JP2024503723A5 - - Google Patents

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Publication number
JP2024503723A5
JP2024503723A5 JP2023543239A JP2023543239A JP2024503723A5 JP 2024503723 A5 JP2024503723 A5 JP 2024503723A5 JP 2023543239 A JP2023543239 A JP 2023543239A JP 2023543239 A JP2023543239 A JP 2023543239A JP 2024503723 A5 JP2024503723 A5 JP 2024503723A5
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JP
Japan
Prior art keywords
pharmaceutical composition
adenosine derivative
derivative according
composition according
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023543239A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024503723A (ja
JP7843289B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/013660 external-priority patent/WO2022159872A1/en
Publication of JP2024503723A publication Critical patent/JP2024503723A/ja
Publication of JP2024503723A5 publication Critical patent/JP2024503723A5/ja
Application granted granted Critical
Publication of JP7843289B2 publication Critical patent/JP7843289B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023543239A 2021-01-25 2022-01-25 アデノシン誘導体及びそれを含む医薬組成物 Active JP7843289B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163141450P 2021-01-25 2021-01-25
US63/141,450 2021-01-25
PCT/US2022/013660 WO2022159872A1 (en) 2021-01-25 2022-01-25 Adenosine derivative and pharmaceutical composition comprising the same

Publications (3)

Publication Number Publication Date
JP2024503723A JP2024503723A (ja) 2024-01-26
JP2024503723A5 true JP2024503723A5 (https=) 2025-01-15
JP7843289B2 JP7843289B2 (ja) 2026-04-09

Family

ID=82494279

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023543239A Active JP7843289B2 (ja) 2021-01-25 2022-01-25 アデノシン誘導体及びそれを含む医薬組成物

Country Status (12)

Country Link
US (2) US11793827B2 (https=)
EP (1) EP4281081A4 (https=)
JP (1) JP7843289B2 (https=)
KR (1) KR20230132476A (https=)
CN (1) CN116710465A (https=)
AU (1) AU2022210781A1 (https=)
CA (1) CA3202049A1 (https=)
IL (1) IL304366A (https=)
MX (1) MX2023008004A (https=)
TW (1) TW202245805A (https=)
WO (1) WO2022159872A1 (https=)
ZA (1) ZA202408803B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3146679A1 (en) 2019-07-27 2021-02-04 Brii Biosciences, Inc. Adenosine derivative and pharmaceutical composition comprising the same
EP4281081A4 (en) 2021-01-25 2025-05-14 Brii Biosciences, Inc. ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF
EP4281083A4 (en) 2021-01-25 2025-01-01 Brii Biosciences, Inc. COMBINATION THERAPY FOR HIV WITH ADENOSINE DERIVATIVE AND CAPSID INHIBITORS
CR20250310A (es) * 2023-01-30 2025-08-25 Merck Sharp & Dohme Llc Profármacos de inhibidores de la transcriptasa inversa de nucleósidos sustituidos en 4'

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3407191A (en) * 1966-08-29 1968-10-22 Lilly Co Eli Adamantoate esters of nucleosides
US5880154A (en) 1994-02-01 1999-03-09 The Board Of Regents Of The University Of Nebraska Polymeric adamantane analogues
JP2007504232A (ja) 2003-09-05 2007-03-01 アナディス ファーマシューティカルズ インク C型肝炎ウイルス感染治療用のtlr7リガンド及びそのプロドラッグの投与
CA2502109C (en) 2004-03-24 2010-02-23 Yamasa Corporation 4'-c-substituted-2-haloadenosine derivative
WO2007022073A2 (en) 2005-08-12 2007-02-22 Merck & Co., Inc. Novel 2'-c-methyl and 4'-c-methyl nucleoside derivatives
WO2008011406A2 (en) 2006-07-18 2008-01-24 Anadys Pharmaceuticals, Inc. Carbonate and carbamate prodrugs of thiazolo [4,5-d] pyrimidines
WO2011058582A1 (en) 2009-11-16 2011-05-19 Orchid Research Laboratories Ltd. Histone deacetylase inhibitors for the treatment of fungal infections
WO2015143712A1 (en) 2014-03-28 2015-10-01 Merck Sharp & Dohme Corp. 4'-substituted nucleoside reverse transcriptase inhibitors
US9951141B2 (en) 2014-06-02 2018-04-24 Regeneron Pharmaceuticals, Inc. Antibody-drug conjugates, their preparation and their therapeutic use
MX391226B (es) * 2015-09-23 2025-03-21 Merck Sharp & Dohme Llc Inhibidores de transcriptasa inversa de nucleosido 4'-substituido y preparaciones de los mismos.
US20180030080A1 (en) * 2016-07-28 2018-02-01 Alexandre Vasilievich Ivachtchenko Phosphoramidate nucleoside prodrug for treating viral diseases and cancer, processes for their preparation and their use
US10266558B2 (en) * 2016-10-07 2019-04-23 Alexandre Vasilievich Ivachtchenko Macroheterocyclic nucleoside derivatives and their analogues, production and use thereof
RU2659388C1 (ru) * 2017-02-28 2018-07-02 Васильевич Иващенко Александр Нуклеотиды, включающие N-[(S)-1-циклобутоксикарбонил]фосфорамидатный фрагмент, их аналоги и их применение
DK3590924T3 (da) 2017-02-28 2022-01-03 Kangpu Biopharmaceuticals Inc Hidtil ukendt isoindolinderivat og farmaceutisk sammensætning og anvendelse deraf
US20190185508A1 (en) * 2017-12-15 2019-06-20 Merck Sharp & Dohme Corp. Deuterated nucleoside reverse transcriptase inhibitors
EP3762396A1 (en) 2018-03-07 2021-01-13 GlaxoSmithKline Intellectual Property (No.2) Limited Compounds useful in hiv therapy
CN109053803A (zh) 2018-07-04 2018-12-21 米文君 一类新的化合物及其用途
AU2019317810A1 (en) * 2018-08-09 2021-02-25 Glaxosmithkline Intellectual Property (No.2) Limited Compounds useful in HIV therapy
JP2021536444A (ja) 2018-08-30 2021-12-27 グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー2)、リミテッドGlaxosmithkline Intellectual Property (No.2) Limited Hiv療法に有用な化合物
CN113811360A (zh) 2019-03-06 2021-12-17 葛兰素史密斯克莱知识产权(第2 号)有限公司 用于hiv治疗的化合物
CA3146679A1 (en) 2019-07-27 2021-02-04 Brii Biosciences, Inc. Adenosine derivative and pharmaceutical composition comprising the same
WO2021038509A1 (en) 2019-08-28 2021-03-04 Glaxosmithkline Intellectual Property (No.2) Limited 4'-ethynyl-2'-deoxyadenosine derivatives and their use in hiv therapy
KR20220066303A (ko) 2019-09-11 2022-05-24 더 스크립스 리서치 인스티튜트 항바이러스 전구약물 및 이의 약제학적 조성물
EP4281081A4 (en) 2021-01-25 2025-05-14 Brii Biosciences, Inc. ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF
EP4281083A4 (en) 2021-01-25 2025-01-01 Brii Biosciences, Inc. COMBINATION THERAPY FOR HIV WITH ADENOSINE DERIVATIVE AND CAPSID INHIBITORS

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