JP2024515062A - 重水素化ｄｈｏｄｈ阻害剤 - Google Patents

重水素化ｄｈｏｄｈ阻害剤 Download PDF

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JP2024515062A
JP2024515062A JP2023561906A JP2023561906A JP2024515062A JP 2024515062 A JP2024515062 A JP 2024515062A JP 2023561906 A JP2023561906 A JP 2023561906A JP 2023561906 A JP2023561906 A JP 2023561906A JP 2024515062 A JP2024515062 A JP 2024515062A
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alkylene
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deuterium
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JPWO2022214691A5 (https=
JP2024515062A5 (https=
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ゲーゲ クリスティアン
コールホフ ヘラ
ミューラー アンドレアス
ビット ダニエル
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イミュニック アクチェンゲゼルシャフト
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    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
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    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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TW202506107A (zh) 2023-06-28 2025-02-16 德商埃慕尼克股份公司 雜芳族dhodh抑制劑
WO2025215126A1 (en) 2024-04-12 2025-10-16 Immunic Ag Synthesis of vidofludimus and its calcium salt
WO2026074007A1 (en) 2024-10-02 2026-04-09 Immunic Ag Nurr1 agonists with replacement of the carboxylic acid or carboxamide moiety for use in the treatment of neurodegenerative diseases

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