JP2024525142A5 - - Google Patents
Info
- Publication number
- JP2024525142A5 JP2024525142A5 JP2023576326A JP2023576326A JP2024525142A5 JP 2024525142 A5 JP2024525142 A5 JP 2024525142A5 JP 2023576326 A JP2023576326 A JP 2023576326A JP 2023576326 A JP2023576326 A JP 2023576326A JP 2024525142 A5 JP2024525142 A5 JP 2024525142A5
- Authority
- JP
- Japan
- Prior art keywords
- column
- particles
- chromatography medium
- raav
- complete
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163209680P | 2021-06-11 | 2021-06-11 | |
| US63/209,680 | 2021-06-11 | ||
| US202263366094P | 2022-06-09 | 2022-06-09 | |
| US63/366,094 | 2022-06-09 | ||
| PCT/US2022/072859 WO2022261663A1 (en) | 2021-06-11 | 2022-06-10 | Aav vector column purification methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024525142A JP2024525142A (ja) | 2024-07-10 |
| JP2024525142A5 true JP2024525142A5 (enExample) | 2025-06-17 |
Family
ID=84426294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023576326A Pending JP2024525142A (ja) | 2021-06-11 | 2022-06-10 | Ａａｖベクターカラム精製方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20240271159A1 (enExample) |
| EP (1) | EP4351755A4 (enExample) |
| JP (1) | JP2024525142A (enExample) |
| KR (1) | KR20240021231A (enExample) |
| AU (1) | AU2022289035A1 (enExample) |
| BR (1) | BR112023025999A2 (enExample) |
| CA (1) | CA3221540A1 (enExample) |
| CL (1) | CL2023003646A1 (enExample) |
| CO (1) | CO2023018191A2 (enExample) |
| IL (1) | IL309070A (enExample) |
| MX (1) | MX2023014809A (enExample) |
| PE (1) | PE20240359A1 (enExample) |
| WO (1) | WO2022261663A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2025528182A (ja) * | 2022-08-12 | 2025-08-26 | ウルトラジェニックス ファーマシューティカル インコーポレイテッド | 完全な組換えアデノ関連性ウイルス粒子から空の粒子を分離するための新規な陰イオン交換クロマトグラフィーの方法 |
| EP4670812A1 (en) * | 2024-06-27 | 2025-12-31 | Sartorius Stedim Biotech GmbH | CONTINUOUS POLISHING OF VIRAL CAPSIDES |
| WO2026064763A1 (en) * | 2024-09-23 | 2026-03-26 | Regeneron Pharmaceuticals, Inc. | Partitioning anion exchange chromatography for purification of recombinant adeno-associated virus (raav) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7261544B2 (en) * | 2003-05-21 | 2007-08-28 | Genzyme Corporation | Methods for producing preparations of recombinant AAV virions substantially free of empty capsids |
| US20120093775A1 (en) * | 2009-03-27 | 2012-04-19 | Proyecto De Biomedicina Cima, S.L. | Methods and compositions for the treatment of cirrhosis and liver fibrosis |
| PE20200737A1 (es) * | 2017-06-30 | 2020-07-23 | Spark Therapeutics Inc | Metodos de purificacion de columna de vector aav |
| WO2023077086A1 (en) * | 2021-10-29 | 2023-05-04 | Homology Medicines, Inc. | Methods and compositions for the purification of adeno-associated virus |
| CN120283059A (zh) * | 2022-10-11 | 2025-07-08 | 梅里特斯英国第二有限公司 | 纯化aav衣壳的色谱方法 |
-
2022
- 2022-06-10 WO PCT/US2022/072859 patent/WO2022261663A1/en not_active Ceased
- 2022-06-10 MX MX2023014809A patent/MX2023014809A/es unknown
- 2022-06-10 JP JP2023576326A patent/JP2024525142A/ja active Pending
- 2022-06-10 US US18/568,530 patent/US20240271159A1/en active Pending
- 2022-06-10 AU AU2022289035A patent/AU2022289035A1/en active Pending
- 2022-06-10 PE PE2023003271A patent/PE20240359A1/es unknown
- 2022-06-10 CA CA3221540A patent/CA3221540A1/en active Pending
- 2022-06-10 BR BR112023025999A patent/BR112023025999A2/pt unknown
- 2022-06-10 IL IL309070A patent/IL309070A/en unknown
- 2022-06-10 EP EP22821261.9A patent/EP4351755A4/en active Pending
- 2022-06-10 KR KR1020247000822A patent/KR20240021231A/ko active Pending
-
2023
- 2023-12-05 CL CL2023003646A patent/CL2023003646A1/es unknown
- 2023-12-21 CO CONC2023/0018191A patent/CO2023018191A2/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024525142A5 (enExample) | ||
| JP2021526829A5 (enExample) | ||
| US12351832B2 (en) | Recombinant adeno-associated virus particle purification with multiple-step anion exchange chromatography | |
| Kaludov et al. | Scalable purification of adeno-associated virus type 2, 4, or 5 using ion-exchange chromatography | |
| EP3256574B1 (en) | Recombinant adeno-associated virus particle purification comprising an affinity purification step | |
| US7419817B2 (en) | Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography | |
| ES2881050T3 (es) | Métodos mejorados para la purificación de vectores de AAV recombinantes | |
| JP2020533959A5 (enExample) | ||
| KR102405250B1 (ko) | 컬럼-기반 완전히 확장 가능한 rAAV 제조 공정 | |
| CA3146831A1 (en) | Separation and quantification of empty and full viral capsid particles | |
| JP7815128B2 (ja) | フルａａｖカプシドから空のａａｖカプシドを分離又は枯渇させる方法 | |
| JP2023515692A5 (enExample) | ||
| US20250066743A1 (en) | Methods and compositions for purifying adeno associated virus particles | |
| EP4150101A2 (en) | Methods and compositions for purifying adeno associated virus particles or adenoviruses | |
| JP2025535118A (ja) | Ａａｖカプシドの精製のためのクロマトグラフィー方法 | |
| JP2024511409A5 (enExample) | ||
| RU2023135618A (ru) | Методы колоночной очистки вектора aav | |
| WO2024015369A1 (en) | Methods and compositions for the enrichment of nucleic acid containing aav capsids | |
| Chen et al. | Tuning Mobile Phase Properties to Improve Empty Full Particle Separation in Adeno-associated Virus by Anion Exchange Chromatography | |
| WO2025027058A1 (en) | Polishing for aav particles using anion exchange chromatography with improved elution system | |
| WO2025073922A1 (en) | Enhanced chromatographic separations of components in a mixture by employing chaotropic elution | |
| KR20260019635A (ko) | 완전 충전 아데노 관련 바이러스 (aav) 캡시드의 향상된 분리 방법 | |
| Subramanian et al. | Enrichment of full AAV capsids by preparative strong anion exchange chromatography | |
| KR20250172635A (ko) | 크로마토그래피 물질, 그의 용도, 및 아데노-연관 캡시드를 분리하는 방법 | |
| EP4670812A1 (en) | CONTINUOUS POLISHING OF VIRAL CAPSIDES |