JP2022549186A5 - - Google Patents

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Publication number
JP2022549186A5
JP2022549186A5 JP2022517731A JP2022517731A JP2022549186A5 JP 2022549186 A5 JP2022549186 A5 JP 2022549186A5 JP 2022517731 A JP2022517731 A JP 2022517731A JP 2022517731 A JP2022517731 A JP 2022517731A JP 2022549186 A5 JP2022549186 A5 JP 2022549186A5
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JP
Japan
Prior art keywords
seq
binding
amino acid
binding molecule
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022517731A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022549186A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/051513 external-priority patent/WO2021055765A2/en
Publication of JP2022549186A publication Critical patent/JP2022549186A/ja
Publication of JP2022549186A5 publication Critical patent/JP2022549186A5/ja
Pending legal-status Critical Current

Links

JP2022517731A 2019-09-19 2020-09-18 高い標的密度の細胞に対する選択性を向上させた多量体抗体 Pending JP2022549186A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962902915P 2019-09-19 2019-09-19
US62/902,915 2019-09-19
PCT/US2020/051513 WO2021055765A2 (en) 2019-09-19 2020-09-18 Multimeric antibodies with enhanced selectivity for cells with high target density

Publications (2)

Publication Number Publication Date
JP2022549186A JP2022549186A (ja) 2022-11-24
JP2022549186A5 true JP2022549186A5 (https=) 2023-08-28

Family

ID=74884716

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022517731A Pending JP2022549186A (ja) 2019-09-19 2020-09-18 高い標的密度の細胞に対する選択性を向上させた多量体抗体

Country Status (8)

Country Link
US (1) US20220372142A1 (https=)
EP (1) EP4031252A4 (https=)
JP (1) JP2022549186A (https=)
CN (1) CN114616031A (https=)
AU (1) AU2020351205A1 (https=)
CA (1) CA3151237A1 (https=)
IL (1) IL291340A (https=)
WO (1) WO2021055765A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3560954T3 (pl) 2014-04-03 2021-12-13 Igm Biosciences, Inc. Zmodyfikowany łańcuch J
IL308212A (en) 2015-01-20 2024-01-01 Igm Biosciences Inc Tumor necrosis factor-α receptor binding molecules and their uses
WO2016154593A1 (en) 2015-03-25 2016-09-29 Igm Biosciences, Inc. Multi-valent hepatitis b virus antigen binding molecules and uses thereof
EP3355913B1 (en) 2015-09-30 2024-10-30 IGM Biosciences, Inc. Binding molecules with modified j-chain
EP3356401B1 (en) 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
WO2022212191A1 (en) * 2021-04-01 2022-10-06 Modernatx, Inc. Mucosal expression of antibody structures and isotypes by mrna
WO2023083381A1 (zh) 2021-11-15 2023-05-19 成都百利多特生物药业有限责任公司 双特异性抗体-喜树碱类药物偶联物及其医药用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006047350A2 (en) * 2004-10-21 2006-05-04 Xencor, Inc. IgG IMMUNOGLOBULIN VARIANTS WITH OPTIMIZED EFFECTOR FUNCTION
PL3560954T3 (pl) * 2014-04-03 2021-12-13 Igm Biosciences, Inc. Zmodyfikowany łańcuch J
EP3957738A1 (en) * 2015-03-04 2022-02-23 IGM Biosciences, Inc. Cd20 binding molecules and uses thereof
EP3356401B1 (en) * 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain
CA3035427A1 (en) * 2016-09-01 2018-03-08 Umc Utrecht Holding B.V. Cd20 antibodies
MX2019011986A (es) * 2017-04-07 2019-11-07 Igm Biosciences Inc Regiones constantes de igm humana modificadas para la modulacion de la funcion efectora de la citolisis dependiente de complemento referencia cruzada a solicitudes relacionadas.
MX2020009069A (es) * 2018-03-01 2020-10-08 Igm Biosciences Inc Mutaciones de fc de igm y de la cadena j que afectan la semivida de igm en suero.

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