JP2024509920A5 - - Google Patents

Info

Publication number
JP2024509920A5
JP2024509920A5 JP2023555245A JP2023555245A JP2024509920A5 JP 2024509920 A5 JP2024509920 A5 JP 2024509920A5 JP 2023555245 A JP2023555245 A JP 2023555245A JP 2023555245 A JP2023555245 A JP 2023555245A JP 2024509920 A5 JP2024509920 A5 JP 2024509920A5
Authority
JP
Japan
Prior art keywords
egfr
cancer
formulation according
seq
bispecific anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023555245A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024509920A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/052009 external-priority patent/WO2022189942A1/en
Publication of JP2024509920A publication Critical patent/JP2024509920A/ja
Publication of JP2024509920A5 publication Critical patent/JP2024509920A5/ja
Pending legal-status Critical Current

Links

JP2023555245A 2021-03-09 2022-03-07 Egfr活性化変異を欠くがんの治療 Pending JP2024509920A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163158552P 2021-03-09 2021-03-09
US63/158,552 2021-03-09
PCT/IB2022/052009 WO2022189942A1 (en) 2021-03-09 2022-03-07 Treatment of cancers lacking egfr-activating mutations

Publications (2)

Publication Number Publication Date
JP2024509920A JP2024509920A (ja) 2024-03-05
JP2024509920A5 true JP2024509920A5 (enExample) 2025-03-13

Family

ID=80738936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023555245A Pending JP2024509920A (ja) 2021-03-09 2022-03-07 Egfr活性化変異を欠くがんの治療

Country Status (13)

Country Link
US (1) US20220298248A1 (enExample)
EP (1) EP4304644A1 (enExample)
JP (1) JP2024509920A (enExample)
KR (1) KR20230156094A (enExample)
CN (1) CN116997358A (enExample)
AU (1) AU2022233518A1 (enExample)
BR (1) BR112023018278A2 (enExample)
CA (1) CA3212669A1 (enExample)
CL (2) CL2023002663A1 (enExample)
IL (1) IL305700A (enExample)
JO (1) JOP20230211A1 (enExample)
MX (1) MX2023010633A (enExample)
WO (1) WO2022189942A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116194141A (zh) 2020-08-25 2023-05-30 詹森生物科技公司 具有egfr突变的非小细胞肺癌的治疗

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0281604B1 (en) 1986-09-02 1993-03-31 Enzon Labs Inc. Single polypeptide chain binding molecules
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ES2156149T3 (es) 1992-12-04 2001-06-16 Medical Res Council Proteinas de union multivalente y multiespecificas, su fabricacion y su uso.
AUPO591797A0 (en) 1997-03-27 1997-04-24 Commonwealth Scientific And Industrial Research Organisation High avidity polyvalent and polyspecific reagents
EP3042964A1 (en) 2004-06-04 2016-07-13 Genentech, Inc. Egfr mutations
WO2006028936A2 (en) 2004-09-02 2006-03-16 Genentech, Inc. Heteromultimeric molecules
AU2006232287B2 (en) 2005-03-31 2011-10-06 Chugai Seiyaku Kabushiki Kaisha Methods for producing polypeptides by regulating polypeptide association
DE102005028778A1 (de) 2005-06-22 2006-12-28 SUNJÜT Deutschland GmbH Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
PT1999154E (pt) 2006-03-24 2013-01-24 Merck Patent Gmbh Domínios proteicos heterodiméricos modificados
JP2009541275A (ja) 2006-06-22 2009-11-26 ノボ・ノルデイスク・エー/エス 二重特異性抗体の生産
KR20100058509A (ko) 2007-07-31 2010-06-03 메디뮨 엘엘씨 다중특이적 에피토프 결합 단백질 및 이의 용도
US9266967B2 (en) 2007-12-21 2016-02-23 Hoffmann-La Roche, Inc. Bivalent, bispecific antibodies
US8227577B2 (en) 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
US20090162359A1 (en) 2007-12-21 2009-06-25 Christian Klein Bivalent, bispecific antibodies
US8242247B2 (en) 2007-12-21 2012-08-14 Hoffmann-La Roche Inc. Bivalent, bispecific antibodies
WO2010129304A2 (en) 2009-04-27 2010-11-11 Oncomed Pharmaceuticals, Inc. Method for making heteromultimeric molecules
HRP20241208T1 (hr) 2010-04-20 2024-11-22 Genmab A/S Heterodimerni proteini koji sadrže fc fragment protutijela i postupci za njihovu proizvodnju
ES2758994T3 (es) 2010-11-05 2020-05-07 Zymeworks Inc Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc
BR112014010580B1 (pt) 2011-11-04 2021-01-12 Zymeworks, Inc. constructo de fc heteromultimérico isolado, composição, uso de um constructo de fc heteromultimérico isolado, composição de ácido nucléico e método para expressar o constructo de fc heteromultimérico isolado
MX361088B (es) * 2012-11-21 2018-11-26 Janssen Biotech Inc Anticuerpos del receptor del factor de crecimiento epidérmico aislado/del receptor del factor de crecimiento de hepatocitos (egfr/c-met) biespecíficos.
JP6520705B2 (ja) * 2013-03-19 2019-05-29 凸版印刷株式会社 Egfr阻害剤感受性予測方法
KR102771603B1 (ko) 2016-11-17 2025-02-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 Egfr 또는 her2 엑손 20 돌연변이를 갖는 암 세포에 대한 항종양 활성을 갖는 화합물
BR112021016149A2 (pt) * 2019-02-26 2021-10-13 Janssen Biotech, Inc. Terapias de combinação e estratificação de pacientes com anticorpos biespecíficos anti-egfr/c-met

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