JP2022533419A5 - - Google Patents
Info
- Publication number
- JP2022533419A5 JP2022533419A5 JP2021569112A JP2021569112A JP2022533419A5 JP 2022533419 A5 JP2022533419 A5 JP 2022533419A5 JP 2021569112 A JP2021569112 A JP 2021569112A JP 2021569112 A JP2021569112 A JP 2021569112A JP 2022533419 A5 JP2022533419 A5 JP 2022533419A5
- Authority
- JP
- Japan
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910430586 | 2019-05-22 | ||
| CN201910430586.8 | 2019-05-22 | ||
| PCT/CN2020/091485 WO2020233651A1 (zh) | 2019-05-22 | 2020-05-21 | 核酸、药物组合物与缀合物及制备方法和用途 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022533419A JP2022533419A (ja) | 2022-07-22 |
| JPWO2020233651A5 JPWO2020233651A5 (https=) | 2023-05-30 |
| JP2022533419A5 true JP2022533419A5 (https=) | 2023-05-30 |
| JP7606758B2 JP7606758B2 (ja) | 2024-12-26 |
Family
ID=73458360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569112A Active JP7606758B2 (ja) | 2019-05-22 | 2020-05-21 | 核酸、薬物組成物及び複合体ならびに調製方法と使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240200076A1 (https=) |
| EP (1) | EP3974533A4 (https=) |
| JP (1) | JP7606758B2 (https=) |
| CN (2) | CN118340793A (https=) |
| TW (1) | TWI863999B (https=) |
| WO (1) | WO2020233651A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12496347B2 (en) | 2018-12-28 | 2025-12-16 | Suzhou Ribo Life Science Co., Ltd. | Nucleic acid, composition and conjugate containing nucleic acid, preparation method therefor and use thereof |
| AU2020280438B2 (en) | 2019-05-22 | 2025-03-06 | Suzhou Ribo Life Science Co., Ltd. | Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use |
| JP7610268B2 (ja) | 2019-05-22 | 2025-01-08 | スーチョウ リボ ライフ サイエンス カンパニー、リミテッド | 核酸、薬物組成物及び複合体ならびに調製方法と使用 |
| WO2020233680A1 (zh) | 2019-05-22 | 2020-11-26 | 苏州瑞博生物技术股份有限公司 | 核酸、药物组合物与缀合物及制备方法和用途 |
| EP3978609A4 (en) | 2019-05-24 | 2024-02-07 | Suzhou Ribo Life Science Co., Ltd. | Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use |
| CN114686482B (zh) * | 2020-12-29 | 2024-05-17 | 苏州瑞博生物技术股份有限公司 | 一种核酸、含有该核酸的药物组合物与siRNA缀合物及制备方法和用途 |
| CN113073098B (zh) * | 2021-02-20 | 2024-08-20 | 北京理工大学 | 抑制BACE1基因表达的siRNA修饰物及其应用 |
| WO2024240212A1 (zh) * | 2023-05-24 | 2024-11-28 | 云合智药（苏州）生物科技有限公司 | 用于抑制angptl3表达的rnai剂及其应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040259247A1 (en) * | 2000-12-01 | 2004-12-23 | Thomas Tuschl | Rna interference mediating small rna molecules |
| WO2009082607A2 (en) | 2007-12-04 | 2009-07-02 | Alnylam Pharmaceuticals, Inc. | Targeting lipids |
| US8236943B2 (en) * | 2009-07-01 | 2012-08-07 | Protiva Biotherapeutics, Inc. | Compositions and methods for silencing apolipoprotein B |
| US8691580B2 (en) * | 2010-04-09 | 2014-04-08 | Merck Sharp & Dohme Corp. | Single chemical entities and methods for delivery of oligonucleotides |
| US20120136073A1 (en) * | 2010-11-15 | 2012-05-31 | Life Technologies Corporation | Amine-Containing Transfection Reagents and methods for making and using same |
| KR101870915B1 (ko) * | 2011-04-08 | 2018-06-25 | 유니버시티 오브 레스터 | Ｍａｓｐ-2 의존적 보체 활성화와 관련된 질병을 치료하는 방법 |
| AU2013299717B2 (en) | 2012-08-06 | 2018-06-28 | Alnylam Pharmaceuticals, Inc. | Carbohydrate conjugated RNA agents and process for their preparation |
| DK2991656T3 (da) | 2013-05-01 | 2020-03-23 | Ionis Pharmaceuticals Inc | Sammensætninger og fremgangsmåder til modulering af apolipoprotein c-iii-ekspression |
| JP2016528890A (ja) * | 2013-07-09 | 2016-09-23 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ＣＲＩＳＰＲ／Ｃａｓ系を用いるゲノム編集の治療用の使用 |
| JP6702862B2 (ja) | 2013-07-11 | 2020-06-03 | アルニラム ファーマスーティカルズ インコーポレイテッドＡｌｎｙｌａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | オリゴヌクレオチド−リガンドコンジュゲートおよびそれらの調製方法 |
| US10607717B2 (en) * | 2013-11-06 | 2020-03-31 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for subtyping lymphoma types by means of expression profiling |
| CN110945130B (zh) * | 2017-12-01 | 2024-04-09 | 苏州瑞博生物技术股份有限公司 | 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途 |
| CA3083968C (en) * | 2017-12-01 | 2024-04-23 | Suzhou Ribo Life Science Co., Ltd. | Double-stranded oligonucleotide, composition and conjugate comprising double-stranded oligonucleotide, preparation method thereof and use thereof |
| US20240309378A1 (en) * | 2021-07-16 | 2024-09-19 | Suzhou Ribo Life Science Co., Ltd. | Double-stranded oligonucleotide, composition and conjugate containing double-stranded oligonucleotide, and preparation methods and uses |
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2020
- 2020-05-21 WO PCT/CN2020/091485 patent/WO2020233651A1/zh not_active Ceased
- 2020-05-21 JP JP2021569112A patent/JP7606758B2/ja active Active
- 2020-05-21 EP EP20810635.1A patent/EP3974533A4/en not_active Withdrawn
- 2020-05-21 CN CN202410318986.0A patent/CN118340793A/zh active Pending
- 2020-05-21 CN CN202080007348.7A patent/CN113614230B/zh active Active
- 2020-05-21 US US17/595,620 patent/US20240200076A1/en not_active Abandoned
- 2020-05-21 TW TW109116934A patent/TWI863999B/zh active