JP2024520307A - 複数のタスキニモド粒子およびその使用 - Google Patents

複数のタスキニモド粒子およびその使用 Download PDF

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Publication number
JP2024520307A
JP2024520307A JP2023570225A JP2023570225A JP2024520307A JP 2024520307 A JP2024520307 A JP 2024520307A JP 2023570225 A JP2023570225 A JP 2023570225A JP 2023570225 A JP2023570225 A JP 2023570225A JP 2024520307 A JP2024520307 A JP 2024520307A
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JP
Japan
Prior art keywords
cancer
particles
tasquinimod
dosage unit
range
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023570225A
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English (en)
Japanese (ja)
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JP2024520307A5 (https=
Inventor
ウェンマン,ハンス
Original Assignee
アクティブ バイオテック エイビー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by アクティブ バイオテック エイビー filed Critical アクティブ バイオテック エイビー
Publication of JP2024520307A publication Critical patent/JP2024520307A/ja
Publication of JP2024520307A5 publication Critical patent/JP2024520307A5/ja
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Powder Metallurgy (AREA)
JP2023570225A 2021-05-25 2022-05-23 複数のタスキニモド粒子およびその使用 Pending JP2024520307A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21175623 2021-05-25
EP21175623.4 2021-05-25
PCT/EP2022/063887 WO2022248401A1 (en) 2021-05-25 2022-05-23 A plurality of tasquinimod particles and use thereof

Publications (2)

Publication Number Publication Date
JP2024520307A true JP2024520307A (ja) 2024-05-24
JP2024520307A5 JP2024520307A5 (https=) 2025-05-21

Family

ID=76098832

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023570225A Pending JP2024520307A (ja) 2021-05-25 2022-05-23 複数のタスキニモド粒子およびその使用

Country Status (14)

Country Link
US (2) US12485095B2 (https=)
EP (1) EP4346773B1 (https=)
JP (1) JP2024520307A (https=)
KR (1) KR20240012436A (https=)
CN (1) CN117295492A (https=)
AU (1) AU2022281056A1 (https=)
BR (1) BR112023023715A2 (https=)
CA (1) CA3218977A1 (https=)
ES (1) ES3048983T3 (https=)
IL (1) IL308542A (https=)
MX (1) MX2023013301A (https=)
PL (1) PL4346773T3 (https=)
WO (1) WO2022248401A1 (https=)
ZA (1) ZA202311594B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025228998A1 (en) * 2024-04-30 2025-11-06 Institut National de la Santé et de la Recherche Médicale Use of hdac4 inhibitors for the treatment of melanoma

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801474D0 (sv) 1998-04-27 1998-04-27 Active Biotech Ab Quinoline Derivatives
SE9802549D0 (sv) 1998-07-15 1998-07-15 Active Biotech Ab Quinoline derivatives
SE0002320D0 (sv) 1999-10-25 2000-06-21 Active Biotech Ab Malignant tumors
SE0201778D0 (sv) 2002-06-12 2002-06-12 Active Biotech Ab Process for the manufacture of quinoline derivatives
SG186430A1 (en) 2010-07-09 2013-01-30 Active Biotech Ab Method for manufacturing of quinoline-3-carboxamides
EP2537517A1 (en) 2011-06-22 2012-12-26 Active Biotech AB Deuterium-enriched 4-hydroxy-5-methoxy-n,1-dimethyl-2-oxo-n-[(4-trifluoro-methyl)phenyl]-1,2-dihydroquinoline-3-carboxamide
US10213422B2 (en) 2014-04-14 2019-02-26 Yale University Compositions and methods of inhibiting histone deacetylases
JP6647287B2 (ja) 2014-09-23 2020-02-14 アクティブ バイオテック エイビー 多発性骨髄腫の治療に使用するためのキノリンカルボキサミド
MX379401B (es) 2014-11-19 2025-03-11 Active Biotech Ab Carboxamidas de quinolina para usarse en el tratamiento de leucemia.
EP3067062A1 (en) 2015-03-13 2016-09-14 Ipsen Pharma S.A.S. Combination of tasquinimod or a pharmaceutically acceptable salt thereof and a pd1 and/or pdl1 inhibitor, for use as a medicament
WO2018105943A1 (ko) 2016-12-07 2018-06-14 순천향대학교 산학협력단 폐섬유증 또는 천식의 치료 또는 완화용 약학 조성물
BR112023000892A2 (pt) 2020-07-23 2023-02-07 Univ Erasmus Med Ct Rotterdam Inibidor de uma proteína s100 para uso na prevenção ou tratamento de uma neoplasia mieloproliferativa, agente e método para identificar um indivíduo que sofre de uma neoplasia mieloproliferativa, e, métodos para identificar um indivíduo em risco de desenvolver mielofibrose e que se beneficie de um tratamento com um inibidor
ES3057099T3 (en) 2021-01-18 2026-02-26 Active Biotech Ab Tasquinimod or a pharmaceutically acceptable salt thereof for use in the treatment of myelodysplastic syndrome

Also Published As

Publication number Publication date
ZA202311594B (en) 2025-04-30
AU2022281056A1 (en) 2023-11-30
IL308542A (en) 2024-01-01
BR112023023715A2 (pt) 2024-02-20
EP4346773C0 (en) 2025-07-02
US20240285532A1 (en) 2024-08-29
CA3218977A1 (en) 2022-12-01
EP4346773B1 (en) 2025-07-02
EP4346773A1 (en) 2024-04-10
CN117295492A (zh) 2023-12-26
WO2022248401A1 (en) 2022-12-01
ES3048983T3 (en) 2025-12-12
US12485095B2 (en) 2025-12-02
KR20240012436A (ko) 2024-01-29
US20260076908A1 (en) 2026-03-19
PL4346773T3 (pl) 2025-11-03
MX2023013301A (es) 2023-12-04

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