JP2022545655A5 - - Google Patents

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Publication number
JP2022545655A5
JP2022545655A5 JP2022510108A JP2022510108A JP2022545655A5 JP 2022545655 A5 JP2022545655 A5 JP 2022545655A5 JP 2022510108 A JP2022510108 A JP 2022510108A JP 2022510108 A JP2022510108 A JP 2022510108A JP 2022545655 A5 JP2022545655 A5 JP 2022545655A5
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JP
Japan
Prior art keywords
seq
sequence number
sequence
amino acid
binding molecule
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JP2022510108A
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English (en)
Japanese (ja)
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JP2022545655A (ja
JP7585305B2 (ja
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Priority claimed from PCT/US2020/046335 external-priority patent/WO2021034646A1/en
Publication of JP2022545655A publication Critical patent/JP2022545655A/ja
Publication of JP2022545655A5 publication Critical patent/JP2022545655A5/ja
Application granted granted Critical
Publication of JP7585305B2 publication Critical patent/JP7585305B2/ja
Active legal-status Critical Current
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JP2022510108A 2019-08-17 2020-08-14 多量体の二重特異性抗cd123結合分子及びその使用 Active JP7585305B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962888475P 2019-08-17 2019-08-17
US62/888,475 2019-08-17
US201962888702P 2019-08-19 2019-08-19
US62/888,702 2019-08-19
PCT/US2020/046335 WO2021034646A1 (en) 2019-08-17 2020-08-14 Multimeric bispecific anti-cd123 binding molecules and uses thereof

Publications (3)

Publication Number Publication Date
JP2022545655A JP2022545655A (ja) 2022-10-28
JP2022545655A5 true JP2022545655A5 (https=) 2023-06-16
JP7585305B2 JP7585305B2 (ja) 2024-11-18

Family

ID=74659605

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022510108A Active JP7585305B2 (ja) 2019-08-17 2020-08-14 多量体の二重特異性抗cd123結合分子及びその使用

Country Status (10)

Country Link
US (1) US20220289856A1 (https=)
EP (1) EP4013796A4 (https=)
JP (1) JP7585305B2 (https=)
KR (1) KR20220045030A (https=)
CN (1) CN114341179B (https=)
AU (1) AU2020334882A1 (https=)
CA (1) CA3147767A1 (https=)
IL (1) IL289964A (https=)
MX (1) MX2022002024A (https=)
WO (1) WO2021034646A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3560954T3 (pl) 2014-04-03 2021-12-13 Igm Biosciences, Inc. Zmodyfikowany łańcuch J
IL308212A (en) 2015-01-20 2024-01-01 Igm Biosciences Inc Tumor necrosis factor-α receptor binding molecules and their uses
WO2016154593A1 (en) 2015-03-25 2016-09-29 Igm Biosciences, Inc. Multi-valent hepatitis b virus antigen binding molecules and uses thereof
EP3355913B1 (en) 2015-09-30 2024-10-30 IGM Biosciences, Inc. Binding molecules with modified j-chain
EP3356401B1 (en) 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain
MX2021014973A (es) 2019-06-07 2022-04-18 Adimab Llc Anticuerpos anti-cd3 de alta afinidad y metodos para su generacion y uso.
US20240076392A1 (en) * 2021-02-17 2024-03-07 Igm Biosciences, Inc. Anti-cd123 binding molecules and uses thereof
WO2022212191A1 (en) * 2021-04-01 2022-10-06 Modernatx, Inc. Mucosal expression of antibody structures and isotypes by mrna
JP2024530465A (ja) * 2021-08-06 2024-08-21 ウニバズィテート バーゼル 細胞療法に使用するための識別可能な細胞表面タンパク質変異体
EP4377360A4 (en) * 2021-09-17 2025-10-15 Adimab Llc Anti-cd3 antibodies

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6045774A (en) * 1997-01-10 2000-04-04 Epicyte Pharmaceutical Inc. J chain polypeptide targeting molecule linked to an imaging agent
PT3444271T (pt) * 2013-08-08 2022-01-05 Inst Nat Sante Rech Med Modulocinas baseadas em il-15 e no domínio sushi de il-15ralfa
PL3560954T3 (pl) * 2014-04-03 2021-12-13 Igm Biosciences, Inc. Zmodyfikowany łańcuch J
US10259887B2 (en) * 2014-11-26 2019-04-16 Xencor, Inc. Heterodimeric antibodies that bind CD3 and tumor antigens
CN120988137A (zh) * 2015-01-23 2025-11-21 赛诺菲 抗cd3抗体、抗cd123抗体和与cd3和/或cd123特异性结合的双特异性抗体
EP3355913B1 (en) * 2015-09-30 2024-10-30 IGM Biosciences, Inc. Binding molecules with modified j-chain
EP3356401B1 (en) * 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain
WO2017210443A1 (en) * 2016-06-01 2017-12-07 Xencor, Inc. Bispecific antibodies that bind cd123 and cd3
MX2019011986A (es) * 2017-04-07 2019-11-07 Igm Biosciences Inc Regiones constantes de igm humana modificadas para la modulacion de la funcion efectora de la citolisis dependiente de complemento referencia cruzada a solicitudes relacionadas.
CN118894936A (zh) * 2017-05-08 2024-11-05 阿迪马布有限责任公司 抗cd3结合结构域和包含它们的抗体以及它们的产生及使用方法
CN108409840B (zh) * 2017-05-18 2020-06-23 重庆精准生物技术有限公司 抗cd123单链抗体及其组合的嵌合抗原受体和应用
MX2020009069A (es) * 2018-03-01 2020-10-08 Igm Biosciences Inc Mutaciones de fc de igm y de la cadena j que afectan la semivida de igm en suero.

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