JP2024507693A5 - - Google Patents

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Publication number
JP2024507693A5
JP2024507693A5 JP2023545974A JP2023545974A JP2024507693A5 JP 2024507693 A5 JP2024507693 A5 JP 2024507693A5 JP 2023545974 A JP2023545974 A JP 2023545974A JP 2023545974 A JP2023545974 A JP 2023545974A JP 2024507693 A5 JP2024507693 A5 JP 2024507693A5
Authority
JP
Japan
Prior art keywords
antigen
amino acid
terminus
bispecific antibody
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023545974A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024507693A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/074133 external-priority patent/WO2022166728A1/zh
Publication of JP2024507693A publication Critical patent/JP2024507693A/ja
Publication of JP2024507693A5 publication Critical patent/JP2024507693A5/ja
Pending legal-status Critical Current

Links

JP2023545974A 2021-02-07 2022-01-27 二重特異性抗体 Pending JP2024507693A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN202110178932 2021-02-07
CN202110178932.5 2021-02-07
CN202110937430.6 2021-08-16
CN202110937430 2021-08-16
PCT/CN2022/074133 WO2022166728A1 (zh) 2021-02-07 2022-01-27 双特异性抗体

Publications (2)

Publication Number Publication Date
JP2024507693A JP2024507693A (ja) 2024-02-21
JP2024507693A5 true JP2024507693A5 (https=) 2025-02-03

Family

ID=82740913

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023545974A Pending JP2024507693A (ja) 2021-02-07 2022-01-27 二重特異性抗体

Country Status (12)

Country Link
US (1) US20240092899A1 (https=)
EP (1) EP4303231A4 (https=)
JP (1) JP2024507693A (https=)
KR (1) KR20230141817A (https=)
CN (2) CN118063620A (https=)
AU (1) AU2022215712A1 (https=)
BR (1) BR112023015217A2 (https=)
CA (1) CA3210307A1 (https=)
IL (1) IL304800A (https=)
MX (1) MX2023008966A (https=)
TW (1) TW202233694A (https=)
WO (1) WO2022166728A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL319262A (en) * 2018-12-24 2025-04-01 Sanofi Sa Multispecific FAB pseudoproteins bind
JP2024534976A (ja) * 2021-09-08 2024-09-26 ジョイント・ストック・カンパニー “バイオキャド” Mhcタンパク質に基づくヘテロ二量体を含む二重特異性抗体
CN118076644A (zh) * 2021-09-30 2024-05-24 正大天晴药业集团股份有限公司 针对免疫检查点的双特异性抗体
CN120344558A (zh) * 2022-12-08 2025-07-18 上海星赛生物科技有限公司 双特异性/多特异性抗体及其用途
WO2025213057A1 (en) * 2024-04-04 2025-10-09 Fletcher Biosciences, Inc. Engineered major histocompatibility complex molecules and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE517914T1 (de) * 2004-03-08 2011-08-15 Zymogenetics Inc Dimere fusionsproteine und materialien und verfahren zu deren herstellung
WO2014096015A1 (en) * 2012-12-21 2014-06-26 F. Hoffmann-La Roche Ag Disulfide-linked multivalent mhc class i comprising multi-function proteins
KR102476226B1 (ko) 2014-08-05 2022-12-12 아폴로믹스 인코포레이티드 항-pd-l1 항체
CA3014466A1 (en) * 2016-03-03 2017-09-08 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
WO2018220216A1 (en) * 2017-06-01 2018-12-06 Universität Stuttgart Heterodimerizing ig domains
AU2018290272A1 (en) * 2017-06-21 2020-01-30 Gsbio, Llc Heterodimeric bispecific antibodies
CN109422811A (zh) 2017-08-29 2019-03-05 信达生物制药(苏州)有限公司 抗cd47抗体及其用途
AU2018334886B2 (en) * 2017-09-22 2025-06-26 WuXi Biologics Ireland Limited Novel bispecific polypeptide complexes
AU2018414456B2 (en) * 2018-03-22 2025-09-11 Universität Stuttgart Multivalent binding molecules
WO2019195535A1 (en) 2018-04-05 2019-10-10 Novartis Ag Trispecific binding molecules against cancers and uses thereof
CN112384243A (zh) * 2018-04-17 2021-02-19 英温拉公司 三价三特异性抗体构建体
JP2022536581A (ja) * 2019-06-19 2022-08-18 キュー バイオファーマ, インコーポレイテッド 多量体t細胞調節性ポリペプチド及びその使用方法

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