JP2024522106A5 - - Google Patents

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Publication number
JP2024522106A5
JP2024522106A5 JP2023573112A JP2023573112A JP2024522106A5 JP 2024522106 A5 JP2024522106 A5 JP 2024522106A5 JP 2023573112 A JP2023573112 A JP 2023573112A JP 2023573112 A JP2023573112 A JP 2023573112A JP 2024522106 A5 JP2024522106 A5 JP 2024522106A5
Authority
JP
Japan
Prior art keywords
nucleotide
dsrna agent
modified nucleotide
nucleotides
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023573112A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024522106A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/031337 external-priority patent/WO2022251629A2/en
Publication of JP2024522106A publication Critical patent/JP2024522106A/ja
Publication of JP2024522106A5 publication Critical patent/JP2024522106A5/ja
Pending legal-status Critical Current

Links

JP2023573112A 2021-05-27 2022-05-27 炭酸脱水酵素2発現をサイレンシングするための組成物および方法 Pending JP2024522106A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163194073P 2021-05-27 2021-05-27
US63/194,073 2021-05-27
US202163289319P 2021-12-14 2021-12-14
US63/289,319 2021-12-14
PCT/US2022/031337 WO2022251629A2 (en) 2021-05-27 2022-05-27 Compositions and methods for silencing carbonic anhydrase 2 expression

Publications (2)

Publication Number Publication Date
JP2024522106A JP2024522106A (ja) 2024-06-11
JP2024522106A5 true JP2024522106A5 (https=) 2025-06-04

Family

ID=84230316

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023573112A Pending JP2024522106A (ja) 2021-05-27 2022-05-27 炭酸脱水酵素2発現をサイレンシングするための組成物および方法

Country Status (10)

Country Link
US (2) US20240254493A1 (https=)
EP (1) EP4347836A4 (https=)
JP (1) JP2024522106A (https=)
KR (1) KR20240014109A (https=)
AU (1) AU2022280088A1 (https=)
BR (1) BR112023024269A2 (https=)
CA (1) CA3220604A1 (https=)
IL (1) IL308574A (https=)
MX (1) MX2023014008A (https=)
WO (1) WO2022251629A2 (https=)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003295600A1 (en) * 2002-11-14 2004-06-15 Dharmacon, Inc. Functional and hyperfunctional sirna
HUE033977T2 (en) * 2004-08-23 2018-02-28 Sylentis Sau Treatment of eye disorders with siRNAs characterized by increased intraocular pressure
TW200639252A (en) * 2005-02-01 2006-11-16 Alcon Inc RNAi-mediated inhibition of ocular hypertension targets
RU2487716C2 (ru) * 2007-10-03 2013-07-20 Кварк Фармасьютикалс, Инк. Новые структуры малых интерферирующих рнк (sirna)
ES2351005B1 (es) * 2009-07-10 2011-11-18 Consejo Superior De Investigaciones Científicas (Csic) Uso de anhidrasa carbónica ii para la elaboración de un medicamento.
WO2017019660A1 (en) * 2015-07-27 2017-02-02 Alnylam Pharmaceuticals, Inc. Xanthine dehydrogenase (xdh) irna compositions and methods of use thereof
MX2020011570A (es) * 2018-05-07 2020-11-24 Alnylam Pharmaceuticals Inc Administracion extrahepatica.
WO2022026531A1 (en) * 2020-07-29 2022-02-03 Alnylam Pharmaceuticals, Inc. Atxn2 irna compositions and methods of use thereof for treating or preventing atxn2-associated neurodegenerative diseases

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