036538 external-priority patent/WO2023283434A1/en
Publication of JP2024525552A publication Critical patent/JP2024525552A/ja
Publication of JP2024525552A5 publication Critical patent/JP2024525552A5/ja
Pending legal-status Critical Current

Links

JP2024500191A 2021-07-09 2022-07-08 アミノオキシクリックケミストリー（ａｏｃｃ）：多用途バイオコンジュゲーションアプローチ Pending JP2024525552A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163220333P 2021-07-09 2021-07-09
US63/220,333 2021-07-09
US202163247067P 2021-09-22 2021-09-22
US63/247,067 2021-09-22
US202263324907P 2022-03-29 2022-03-29
US63/324,907 2022-03-29
PCT/US2022/036538 WO2023283434A1 (en) 2021-07-09 2022-07-08 Aminooxy click chemistry (aocc): a versatile bioconjugation approach

Publications (2)

Publication Number Publication Date
JP2024525552A JP2024525552A (ja) 2024-07-12
JP2024525552A5 true JP2024525552A5 (https=) 2025-07-11

Family

ID=84801021

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024500191A Pending JP2024525552A (ja) 2021-07-09 2022-07-08 アミノオキシクリックケミストリー（ａｏｃｃ）：多用途バイオコンジュゲーションアプローチ

Country Status (4)

Country Link
US (1) US20250304613A1 (https=)
EP (1) EP4367125A4 (https=)
JP (1) JP2024525552A (https=)
WO (1) WO2023283434A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116854754B (zh) * 2023-09-01 2023-12-12 北京悦康科创医药科技股份有限公司 一种含有核糖环或其衍生结构的GalNAc化合物及其寡核苷酸缀合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6639062B2 (en) * 1997-02-14 2003-10-28 Isis Pharmaceuticals, Inc. Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefrom
US7291603B2 (en) * 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations
AU2005330637B2 (en) * 2004-08-04 2012-09-20 Alnylam Pharmaceuticals, Inc. Oligonucleotides comprising a ligand tethered to a modified or non-natural nucleobase
US9290534B2 (en) * 2008-04-04 2016-03-22 Ionis Pharmaceuticals, Inc. Oligomeric compounds having at least one neutrally linked terminal bicyclic nucleoside
EP2694524B1 (en) * 2011-04-04 2016-05-18 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services 2'-o-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides
CN111527206A (zh) * 2017-11-13 2020-08-11 赛伦斯治疗有限责任公司 用于抑制靶标基因表达的包含二硫代磷酸酯键的核酸
EP3912628A1 (en) * 2020-05-20 2021-11-24 Institut de Recherche en Semiochimie et Ethologie Appliquée Nucleoside analogues to inhibit the main protease of a coronavirus

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