JP2024519140A5 - - Google Patents

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Publication number
JP2024519140A5
JP2024519140A5 JP2023572596A JP2023572596A JP2024519140A5 JP 2024519140 A5 JP2024519140 A5 JP 2024519140A5 JP 2023572596 A JP2023572596 A JP 2023572596A JP 2023572596 A JP2023572596 A JP 2023572596A JP 2024519140 A5 JP2024519140 A5 JP 2024519140A5
Authority
JP
Japan
Application number
JP2023572596A
Other languages
Japanese (ja)
Other versions
JP2024519140A (ja
JPWO2022246576A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2022/050864 external-priority patent/WO2022246576A1/en
Publication of JP2024519140A publication Critical patent/JP2024519140A/ja
Publication of JP2024519140A5 publication Critical patent/JP2024519140A5/ja
Publication of JPWO2022246576A5 publication Critical patent/JPWO2022246576A5/ja
Pending legal-status Critical Current

Links

JP2023572596A 2021-05-27 2022-05-27 カンプトテシン類似体、複合体及び使用の方法 Pending JP2024519140A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163194138P 2021-05-27 2021-05-27
US63/194,138 2021-05-27
US202163203667P 2021-07-27 2021-07-27
US63/203,667 2021-07-27
US202163290587P 2021-12-16 2021-12-16
US63/290,587 2021-12-16
PCT/CA2022/050864 WO2022246576A1 (en) 2021-05-27 2022-05-27 Camptothecin analogues, conjugates and methods of use

Publications (3)

Publication Number Publication Date
JP2024519140A JP2024519140A (ja) 2024-05-08
JP2024519140A5 true JP2024519140A5 (https=) 2025-08-01
JPWO2022246576A5 JPWO2022246576A5 (https=) 2025-08-01

Family

ID=84229147

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023572596A Pending JP2024519140A (ja) 2021-05-27 2022-05-27 カンプトテシン類似体、複合体及び使用の方法

Country Status (10)

Country Link
US (1) US20240269309A1 (https=)
EP (1) EP4347601A4 (https=)
JP (1) JP2024519140A (https=)
KR (1) KR20240031235A (https=)
AU (1) AU2022282813A1 (https=)
BR (1) BR112023024433A2 (https=)
CA (1) CA3177067A1 (https=)
IL (1) IL308734A (https=)
MX (1) MX2023013738A (https=)
WO (1) WO2022246576A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022238571A1 (en) 2021-03-18 2023-09-14 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds
CA3228345A1 (en) * 2021-08-19 2023-02-23 Zhen Li Camptothecin derivative, and pharmaceutical composition and use thereof
CN118414339A (zh) * 2021-12-16 2024-07-30 迈威(上海)生物科技股份有限公司 一种喜树碱类化合物及其偶联物
IL315508A (en) * 2022-03-17 2024-11-01 Seagen Inc Camptothecin conjugates
IL315393A (en) * 2022-03-25 2024-11-01 Zymeworks Bc Inc Antibody preparations for drugs targeting alpha acid receptor and methods of use
EP4524140A1 (en) * 2022-05-13 2025-03-19 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Camptothecin compound, preparation method therefor and use thereof
CN116675727A (zh) * 2022-12-28 2023-09-01 广州医科大学 一种以不保护氨基酸为氨组分合成酰胺和/或多肽的方法
CN117281809A (zh) * 2023-03-09 2023-12-26 兰州大学 喜树碱类衍生物在制备治疗膀胱癌药物中的应用
EP4720075A1 (en) * 2023-05-26 2026-04-08 NJ Bio, Inc. Topoisomerase inhibitors, methods of making, and methods of use thereof
WO2024255740A1 (zh) * 2023-06-13 2024-12-19 成都倍特药业股份有限公司 用于治疗或预防癌症的喜树碱衍生物及其抗体药物偶联物
WO2025078841A2 (en) 2023-10-11 2025-04-17 Antikor Biopharma Limited Antibodies, conjugates, and uses thereof
WO2025080693A1 (en) * 2023-10-11 2025-04-17 Minerva Biotechnologies Corporation Anti-muc1* antibody drug complexes and uses thereof
TW202530268A (zh) * 2023-10-19 2025-08-01 加拿大商酵活英屬哥倫比亞有限公司 抗napi2b抗體-藥物結合物及使用方法
WO2025235686A1 (en) * 2024-05-07 2025-11-13 Aarvik Therapeutics, Inc. Fluorocamptothecin compounds, conjugates, and methods thereof
KR20250170534A (ko) * 2024-05-28 2025-12-05 한미약품 주식회사 항종양 활성을 지니는 신규한 설파마이드 캄토테신 유도체

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136978A (en) * 1993-06-30 2000-10-24 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
GB9402934D0 (en) * 1994-02-16 1994-04-06 Erba Carlo Spa Camptothecin derivatives and process for their preparation
JP2002255821A (ja) * 2001-03-06 2002-09-11 Yakult Honsha Co Ltd 抗癌剤耐性癌に対する治療剤
AU2018237683A1 (en) * 2017-03-24 2019-10-31 Seagen Inc. Process for the preparation of glucuronide drug-linkers and intermediates thereof
JP7561141B2 (ja) * 2019-04-26 2024-10-03 イミュノジェン・インコーポレーテッド カンプトテシン誘導体
CN110128501A (zh) * 2019-05-21 2019-08-16 北京海美源医药科技有限公司 一种靶向fap酶的喜树碱类化合物及其制备方法和应用
IL299001A (en) * 2020-06-19 2023-02-01 Hangzhou Dac Biotech Co Ltd Pairings of a cell-binding molecule with camptocin analogs
MX2023008895A (es) * 2021-02-09 2023-08-09 Medilink Therapeutics Suzhou Co Ltd Conjugado de sustancia bioactiva, metodo de preparacion y uso del mismo.
MX2023010819A (es) * 2021-03-18 2023-09-28 Seagen Inc Liberacion selectiva de farmacos a partir de conjugados internalizados de compuestos biologicamente activos.
CN117980327A (zh) * 2021-11-03 2024-05-03 杭州多禧生物科技有限公司 抗体的特异性偶联

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