JP2024099628A5 - - Google Patents
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- JP2024099628A5 JP2024099628A5 JP2024066182A JP2024066182A JP2024099628A5 JP 2024099628 A5 JP2024099628 A5 JP 2024099628A5 JP 2024066182 A JP2024066182 A JP 2024066182A JP 2024066182 A JP2024066182 A JP 2024066182A JP 2024099628 A5 JP2024099628 A5 JP 2024099628A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical formulation
- concentration
- mannitol
- excipient
- lyophilized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410002665.6A CN104758922A (zh) | 2014-01-03 | 2014-01-03 | 纽兰格林制剂的配方 |
| CN201410002665.6 | 2014-01-03 | ||
| JP2020082456A JP7100083B2 (ja) | 2014-01-03 | 2020-05-08 | ニューレグリン調合剤の処方 |
| JP2022105452A JP7479068B2 (ja) | 2014-01-03 | 2022-06-30 | ニューレグリン調合剤の処方 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022105452A Division JP7479068B2 (ja) | 2014-01-03 | 2022-06-30 | ニューレグリン調合剤の処方 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024099628A JP2024099628A (ja) | 2024-07-25 |
| JP2024099628A5 true JP2024099628A5 (enExample) | 2024-10-08 |
Family
ID=53493186
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016544419A Active JP6703483B2 (ja) | 2014-01-03 | 2014-12-17 | ニューレグリン調合剤の処方 |
| JP2020082456A Active JP7100083B2 (ja) | 2014-01-03 | 2020-05-08 | ニューレグリン調合剤の処方 |
| JP2022105452A Active JP7479068B2 (ja) | 2014-01-03 | 2022-06-30 | ニューレグリン調合剤の処方 |
| JP2024066182A Pending JP2024099628A (ja) | 2014-01-03 | 2024-04-16 | ニューレグリン調合剤の処方 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016544419A Active JP6703483B2 (ja) | 2014-01-03 | 2014-12-17 | ニューレグリン調合剤の処方 |
| JP2020082456A Active JP7100083B2 (ja) | 2014-01-03 | 2020-05-08 | ニューレグリン調合剤の処方 |
| JP2022105452A Active JP7479068B2 (ja) | 2014-01-03 | 2022-06-30 | ニューレグリン調合剤の処方 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US10702585B2 (enExample) |
| EP (2) | EP3090756B2 (enExample) |
| JP (4) | JP6703483B2 (enExample) |
| KR (3) | KR102522140B1 (enExample) |
| CN (4) | CN110946993A (enExample) |
| AU (1) | AU2014375637A1 (enExample) |
| BR (1) | BR112016015660A2 (enExample) |
| CA (1) | CA2935607A1 (enExample) |
| RU (1) | RU2738158C2 (enExample) |
| WO (1) | WO2015101182A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006332340B2 (en) | 2005-12-30 | 2013-09-26 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Extended release of neuregulin for improved cardiac function |
| JP6096262B2 (ja) | 2009-08-25 | 2017-03-15 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー． | ニューレグリンに基づく心不全の治療方法 |
| CN102139095A (zh) | 2010-01-29 | 2011-08-03 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏缺血再灌注损伤的方法和组合物 |
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun （Shanghai）Science & Technology Limited | Compositions and methods for treating heart failure |
| EP2858636B1 (en) | 2012-06-07 | 2018-09-05 | Childrens Hospital Los Angeles | Methods for treating neutropenia using retinoid agonists |
| CN109276705B (zh) | 2012-10-08 | 2023-10-20 | 上海泽生科技开发股份有限公司 | 治疗糖尿病患者心力衰竭的组份和方法 |
| EP3610905B1 (en) | 2013-05-22 | 2021-03-31 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Extended release of neuregulin for treating heart failure |
| CN110946993A (zh) | 2014-01-03 | 2020-04-03 | 上海泽生科技开发股份有限公司 | 纽兰格林制剂的配方 |
| CN105497876B (zh) | 2014-09-24 | 2021-01-15 | 上海泽生科技开发股份有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏室性心律失常的方法和组合物 |
| CN111407882A (zh) | 2014-10-17 | 2020-07-14 | 上海泽生科技开发股份有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
| EP3774859B1 (en) | 2018-04-11 | 2024-03-13 | Salubris Biotherapeutics, Inc. | Human neuregulin-1 (nrg-1) recombinant fusion protein compositions and methods of use thereof |
| AR121035A1 (es) | 2019-04-01 | 2022-04-13 | Lilly Co Eli | Compuestos de neuregulina-4 y métodos de uso |
| CA3157354A1 (en) * | 2019-09-16 | 2021-03-25 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Recombinant human neuregulin derivatives and use thereof |
| JP7425459B2 (ja) * | 2019-10-11 | 2024-01-31 | 株式会社シノテスト | 安定化されたｈｍｇｂ１含有溶液 |
| US20230034390A1 (en) * | 2019-12-16 | 2023-02-02 | Seagen Inc. | High performance liquid chromatography quantification of excipients |
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| WO1989001489A1 (en) | 1987-08-10 | 1989-02-23 | Commonwealth Scientific And Industrial Research Or | Control of angiogenesis and compositions and methods therefor |
| US7115554B1 (en) | 1993-05-06 | 2006-10-03 | Acorda Therapeutics, Inc. | Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III |
| US5716930A (en) | 1991-04-10 | 1998-02-10 | Ludwig Institute For Cancer Research | Glial growth factors |
| US5530109A (en) | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
| US5834229A (en) | 1991-05-24 | 1998-11-10 | Genentech, Inc. | Nucleic acids vectors and host cells encoding and expressing heregulin 2-α |
| US6750196B1 (en) | 1995-03-27 | 2004-06-15 | Acorda Therapeutics | Methods of treating disorders of the eye |
| US5912326A (en) | 1995-09-08 | 1999-06-15 | President And Fellows Of Harvard College | Cerebellum-derived growth factors |
| CA2278151C (en) | 1997-02-10 | 2010-11-16 | Genentech, Inc. | Heregulin variants |
| WO1999018976A1 (en) | 1997-10-14 | 1999-04-22 | Cambridge Neuroscience, Inc. | Therapeutic methods comprising use of a neuregulin |
| US6054261A (en) | 1998-05-20 | 2000-04-25 | Q-Pharma, Inc. | Coenzyme Q10 compositions for organ protection during perfusion |
| AUPP785098A0 (en) | 1998-12-21 | 1999-01-21 | Victor Chang Cardiac Research Institute, The | Treatment of heart disease |
| US6635249B1 (en) | 1999-04-23 | 2003-10-21 | Cenes Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
| CN1138785C (zh) | 1999-06-04 | 2004-02-18 | 周明东 | 生长因子神经调节蛋白及其类似物的新应用 |
| AUPQ105799A0 (en) | 1999-06-18 | 1999-07-08 | Victor Chang Cardiac Research Institute, The | Cell growth inhibition |
| CA2400595A1 (en) | 2000-02-28 | 2001-09-07 | Decode Genetics Ehf | Human schizophrenia gene |
| MXPA02011656A (es) | 2000-05-23 | 2004-07-30 | Cenes Pharmaceuticals Inc | Moleculas de acido nucleico nrg-2, polipeptidos, y metodos de diagnostico y terapeuticos. |
| AU2001290864A1 (en) | 2000-09-12 | 2002-04-02 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Optimized cardiac contraction through differential phosphorylation of myosin |
| US6482624B2 (en) | 2000-11-14 | 2002-11-19 | Pe Corporation (Ny) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof |
| RU2180843C1 (ru) | 2001-02-19 | 2002-03-27 | Новокузнецкий государственный институт усовершенствования врачей | Способ профилактики повторного инфаркта миокарда |
| DE10124387A1 (de) * | 2001-05-18 | 2002-11-28 | Basf Ag | Hydrophob modifizierte Polyethylenimine und Polyvinylamine zur Antiknitterausrüstung von cellulosehaltigen Textilien |
| CN1498656A (zh) | 2002-11-08 | 2004-05-26 | 上海泽生科技开发有限公司 | 神经调节蛋白用于心肌梗死治疗的方法和组合物 |
| WO2003099320A1 (en) | 2002-05-24 | 2003-12-04 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
| WO2004050894A2 (en) | 2002-11-27 | 2004-06-17 | Artesian Therapeutics, Inc. | Heart failure gene determination and therapeutic screening |
| EP1631268A2 (en) | 2003-05-21 | 2006-03-08 | Board Of Regents The University Of Texas System | Inhibition of protein kinase c-mu (pkd) as a treatment for cardiac hypertrophy and heart failure |
| GB0413005D0 (en) | 2004-06-11 | 2004-07-14 | Coletica | Ligand |
| CA2583972A1 (en) | 2004-10-14 | 2006-10-19 | Adventures Plus Pty Ltd | A method for the treatment of gastrointestinal and other disorders with an admixture of vitamins and minerals |
| US20060160062A1 (en) | 2005-01-14 | 2006-07-20 | Young Lindon H | Perfusion and/or preservation solution for organs |
| WO2006081190A2 (en) * | 2005-01-25 | 2006-08-03 | Five Prime Therapeutics, Inc. | Compositions and methods for treating cardiac conditions |
| US20070141548A1 (en) | 2005-03-11 | 2007-06-21 | Jorg Kohl | Organ transplant solutions and method for transplanting organs |
| CN100361709C (zh) | 2005-08-30 | 2008-01-16 | 山东省生物药物研究院 | 一种对生命活性物质有保护作用的糖类组合 |
| CN1768859A (zh) | 2005-10-24 | 2006-05-10 | 天津大学 | 基于醛基的微粒表面多重生物功能因子组装方法 |
| US20070213264A1 (en) | 2005-12-02 | 2007-09-13 | Mingdong Zhou | Neuregulin variants and methods of screening and using thereof |
| CN101394861A (zh) * | 2005-12-30 | 2009-03-25 | 上海泽生科技开发有限公司 | 纽兰格林持续给药能改善心脏功能 |
| AU2006332340B2 (en) * | 2005-12-30 | 2013-09-26 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Extended release of neuregulin for improved cardiac function |
| ATE502998T1 (de) * | 2006-07-07 | 2011-04-15 | Procter & Gamble | Waschmittelzusammensetzungen |
| US9580515B2 (en) | 2006-08-21 | 2017-02-28 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Neukinase, a downstream protein of neuregulin |
| JP2010517023A (ja) | 2007-01-25 | 2010-05-20 | エフ．ホフマン−ラ ロシュ アーゲー | 心不全の評価におけるｉｇｆｂｐ−７の使用 |
| CN101310779A (zh) | 2007-05-25 | 2008-11-26 | 上海泽生科技开发有限公司 | 包含神经调节蛋白的装置及药物制剂 |
| CN101310766B (zh) | 2007-05-25 | 2014-04-16 | 上海泽生科技开发有限公司 | 神经调节蛋白的新用途 |
| US20090156488A1 (en) | 2007-09-12 | 2009-06-18 | Zensun (Shanghai) Science & Technology Limited | Use of neuregulin for organ preservation |
| US20110212108A1 (en) | 2008-05-09 | 2011-09-01 | The Regents Of The University Of California | Neuregulin/erbb signaling and integrin |
| JP5797112B2 (ja) | 2008-07-17 | 2015-10-21 | アコーダ セラピューティクス インコーポレイテッド | 心不全の治療または予防のためのニューレグリンまたはそのサブ配列の治療的投与方法 |
| US20110229444A1 (en) | 2008-11-28 | 2011-09-22 | Zensun (Shanghai) Science & Technology Limited | Neuregulin And Cardiac Stem Cells |
| EP2808339B1 (en) | 2008-11-28 | 2017-02-15 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Neuregulin peptides and their use |
| ES2748886T3 (es) | 2009-06-09 | 2020-03-18 | Zensun Shanghai Science & Tech Co Ltd | Métodos basados en Neuregulina para el tratamiento de la insuficiencia cardíaca |
| EP2440236B1 (en) | 2009-06-09 | 2016-05-04 | Zensun (Shanghai) Science and Technology Limited | Neuregulin based methods for treating heart failure |
| JP6096262B2 (ja) | 2009-08-25 | 2017-03-15 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー． | ニューレグリンに基づく心不全の治療方法 |
| CN102139095A (zh) | 2010-01-29 | 2011-08-03 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏缺血再灌注损伤的方法和组合物 |
| JP5890785B2 (ja) * | 2010-03-10 | 2016-03-22 | センプラ ファーマシューティカルズ，インコーポレイテッド | マクロライド抗生物質の非経口製剤 |
| WO2011119836A1 (en) | 2010-03-24 | 2011-09-29 | Massachusetts Institute Of Technology | Methods and compositions for cardioprotection and cardioregeneration |
| CN108420827A (zh) | 2010-07-22 | 2018-08-21 | 雷文制药有限公司 | 包含磁偶极子稳定化溶液的组合物及其用途 |
| CN102230084B (zh) * | 2011-06-14 | 2013-01-23 | 东北大学 | 低品位含砷难浸金矿的包覆生物氧化预处理方法 |
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun （Shanghai）Science & Technology Limited | Compositions and methods for treating heart failure |
| EP2834259A4 (en) * | 2012-04-02 | 2016-08-24 | Moderna Therapeutics Inc | MODIFIED POLYNUCLEOTIDES |
| CN109276705B (zh) | 2012-10-08 | 2023-10-20 | 上海泽生科技开发股份有限公司 | 治疗糖尿病患者心力衰竭的组份和方法 |
| US20160129084A1 (en) | 2013-03-06 | 2016-05-12 | Acorda Therapeutics, Inc. | Therapeutic Dosing of a Neuregulin or a Fragment Thereof for Treatment or Prophylaxis of Heart Failure |
| EP3610905B1 (en) | 2013-05-22 | 2021-03-31 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Extended release of neuregulin for treating heart failure |
| CN104337813A (zh) | 2013-07-23 | 2015-02-11 | 上海泽生科技开发有限公司 | 使用维生素b组合物促进胃肠系统动力的方法 |
| CN104758300A (zh) | 2014-01-02 | 2015-07-08 | 上海泽生科技开发有限公司 | 维生素d及其组合物的抗菌用途 |
| CN110946993A (zh) * | 2014-01-03 | 2020-04-03 | 上海泽生科技开发股份有限公司 | 纽兰格林制剂的配方 |
| CN105497876B (zh) | 2014-09-24 | 2021-01-15 | 上海泽生科技开发股份有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏室性心律失常的方法和组合物 |
| CN111407882A (zh) | 2014-10-17 | 2020-07-14 | 上海泽生科技开发股份有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
-
2014
- 2014-01-03 CN CN201911388095.8A patent/CN110946993A/zh active Pending
- 2014-01-03 CN CN201410002665.6A patent/CN104758922A/zh active Pending
- 2014-12-17 KR KR1020227021093A patent/KR102522140B1/ko active Active
- 2014-12-17 BR BR112016015660A patent/BR112016015660A2/pt not_active IP Right Cessation
- 2014-12-17 AU AU2014375637A patent/AU2014375637A1/en not_active Abandoned
- 2014-12-17 EP EP14876973.0A patent/EP3090756B2/en active Active
- 2014-12-17 KR KR1020237012378A patent/KR20230054749A/ko not_active Ceased
- 2014-12-17 CN CN201480071227.3A patent/CN105960248A/zh active Pending
- 2014-12-17 CA CA2935607A patent/CA2935607A1/en not_active Abandoned
- 2014-12-17 RU RU2016131667A patent/RU2738158C2/ru active
- 2014-12-17 US US15/109,583 patent/US10702585B2/en active Active
- 2014-12-17 WO PCT/CN2014/094073 patent/WO2015101182A1/zh not_active Ceased
- 2014-12-17 EP EP20195273.6A patent/EP3821904B1/en active Active
- 2014-12-17 CN CN201911390381.8A patent/CN111012898A/zh active Pending
- 2014-12-17 KR KR1020167020428A patent/KR20160105443A/ko not_active Ceased
- 2014-12-17 JP JP2016544419A patent/JP6703483B2/ja active Active
-
2020
- 2020-05-08 JP JP2020082456A patent/JP7100083B2/ja active Active
- 2020-06-05 US US16/894,540 patent/US11969458B2/en active Active
-
2022
- 2022-06-30 JP JP2022105452A patent/JP7479068B2/ja active Active
-
2024
- 2024-03-27 US US18/618,991 patent/US20250073306A1/en active Pending
- 2024-04-16 JP JP2024066182A patent/JP2024099628A/ja active Pending
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