JP2024503021A5 - - Google Patents

Info

Publication number
JP2024503021A5
JP2024503021A5 JP2023541734A JP2023541734A JP2024503021A5 JP 2024503021 A5 JP2024503021 A5 JP 2024503021A5 JP 2023541734 A JP2023541734 A JP 2023541734A JP 2023541734 A JP2023541734 A JP 2023541734A JP 2024503021 A5 JP2024503021 A5 JP 2024503021A5
Authority
JP
Japan
Prior art keywords
pyrimidine
pyrrolo
pyrazole
combination pharmaceutical
trifluoromethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023541734A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024503021A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/011756 external-priority patent/WO2022150676A1/en
Publication of JP2024503021A publication Critical patent/JP2024503021A/ja
Publication of JP2024503021A5 publication Critical patent/JP2024503021A5/ja
Pending legal-status Critical Current

Links

JP2023541734A 2021-01-11 2022-01-10 Ｊａｋ経路阻害剤及びｒｏｃｋ阻害剤を含む併用療法 Pending JP2024503021A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163135969P 2021-01-11 2021-01-11
US63/135,969 2021-01-11
US202163253384P 2021-10-07 2021-10-07
US63/253,384 2021-10-07
PCT/US2022/011756 WO2022150676A1 (en) 2021-01-11 2022-01-10 Combination therapy comprising jak pathway inhibitor and rock inhibitor

Publications (2)

Publication Number Publication Date
JP2024503021A JP2024503021A (ja) 2024-01-24
JP2024503021A5 true JP2024503021A5 (https=) 2025-01-24

Family

ID=80119468

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023541734A Pending JP2024503021A (ja) 2021-01-11 2022-01-10 Ｊａｋ経路阻害剤及びｒｏｃｋ阻害剤を含む併用療法

Country Status (11)

Country Link
US (2) US11918581B2 (https=)
EP (1) EP4274578A1 (https=)
JP (1) JP2024503021A (https=)
KR (1) KR20230157307A (https=)
AU (1) AU2022206313A1 (https=)
CA (1) CA3207859A1 (https=)
CL (2) CL2023002004A1 (https=)
IL (1) IL304320A (https=)
MX (1) MX2023008141A (https=)
TW (1) TW202237083A (https=)
WO (1) WO2022150676A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11992490B2 (en) 2019-10-16 2024-05-28 Incyte Corporation Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP)
WO2024153147A1 (zh) * 2023-01-18 2024-07-25 北京普祺医药科技股份有限公司 一种氮杂环烷烃化合物、药物组合物及其用途

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* Cited by examiner, † Cited by third party
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KR20150036210A (ko) 2007-06-13 2015-04-07 인사이트 코포레이션 야누스 키나제 억제제（Ｒ）―３―（４―（７Ｈ―피롤로［２，３－ｄ］피리미딘―4―일）―1Ｈ―피라졸―1―일）―３―사이클로펜틸프로판니트릴의 염
EP3828172A1 (en) 2009-05-01 2021-06-02 Aerie Pharmaceuticals, Inc. Dual mechanism inhibitors for the treatment of disease
AR076794A1 (es) 2009-05-22 2011-07-06 Incyte Corp Derivados de n-(hetero)aril-pirrolidina de pirazol-4-il-pirrolo [2,3-d]pirimidinas y pirrol-3-il-pirrolo [2,3-d ]pirimidinas como inhibidores de la quinasa janus y composiciones farmaceuticas que los contienen
TW201113285A (en) 2009-09-01 2011-04-16 Incyte Corp Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
EP3354652B1 (en) 2010-03-10 2020-05-06 Incyte Holdings Corporation Piperidin-4-yl azetidine derivatives as jak1 inhibitors
US9034884B2 (en) 2010-11-19 2015-05-19 Incyte Corporation Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors
PE20140146A1 (es) 2010-11-19 2014-02-06 Incyte Corp Derivados de pirrolopiridina y pirrolopirimidina sustituidos con ciclobutilo como inhibidores de jak
CN103797010B (zh) 2011-06-20 2016-02-24 因塞特控股公司 作为jak抑制剂的氮杂环丁烷基苯基、吡啶基或吡嗪基甲酰胺衍生物
TW201313721A (zh) 2011-08-18 2013-04-01 Incyte Corp 作為ｊａｋ抑制劑之環己基氮雜環丁烷衍生物
UA111854C2 (uk) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн Способи і проміжні сполуки для отримання інгібіторів jak
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RS62867B1 (sr) 2013-03-06 2022-02-28 Incyte Holdings Corp Postupci i intermedijeri za dobijanje inhibitora jak
HUE033587T2 (hu) 2013-05-17 2017-12-28 Incyte Corp Bipirazol-származékok mint JAK inhibitorok
SMT202000315T1 (it) 2013-08-07 2020-07-08 Incyte Corp Forme di dosaggio a rilascio prolungato per un inibitore di jak1
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