JP2024511409A5 - - Google Patents

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Publication number
JP2024511409A5
JP2024511409A5 JP2023558125A JP2023558125A JP2024511409A5 JP 2024511409 A5 JP2024511409 A5 JP 2024511409A5 JP 2023558125 A JP2023558125 A JP 2023558125A JP 2023558125 A JP2023558125 A JP 2023558125A JP 2024511409 A5 JP2024511409 A5 JP 2024511409A5
Authority
JP
Japan
Prior art keywords
capsid
aav
itr
approximately
chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023558125A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024511409A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/071245 external-priority patent/WO2022204670A2/en
Publication of JP2024511409A publication Critical patent/JP2024511409A/ja
Publication of JP2024511409A5 publication Critical patent/JP2024511409A5/ja
Pending legal-status Critical Current

Links

JP2023558125A 2021-03-22 2022-03-21 空および完全aavキャプシドのサイズ排除クロマトグラフィー解析 Pending JP2024511409A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163164206P 2021-03-22 2021-03-22
US63/164,206 2021-03-22
PCT/US2022/071245 WO2022204670A2 (en) 2021-03-22 2022-03-21 Size exclusion chromatography analysis of empty and full aav capsids

Publications (2)

Publication Number Publication Date
JP2024511409A JP2024511409A (ja) 2024-03-13
JP2024511409A5 true JP2024511409A5 (enExample) 2025-04-14

Family

ID=81580107

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023558125A Pending JP2024511409A (ja) 2021-03-22 2022-03-21 空および完全aavキャプシドのサイズ排除クロマトグラフィー解析

Country Status (5)

Country Link
US (1) US20240159718A1 (enExample)
EP (1) EP4314303A2 (enExample)
JP (1) JP2024511409A (enExample)
CN (1) CN117460832A (enExample)
WO (1) WO2022204670A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024137017A1 (en) * 2022-12-22 2024-06-27 Lonza Houston, Inc. Methods for characterizing lentiviruses
US12434218B2 (en) 2023-11-28 2025-10-07 Phenomenex, Inc. Pore structure for separation of adeno-associated viruses (AAVS) from their aggregates

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001650A (en) 1995-08-03 1999-12-14 Avigen, Inc. High-efficiency wild-type-free AAV helper functions
US5622856A (en) 1995-08-03 1997-04-22 Avigen High efficiency helper system for AAV vector production
US6027931A (en) 1995-08-03 2000-02-22 Avigen, Inc. High-efficiency AA V helper functions
US6989264B2 (en) 1997-09-05 2006-01-24 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
US6566118B1 (en) 1997-09-05 2003-05-20 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
CA2379166C (en) 1999-08-09 2013-03-26 Targeted Genetics Corporation Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms instrastrand base pairs
ATE318923T1 (de) 2000-06-01 2006-03-15 Univ North Carolina Doppelsträngige parvovirus-vektoren
US6723551B2 (en) 2001-11-09 2004-04-20 The United States Of America As Represented By The Department Of Health And Human Services Production of adeno-associated virus in insect cells
MX359371B (es) 2001-11-13 2018-09-25 Univ Pennsylvania Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo.
US7261544B2 (en) 2003-05-21 2007-08-28 Genzyme Corporation Methods for producing preparations of recombinant AAV virions substantially free of empty capsids
US20050101025A1 (en) * 2003-11-12 2005-05-12 Ho Winston Z. Apparatus for proteins and nucleic acids analysis
US7765583B2 (en) 2005-02-28 2010-07-27 France Telecom System and method for managing virtual user domains
WO2006119432A2 (en) 2005-04-29 2006-11-09 The Government Of The U.S.A., As Rep. By The Sec., Dept. Of Health & Human Services Isolation, cloning and characterization of new adeno-associated virus (aav) serotypes
KR20180000341A (ko) 2009-06-16 2018-01-02 젠자임 코포레이션 재조합 aav 벡터에 대한 개선된 정제 방법
EA201791630A1 (ru) * 2015-01-20 2018-04-30 Джензим Корпорейшн Аналитическое ультрацентрифугирование для определения характеристик рекомбинантных вирусных частиц
WO2019212922A1 (en) * 2018-04-29 2019-11-07 Regenxbio Inc. Systems and methods of spectrophotometry for the determination of genome content, capsid content and full/empty ratios of adeno-associated virus particles

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