JP2024508709A5 - - Google Patents

Info

Publication number
JP2024508709A5
JP2024508709A5 JP2023548578A JP2023548578A JP2024508709A5 JP 2024508709 A5 JP2024508709 A5 JP 2024508709A5 JP 2023548578 A JP2023548578 A JP 2023548578A JP 2023548578 A JP2023548578 A JP 2023548578A JP 2024508709 A5 JP2024508709 A5 JP 2024508709A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
antibody according
chain
variant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023548578A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024508709A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/016683 external-priority patent/WO2022178047A1/en
Publication of JP2024508709A publication Critical patent/JP2024508709A/ja
Publication of JP2024508709A5 publication Critical patent/JP2024508709A5/ja
Pending legal-status Critical Current

Links

JP2023548578A 2021-02-17 2022-02-17 抗cd123結合分子及びその使用法 Pending JP2024508709A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163150488P 2021-02-17 2021-02-17
US63/150,488 2021-02-17
US202163249455P 2021-09-28 2021-09-28
US63/249,455 2021-09-28
PCT/US2022/016683 WO2022178047A1 (en) 2021-02-17 2022-02-17 Anti-cd123 binding molecules and uses thereof

Publications (2)

Publication Number Publication Date
JP2024508709A JP2024508709A (ja) 2024-02-28
JP2024508709A5 true JP2024508709A5 (https=) 2025-02-21

Family

ID=82931699

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023548578A Pending JP2024508709A (ja) 2021-02-17 2022-02-17 抗cd123結合分子及びその使用法

Country Status (9)

Country Link
US (1) US20240076392A1 (https=)
EP (1) EP4294829A4 (https=)
JP (1) JP2024508709A (https=)
KR (1) KR20230146022A (https=)
AU (1) AU2022221633A1 (https=)
CA (1) CA3205834A1 (https=)
IL (1) IL304485A (https=)
MX (1) MX2023009615A (https=)
WO (1) WO2022178047A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3560954T3 (pl) 2014-04-03 2021-12-13 Igm Biosciences, Inc. Zmodyfikowany łańcuch J
IL308212A (en) 2015-01-20 2024-01-01 Igm Biosciences Inc Tumor necrosis factor-α receptor binding molecules and their uses
EP3355913B1 (en) 2015-09-30 2024-10-30 IGM Biosciences, Inc. Binding molecules with modified j-chain
EP3356401B1 (en) 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9573988B2 (en) * 2013-02-20 2017-02-21 Novartis Ag Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells
WO2014138306A1 (en) * 2013-03-05 2014-09-12 Baylor College Of Medicine Engager cells for immunotherapy
EP3957738A1 (en) * 2015-03-04 2022-02-23 IGM Biosciences, Inc. Cd20 binding molecules and uses thereof
TWI790206B (zh) * 2016-07-18 2023-01-21 法商賽諾菲公司 特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白
CN109952112B (zh) * 2016-09-21 2024-09-06 阿帕特夫研究和发展有限公司 Cd123结合蛋白和相关的组合物和方法
BR112019010061A2 (pt) * 2016-11-16 2019-08-13 Ablynx Nv polipeptídeos de recrutamento de células t capazes de se ligarem ao cd123 e tcr alfa/beta
MX2019011986A (es) * 2017-04-07 2019-11-07 Igm Biosciences Inc Regiones constantes de igm humana modificadas para la modulacion de la funcion efectora de la citolisis dependiente de complemento referencia cruzada a solicitudes relacionadas.
KR20200041834A (ko) * 2017-06-01 2020-04-22 젠코어 인코포레이티드 Cd123 및 cd3에 결합하는 이중특이성 항체
MX2020009069A (es) * 2018-03-01 2020-10-08 Igm Biosciences Inc Mutaciones de fc de igm y de la cadena j que afectan la semivida de igm en suero.
EP3853254A1 (en) * 2018-09-20 2021-07-28 Lentigen Technology, Inc. Compositions and methods for treating cancer with anti-cd123 immunotherapy
JP2022532868A (ja) * 2019-05-04 2022-07-20 インヒブルクス インコーポレイテッド Cd123結合性ポリペプチド及びその使用
KR20220045030A (ko) * 2019-08-17 2022-04-12 아이쥐엠 바이오사이언스 인코포레이티드 다량체성 이중특이적 항-cd123 결합 분자 및 이의 용도

Similar Documents

Publication Publication Date Title
JP2024508709A5 (https=)
JP7411316B2 (ja) 三重特異性結合タンパク質と使用方法
JP2020063262A5 (https=)
RU2558301C2 (ru) Полипептиды для связывания с "рецептором конечных продуктов гликирования", а также их композиции и способы, в которых они принимают участие
JP2021502810A5 (https=)
JP2019196365A5 (https=)
CN111423512B (zh) 阻断血管内皮细胞生长且活化t细胞的多靶向融合蛋白和包含其的药物组合物
JP2022545655A5 (https=)
CA2798390A1 (en) Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies
JP2020508068A5 (https=)
KR20200123782A (ko) 암치료를 위해 화학치료제와 병용된 다중결합 항-dr5 결합분자의 용도
JP2013527761A5 (https=)
JP6242484B2 (ja) 特定の改善されたヒト二重特異性EGFRvIII抗体結合分子
JP2018504092A5 (https=)
JP2007532139A5 (https=)
AR039067A1 (es) Anticuerpos para cd40
JP2020521478A5 (https=)
RU2013134983A (ru) Рекомбинантные антитела против фактора роста эндотелия сосудов (vegf), полученные посредством мутагенеза вариабельной области
JP2023544143A5 (https=)
JP2025128343A5 (https=)
JP2010500006A5 (https=)
KR20230141817A (ko) 이중특이 항체
JP2024507693A5 (https=)
JP2015520172A5 (https=)
JP2022523360A5 (https=)