JP2024508780A5 - - Google Patents

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Publication number
JP2024508780A5
JP2024508780A5 JP2023550150A JP2023550150A JP2024508780A5 JP 2024508780 A5 JP2024508780 A5 JP 2024508780A5 JP 2023550150 A JP2023550150 A JP 2023550150A JP 2023550150 A JP2023550150 A JP 2023550150A JP 2024508780 A5 JP2024508780 A5 JP 2024508780A5
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JP
Japan
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group
compound according
item
alkyl
nucleotides
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Pending
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JP2023550150A
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English (en)
Japanese (ja)
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JP2024508780A (ja
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Priority claimed from PCT/IB2022/000074 external-priority patent/WO2022175749A1/en
Publication of JP2024508780A publication Critical patent/JP2024508780A/ja
Publication of JP2024508780A5 publication Critical patent/JP2024508780A5/ja
Pending legal-status Critical Current

Links

JP2023550150A 2021-02-18 2022-02-18 オリゴヌクレオチドおよび炭水化物をコンジュゲートするための組成物 Pending JP2024508780A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163151060P 2021-02-18 2021-02-18
US63/151,060 2021-02-18
PCT/IB2022/000074 WO2022175749A1 (en) 2021-02-18 2022-02-18 Compositions for conjugating oligonucleotides and carbohydrates

Publications (2)

Publication Number Publication Date
JP2024508780A JP2024508780A (ja) 2024-02-28
JP2024508780A5 true JP2024508780A5 (https=) 2025-02-26

Family

ID=81386899

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023550150A Pending JP2024508780A (ja) 2021-02-18 2022-02-18 オリゴヌクレオチドおよび炭水化物をコンジュゲートするための組成物

Country Status (5)

Country Link
US (1) US20250034561A1 (https=)
EP (1) EP4294449A1 (https=)
JP (1) JP2024508780A (https=)
CN (1) CN117222434A (https=)
WO (1) WO2022175749A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116444589B (zh) * 2023-06-15 2023-09-19 北京悦康科创医药科技股份有限公司 新型GalNAc化合物及其硫代寡核苷酸缀合物和偶联方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3889261A1 (en) 2007-08-27 2021-10-06 1Globe Health Institute LLC Compositions of asymmetric interfering rna and uses thereof
DK2992098T3 (da) * 2013-05-01 2019-06-17 Ionis Pharmaceuticals Inc Sammensætninger og fremgangsmåder til modulering af hbv- og ttr-ekspression
JOP20160211B1 (ar) * 2015-10-01 2021-08-17 Arrowhead Pharmaceuticals Inc تراكيب وأساليب لتثبيط تعبير جيني للـ lpa
WO2018185253A1 (en) * 2017-04-05 2018-10-11 Silence Therapeutics Gmbh Ligand modified double-stranded nucleic acids
WO2020123410A1 (en) * 2018-12-10 2020-06-18 Amgen Inc. CHEMICALLY-MODIFIED RNAi CONSTRUCTS AND USES THEREOF
CA3132170A1 (en) * 2019-04-18 2020-10-22 Michael BIERMER Combination therapy for treating hepatitis b virus infection
EP4126967A1 (en) * 2020-03-23 2023-02-08 Amgen Inc. Monoclonal antibodies to chemically-modified nucleic acids and uses thereof
AU2021373780A1 (en) * 2020-11-05 2023-06-08 Amgen Inc. METHODS FOR TREATING ATHEROSCLEROTIC CARDIOVASCULAR DISEASE WITH LPA-TARGETED RNAi CONSTRUCTS
WO2022152869A1 (en) * 2021-01-15 2022-07-21 Janssen Sciences Ireland Unlimited Company Use of oligonucleotides for individuals with hepatic impairment

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