JP2022534069A5 - - Google Patents

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Publication number
JP2022534069A5
JP2022534069A5 JP2021569555A JP2021569555A JP2022534069A5 JP 2022534069 A5 JP2022534069 A5 JP 2022534069A5 JP 2021569555 A JP2021569555 A JP 2021569555A JP 2021569555 A JP2021569555 A JP 2021569555A JP 2022534069 A5 JP2022534069 A5 JP 2022534069A5
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JP
Japan
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JP2021569555A
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Japanese (ja)
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JP7614650B2 (ja
JPWO2020238758A5 (https=
JP2022534069A (ja
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JP2021569555A 2019-05-24 2020-05-21 核酸、薬物組成物及び複合体並びに調製方法と使用 Active JP7614650B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201910441597 2019-05-24
CN201910441597.6 2019-05-24
PCT/CN2020/091606 WO2020238758A1 (zh) 2019-05-24 2020-05-21 核酸、药物组合物与缀合物及制备方法和用途

Publications (4)

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JP2022534069A JP2022534069A (ja) 2022-07-27
JPWO2020238758A5 JPWO2020238758A5 (https=) 2023-05-29
JP2022534069A5 true JP2022534069A5 (https=) 2023-05-29
JP7614650B2 JP7614650B2 (ja) 2025-01-16

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JP2021569555A Active JP7614650B2 (ja) 2019-05-24 2020-05-21 核酸、薬物組成物及び複合体並びに調製方法と使用

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US (1) US20220315929A1 (https=)
EP (1) EP3992290A4 (https=)
JP (1) JP7614650B2 (https=)
CN (1) CN113891939B (https=)
WO (1) WO2020238758A1 (https=)

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Publication number Priority date Publication date Assignee Title
WO2019105435A1 (zh) 2017-12-01 2019-06-06 苏州瑞博生物技术有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
JP7365052B2 (ja) 2017-12-01 2023-10-19 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用
CN110945130B (zh) 2017-12-01 2024-04-09 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
US11918600B2 (en) 2018-08-21 2024-03-05 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition and conjugate containing nucleic acid, and use thereof
US12496347B2 (en) 2018-12-28 2025-12-16 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, composition and conjugate containing nucleic acid, preparation method therefor and use thereof
WO2020233680A1 (zh) 2019-05-22 2020-11-26 苏州瑞博生物技术股份有限公司 核酸、药物组合物与缀合物及制备方法和用途
JP7610268B2 (ja) 2019-05-22 2025-01-08 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、薬物組成物及び複合体ならびに調製方法と使用
AU2020280438B2 (en) * 2019-05-22 2025-03-06 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
EP3978609A4 (en) 2019-05-24 2024-02-07 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
EP4273245A4 (en) * 2020-12-29 2024-12-11 Suzhou Ribo Life Science Co., Ltd. NUCLEIC ACID, PHARMACEUTICAL COMPOSITION AND SIRNA CONJUGATE WITH THE NUCLEIC ACID, MANUFACTURING PROCESS THEREOF AND USE THEREOF
MX2024004011A (es) 2021-10-01 2024-07-01 Adarx Pharmaceuticals Inc Composiciones moduladoras de precalicreína y métodos de uso de estas.
TW202346586A (zh) * 2022-01-28 2023-12-01 大陸商上海舶望製藥有限公司 用於抑制前激肽釋放酶(pkk)蛋白表達的組合物和方法
CN120209051A (zh) * 2023-12-27 2025-06-27 武汉人福创新药物研发中心有限公司 用于递送的靶向化合物及其用途

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EP2305812A3 (en) * 2002-11-14 2012-06-06 Dharmacon, Inc. Fuctional and hyperfunctional sirna
EP1752536A4 (en) * 2004-05-11 2008-04-16 Alphagen Co Ltd POLYNUCLEOTIDE CAUSING RNA INTERFERENCE AND METHOD OF REGULATING GENE EXPRESSION WITH THE USE OF THE SAME
WO2009082607A2 (en) 2007-12-04 2009-07-02 Alnylam Pharmaceuticals, Inc. Targeting lipids
US20120136073A1 (en) 2010-11-15 2012-05-31 Life Technologies Corporation Amine-Containing Transfection Reagents and methods for making and using same
CA2823776A1 (en) * 2011-01-06 2012-07-12 Dyax Corp. Plasma kallikrein binding proteins
AU2013299717B2 (en) 2012-08-06 2018-06-28 Alnylam Pharmaceuticals, Inc. Carbohydrate conjugated RNA agents and process for their preparation
DK2991656T3 (da) 2013-05-01 2020-03-23 Ionis Pharmaceuticals Inc Sammensætninger og fremgangsmåder til modulering af apolipoprotein c-iii-ekspression
JP6702862B2 (ja) 2013-07-11 2020-06-03 アルニラム ファーマスーティカルズ インコーポレイテッドAlnylam Pharmaceuticals, Inc. オリゴヌクレオチド−リガンドコンジュゲートおよびそれらの調製方法
KR102365486B1 (ko) * 2013-08-28 2022-02-18 아이오니스 파마수티컬즈, 인코포레이티드 프리칼리크레인 (pkk) 발현의 조절
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KR102827366B1 (ko) * 2015-05-06 2025-07-03 알닐람 파마슈티칼스 인코포레이티드 인자 XII(하게만 인자)(F12), 칼리크레인 B, 혈장(플레처 인자) 1(KLKB1) 및 키니노겐 1(KNG1) iRNA 조성물 및 그의 이용 방법

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