JP2024519536A5 - - Google Patents
Info
- Publication number
- JP2024519536A5 JP2024519536A5 JP2023572137A JP2023572137A JP2024519536A5 JP 2024519536 A5 JP2024519536 A5 JP 2024519536A5 JP 2023572137 A JP2023572137 A JP 2023572137A JP 2023572137 A JP2023572137 A JP 2023572137A JP 2024519536 A5 JP2024519536 A5 JP 2024519536A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- group
- ligase
- pxr
- linker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR2105217 | 2021-05-19 | ||
| FR2105217A FR3122989B1 (fr) | 2021-05-19 | 2021-05-19 | Nouveaux composes bifonctionnels de type protac ciblant pxr, leur procede de preparation et leur utilisation en therapeutique |
| PCT/EP2022/063422 WO2022243365A1 (fr) | 2021-05-19 | 2022-05-18 | Composés bifonctionnels de type protac ciblant pxr, leur procédé de préparation et leur utilisation en thérapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024519536A JP2024519536A (ja) | 2024-05-15 |
| JP2024519536A5 true JP2024519536A5 (https=) | 2025-06-02 |
Family
ID=76284058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023572137A Pending JP2024519536A (ja) | 2021-05-19 | 2022-05-18 | Ｐｘｒを標的とする二官能性ｐｒｏｔａｃ型化合物、同化合物を調製するための方法、及びその治療的使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240252658A1 (https=) |
| EP (1) | EP4340887A1 (https=) |
| JP (1) | JP2024519536A (https=) |
| CN (1) | CN117295523A (https=) |
| CA (1) | CA3218875A1 (https=) |
| FR (1) | FR3122989B1 (https=) |
| WO (1) | WO2022243365A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118344284A (zh) * | 2024-03-06 | 2024-07-16 | 杭州医学院 | 一种具有苯甲酰胺结构的化合物及其制备方法和应用 |
| CN121735909A (zh) * | 2024-09-27 | 2026-03-27 | 上海交通大学医学院附属瑞金医院 | 多价分子胶类化合物及其制备和应用 |
| US20260092058A1 (en) | 2024-09-30 | 2026-04-02 | St. Jude Children's Research Hospital, Inc. | Small Molecule Degraders and Fluorescent Probes of PXR |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017223415A1 (en) * | 2016-06-23 | 2017-12-28 | Dana-Farber Cancer Institute, Inc. | Degradation of tripartite motif-containing protein 24 (trim24) by conjugation of trim24 inhibitors with e3 ligase ligand and methods of use |
-
2021
- 2021-05-19 FR FR2105217A patent/FR3122989B1/fr active Active
-
2022
- 2022-05-18 JP JP2023572137A patent/JP2024519536A/ja active Pending
- 2022-05-18 US US18/562,251 patent/US20240252658A1/en active Pending
- 2022-05-18 EP EP22733859.7A patent/EP4340887A1/fr active Pending
- 2022-05-18 WO PCT/EP2022/063422 patent/WO2022243365A1/fr not_active Ceased
- 2022-05-18 CN CN202280035417.4A patent/CN117295523A/zh active Pending
- 2022-05-18 CA CA3218875A patent/CA3218875A1/fr active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024519536A5 (https=) | ||
| JP5503872B2 (ja) | 核酸系代謝拮抗剤の高分子誘導体 | |
| ES2426599T3 (es) | Formulación oral anticáncer | |
| AU656689B2 (en) | Multi-site metal chelating agents | |
| JP5548365B2 (ja) | 核酸系代謝拮抗剤の高分子誘導体 | |
| CA3035697A1 (en) | Biaryl compounds useful as immunomodulators | |
| US12606525B2 (en) | Dimethyltryptamine analogues as nitric oxide delivery drugs | |
| JP2010532380A5 (https=) | ||
| JP2007501862A5 (https=) | ||
| RU2007105350A (ru) | 3-(гетероарилокси)-2-алкил-1-азабициклоалкильные производные, как лиганды альфа-7-nachr (никотиновых ацетилхолиновых рецепторов), предназначенные для лечения заболеваний центральной нервной системы | |
| CA2653941A1 (en) | Substituted amino purine derivatives and uses thereof | |
| JP2020520926A5 (https=) | ||
| JP2020508985A5 (https=) | ||
| ES2785409T3 (es) | Formas sólidas de un compuesto antiviral | |
| US20230302144A1 (en) | Porphyrin Compounds and Compositions Useful for Treating Cancer | |
| JP2007505044A5 (https=) | ||
| JP2024501537A5 (https=) | ||
| TW200922623A (en) | Polymeric drug delivery systems containing an aromatic allylic acid | |
| JP2023505509A (ja) | ポリエチレングリコール複合薬、ならびにその調製方法およびその使用 | |
| HU215129B (hu) | Daganatellenes hatású, trinukleáris kationos platinakomplexek, eljárás előállításukra és ilyen vegyületeket tartalmazó gyógyászati készítmények | |
| JPH0725678B2 (ja) | がん治療用白金挿入組成物 | |
| JP2005501121A5 (https=) | ||
| HUE029466T2 (en) | Multifunctional nitroxide derivatives and their use | |
| EP1140200B1 (en) | Anthraquinone anticancer drugs | |
| CN121620519A (zh) | 新型GalNAc的靶向递送片段及其制备和应用 |