JP2024509269A5 - - Google Patents

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Publication number
JP2024509269A5
JP2024509269A5 JP2023555290A JP2023555290A JP2024509269A5 JP 2024509269 A5 JP2024509269 A5 JP 2024509269A5 JP 2023555290 A JP2023555290 A JP 2023555290A JP 2023555290 A JP2023555290 A JP 2023555290A JP 2024509269 A5 JP2024509269 A5 JP 2024509269A5
Authority
JP
Japan
Prior art keywords
mutation
pharmaceutical composition
nras
composition according
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023555290A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024509269A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/019273 external-priority patent/WO2022192202A1/en
Publication of JP2024509269A publication Critical patent/JP2024509269A/ja
Publication of JP2024509269A5 publication Critical patent/JP2024509269A5/ja
Pending legal-status Critical Current

Links

JP2023555290A 2021-03-09 2022-03-08 脳がんの治療における使用のためのベルバラフェニブ Pending JP2024509269A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163158798P 2021-03-09 2021-03-09
US63/158,798 2021-03-09
PCT/US2022/019273 WO2022192202A1 (en) 2021-03-09 2022-03-08 Belvarafenib for use in treatment of brain cancers

Publications (2)

Publication Number Publication Date
JP2024509269A JP2024509269A (ja) 2024-02-29
JP2024509269A5 true JP2024509269A5 (https=) 2025-03-17

Family

ID=80952247

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023555290A Pending JP2024509269A (ja) 2021-03-09 2022-03-08 脳がんの治療における使用のためのベルバラフェニブ

Country Status (7)

Country Link
US (1) US20240173329A1 (https=)
EP (1) EP4304592A1 (https=)
JP (1) JP2024509269A (https=)
KR (1) KR20230156731A (https=)
CN (1) CN117940130A (https=)
TW (1) TW202300151A (https=)
WO (1) WO2022192202A1 (https=)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1934174T1 (sl) 2005-10-07 2011-08-31 Exelixis Inc Inhibitorji MEK in postopki za njihovo uporabo
CL2008001933A1 (es) * 2007-06-29 2009-09-25 Millennium Pharm Inc Compuestos derivados de pirimidina, inhibidores de la raf quinasa; compuestos intermediarios; procedimiento de preparacion; composicion farmaceutica; y su uso para tratar trastornos proliferativos, cardiacos, neurodegenerativos, inflamatorios, oseos, inmunologicos enfermedad viral, entre otros.
BR112014015720B1 (pt) 2011-12-30 2020-03-17 Hanmi Pharm. Co., Ltd. Derivados de tieno[3,2-d]pirimidina, composição farmacêutica e uso dos mesmos para a prevenção ou tratamento de uma doença causada por ativação anormal de uma proteína quinase
KR20190057421A (ko) 2012-08-17 2019-05-28 에프. 호프만-라 로슈 아게 코비메티닙 및 베무라피닙을 투여함을 포함하는 흑색종의 조합 치료법
KR102204520B1 (ko) 2012-10-12 2021-01-20 엑셀리시스, 인코포레이티드 암의 치료에 사용하기 위한 화합물의 신규 제조 방법
EP3624896A4 (en) * 2017-05-16 2021-03-31 Biomed Valley Discoveries, Inc. COMPOSITIONS AND METHODS OF TREATMENT OF CANCER WITH ATYPICAL BRAF MUTATIONS
IL274969B2 (en) * 2017-11-30 2026-03-01 Hanmi Pharmaceutical Co Ltd Salts of 4-amino-N-(1-((3-chloro-2-fluorophenyl)amino)-6-methylisoquinolin-5-yl)thieno[2,3-D]pyrimidine-7-carboxamide, and crystalline forms thereof
EP3560516A1 (en) * 2018-04-27 2019-10-30 Bergen Teknologioverforing AS Combination therapy including beta-sitosterol in combination with at least one of a braf inhibitor, a mek inhibitor or an erk inhibitor and methods and use thereof
TWI817018B (zh) * 2019-06-28 2023-10-01 美商艾瑞生藥股份有限公司 用於治療braf相關的疾病和失調症之化合物
CA3178927A1 (en) * 2020-05-26 2021-12-02 Hanmi Pharm. Co., Ltd. Belvarafenib for use in cancer treatment

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