JP2024037892A5 - - Google Patents

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Publication number
JP2024037892A5
JP2024037892A5 JP2023210859A JP2023210859A JP2024037892A5 JP 2024037892 A5 JP2024037892 A5 JP 2024037892A5 JP 2023210859 A JP2023210859 A JP 2023210859A JP 2023210859 A JP2023210859 A JP 2023210859A JP 2024037892 A5 JP2024037892 A5 JP 2024037892A5
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JP
Japan
Prior art keywords
compound
unsubstituted
substituted
hydrogen
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023210859A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024037892A (ja
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Publication date
Priority claimed from JP2023516136A external-priority patent/JP7406672B2/ja
Application filed filed Critical
Publication of JP2024037892A publication Critical patent/JP2024037892A/ja
Publication of JP2024037892A5 publication Critical patent/JP2024037892A5/ja
Pending legal-status Critical Current

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JP2023210859A 2021-08-10 2023-12-14 ニコチンアミド系ripk1阻害剤 Pending JP2024037892A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202163231590P 2021-08-10 2021-08-10
US63/231,590 2021-08-10
JP2023516136A JP7406672B2 (ja) 2021-08-10 2022-08-08 ニコチンアミド系ripk1阻害剤
PCT/US2022/039689 WO2023018643A1 (en) 2021-08-10 2022-08-08 Nicotinamide ripk1 inhibitors

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2023516136A Division JP7406672B2 (ja) 2021-08-10 2022-08-08 ニコチンアミド系ripk1阻害剤

Publications (2)

Publication Number Publication Date
JP2024037892A JP2024037892A (ja) 2024-03-19
JP2024037892A5 true JP2024037892A5 (cg-RX-API-DMAC10.html) 2025-08-18

Family

ID=83439074

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023516136A Active JP7406672B2 (ja) 2021-08-10 2022-08-08 ニコチンアミド系ripk1阻害剤
JP2023210859A Pending JP2024037892A (ja) 2021-08-10 2023-12-14 ニコチンアミド系ripk1阻害剤

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2023516136A Active JP7406672B2 (ja) 2021-08-10 2022-08-08 ニコチンアミド系ripk1阻害剤

Country Status (15)

Country Link
US (2) US11767310B2 (cg-RX-API-DMAC10.html)
EP (2) EP4643949A3 (cg-RX-API-DMAC10.html)
JP (2) JP7406672B2 (cg-RX-API-DMAC10.html)
KR (2) KR102707109B1 (cg-RX-API-DMAC10.html)
CN (1) CN117460722A (cg-RX-API-DMAC10.html)
AR (1) AR126733A1 (cg-RX-API-DMAC10.html)
AU (1) AU2022328136A1 (cg-RX-API-DMAC10.html)
BR (1) BR112023025850A2 (cg-RX-API-DMAC10.html)
CA (1) CA3219155A1 (cg-RX-API-DMAC10.html)
CO (1) CO2023017151A2 (cg-RX-API-DMAC10.html)
IL (1) IL308349A (cg-RX-API-DMAC10.html)
MX (1) MX2023014817A (cg-RX-API-DMAC10.html)
TW (1) TW202321211A (cg-RX-API-DMAC10.html)
WO (1) WO2023018643A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA202310682B (cg-RX-API-DMAC10.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202321211A (zh) 2021-08-10 2023-06-01 美商艾伯維有限公司 菸鹼醯胺ripk1抑制劑

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997005131A1 (en) 1995-08-02 1997-02-13 J. Uriach & Cia. S.A. New carboxamides with antifungal activity
US6218387B1 (en) 1996-12-20 2001-04-17 Hoechst Aktiengesellschaft Vitronectin receptor anatagonists, their preparation and their use
US6723727B1 (en) 1996-12-20 2004-04-20 Hoechst Aktiengesellschaft Substituted purine derivatives, processes for their preparation, their use, and compositions comprising them
CA2533889A1 (en) 2003-08-15 2005-03-03 Merck & Co., Inc. Mitotic kinesin inhibitors
US7465746B2 (en) 2003-08-15 2008-12-16 Merck & Co., Inc. Fluorinated 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP
US7112316B1 (en) 2005-08-08 2006-09-26 Uop Llc Process for preparing molecular sieves via continuous addition of nutrients
EP1984355A2 (en) 2006-02-16 2008-10-29 Takeda Pharmaceutical Company Limited Cyclic amine compound and use thereof for the prophylaxis or treatment of hypertension
ATE505454T1 (de) 2007-09-20 2011-04-15 Amgen Inc 1-(4-(4-benzylbenzamid)-benzyl)-azetidin-3- carboxylsäurederivate und entsprechende verbindungen als s1p-rezeptor-modulatoren zur behandlung von immunerkrankungen
AU2009225869B2 (en) 2008-03-18 2014-01-23 Merck Sharp & Dohme Llc Substituted 4-hydroxypyrimidine-5-carboxamides
WO2010120935A1 (en) 2009-04-15 2010-10-21 Abbott Laboratories Anti-viral compounds
WO2011113707A1 (en) 2010-03-17 2011-09-22 Exxonmobil Chemical Patents Inc. Plasticiser blends and compositions and articles made therefrom
CA2815131C (en) 2010-10-20 2020-06-09 Gruenenthal Gmbh Substituted 6-amino-nicotinamides as kcnq2/3 modulators
WO2013049255A1 (en) 2011-09-26 2013-04-04 Vanderbilt University Substitued 5-(prop-1-yn-1-yl)picolinamide analogs as allosteric modulators of mglur5 receptors
TWI648274B (zh) 2013-02-15 2019-01-21 英商葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之雜環醯胺類 (二)
EA032355B1 (ru) 2013-12-24 2019-05-31 Онкотартис, Инк. Бензамидные и никотинамидные соединения и способы их применения
KR101555033B1 (ko) 2014-07-28 2015-09-23 충남대학교산학협력단 신규한 메타논 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 망막 질환의 예방 또는 치료용 약학적 조성물
KR101551313B1 (ko) 2014-07-28 2015-09-09 충남대학교산학협력단 신규한 인덴 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 망막 질환의 예방 또는 치료용 약학적 조성물
RU2017109122A (ru) 2014-08-21 2018-09-21 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Способы лечения с использованием гетероциклических амидов в качестве ингибиторов киназы
EP3224237B1 (en) 2014-12-24 2024-09-11 National Institute Of Biological Sciences, Beijing Necrosis inhibitors
UY36680A (es) 2015-05-19 2016-12-30 Glaxosmithkline Ip Dev Ltd Amidas heterocíclicas como inhibidores de quinasa
RU2716136C2 (ru) 2015-07-02 2020-03-06 Ф. Хоффманн-Ля Рош Аг Бициклические лактамы и способы их применения
WO2017069279A1 (ja) 2015-10-23 2017-04-27 武田薬品工業株式会社 複素環化合物
CN108602809B (zh) 2015-12-04 2022-09-30 戴纳立制药公司 异噁唑烷衍生的受体相互作用蛋白激酶1(ripk 1)的抑制剂
US10961258B2 (en) 2015-12-21 2021-03-30 Glaxosmithkline Intellectual Property Development Limited Heterocyclic amides as kinase inhibitors
US9815850B2 (en) 2016-02-05 2017-11-14 Denali Therapeutics Inc. Compounds, compositions and methods
EP3515447A4 (en) 2016-09-26 2020-05-27 Tufts University Uridine nucleoside derivatives, compositions and methods of use
LT3580220T (lt) 2017-02-13 2021-12-27 Bristol-Myers Squibb Company Aminotriazolopiridinai, kaip kinazės inhibitoriai
DE102017211104B3 (de) 2017-06-29 2018-10-18 Bundesdruckerei Gmbh Verfahren und Vorrichtung zum Verifizieren eines elektrolumineszierenden Sicherheitsmerkmals in einem Wert- oder Sicherheitsdokument unter Ausnutzung von zusätzlicher Lichtstrahlung
CN111566103B (zh) * 2017-10-30 2023-06-23 百时美施贵宝公司 作为激酶抑制剂的氨基咪唑并吡嗪
US11618753B2 (en) * 2018-01-26 2023-04-04 Bristol-Myers Squibb Company Aminopyrrolotriazines as kinase inhibitors
SI3788044T1 (sl) 2018-05-03 2023-12-29 Rigel Pharmaceuticals, Inc. Spojine, ki zavirajo RIP1 in postopki za njihovo izdelavo in uporabo
WO2020007234A1 (zh) * 2018-07-02 2020-01-09 深圳市塔吉瑞生物医药有限公司 用于抑制蛋白激酶活性的炔基(杂)芳环类化合物
WO2020013531A1 (ko) 2018-07-10 2020-01-16 보로노이바이오 주식회사 N-(3-(이미다조[1,2-b]피리다진-3-일에티닐)-4-메틸페닐)-5-페닐-4,5-다이하이드로-1H-피라졸-1-카복사마이드 유도체 및 이를 유효성분으로 포함하는 키나아제 관련 질환 치료용 약학적 조성물
WO2020149553A1 (ko) * 2019-01-15 2020-07-23 주식회사 보로노이 아릴 또는 헤테로아릴 유도체, 및 이를 유효성분으로 포함하는 키나아제 관련 질환 치료용 약학적 조성물
TW202321211A (zh) 2021-08-10 2023-06-01 美商艾伯維有限公司 菸鹼醯胺ripk1抑制劑

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