JP2023553869A - ディッシュでの器官形成を促進するオルガノイド培養のエンジニアリング - Google Patents
ディッシュでの器官形成を促進するオルガノイド培養のエンジニアリング Download PDFInfo
- Publication number
- JP2023553869A JP2023553869A JP2023533796A JP2023533796A JP2023553869A JP 2023553869 A JP2023553869 A JP 2023553869A JP 2023533796 A JP2023533796 A JP 2023533796A JP 2023533796 A JP2023533796 A JP 2023533796A JP 2023553869 A JP2023553869 A JP 2023553869A
- Authority
- JP
- Japan
- Prior art keywords
- culture
- organoids
- organoid
- octopus
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/22—Transparent or translucent parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/14—Scaffolds; Matrices
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063121684P | 2020-12-04 | 2020-12-04 | |
| US63/121,684 | 2020-12-04 | ||
| PCT/US2021/072762 WO2022120391A1 (en) | 2020-12-04 | 2021-12-06 | Engineering of organoid culture for enhanced organogenesis in a dish |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023553869A true JP2023553869A (ja) | 2023-12-26 |
| JPWO2022120391A5 JPWO2022120391A5 (https=) | 2024-12-03 |
| JP2023553869A5 JP2023553869A5 (https=) | 2024-12-03 |
Family
ID=81853593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023533796A Pending JP2023553869A (ja) | 2020-12-04 | 2021-12-06 | ディッシュでの器官形成を促進するオルガノイド培養のエンジニアリング |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240026261A1 (https=) |
| EP (1) | EP4256027A4 (https=) |
| JP (1) | JP2023553869A (https=) |
| CN (1) | CN116490603A (https=) |
| AU (1) | AU2021390584A1 (https=) |
| CA (1) | CA3197769A1 (https=) |
| WO (1) | WO2022120391A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120225651A (zh) * | 2022-11-21 | 2025-06-27 | 康宁公司 | 具有保持结构的微板及其使用方法 |
| WO2025041139A1 (en) * | 2023-08-23 | 2025-02-27 | Quris Technologies Ltd. | Fluidic multi well systems and methods of using the same for culturing organoids |
| WO2025087283A1 (zh) * | 2023-10-23 | 2025-05-01 | 江苏艾玮得生物科技有限公司 | 血管化类器官球聚体模型的构建方法、血管化类器官球聚体模型及其应用 |
| CN117448276A (zh) * | 2023-12-06 | 2024-01-26 | 复旦大学附属妇产科医院 | 一种宫颈癌血管化类器官的制备方法 |
| EP4613841A1 (en) * | 2024-03-04 | 2025-09-10 | Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universität Tübingen | Microwell for culturing an organoid and device for measuring electrical activity and/or stimulating cells in a three-dimensional network |
| WO2025202125A1 (en) * | 2024-03-28 | 2025-10-02 | F. Hoffmann-La Roche Ag | Cell culturing device |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011528653A (ja) * | 2008-06-04 | 2011-11-24 | ウヴェ・マルクス | オンチップ臓器デバイス |
| JP2019517277A (ja) * | 2016-06-03 | 2019-06-24 | ゲオルグ−オーガスト−ユニバースィタット ゴッティンゲン スティフタング オッフェントリシェン リシュツ,ユニヴァースィタットスメディズィン | 孔付プレート |
| JP2020523020A (ja) * | 2017-06-13 | 2020-08-06 | フラウンホファー ゲセルシャフト ツール フェールデルンク ダー アンゲヴァンテン フォルシュンク エー.ファオ. | 細胞を培養するための装置及び方法 |
| JP2020115781A (ja) * | 2019-01-23 | 2020-08-06 | ウシオ電機株式会社 | 細胞培養チップ |
| WO2020157697A1 (en) * | 2019-01-30 | 2020-08-06 | Stemnovate Limited | Method and apparatus for real time monitoring of cell and tissue culture |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI509067B (zh) * | 2014-04-10 | 2015-11-21 | Nat Univ Tsing Hua | 體外細胞自動抓取共養平台系統 |
| US11692160B2 (en) * | 2016-11-10 | 2023-07-04 | The Asan Foundation | Microfluidic chip, three-dimensional channel structure, cell culture method using same, and activity evaluation method of bioactive substance using same |
| WO2018175478A2 (en) * | 2017-03-21 | 2018-09-27 | Massachusetts Institute Of Technology | Modular organ microphysiological system with microbiome |
| KR102083083B1 (ko) * | 2018-06-21 | 2020-02-28 | 연세대학교 산학협력단 | 고효율 오가노이드 배양 디바이스 및 배양 시스템 |
-
2021
- 2021-12-06 CA CA3197769A patent/CA3197769A1/en active Pending
- 2021-12-06 WO PCT/US2021/072762 patent/WO2022120391A1/en not_active Ceased
- 2021-12-06 AU AU2021390584A patent/AU2021390584A1/en active Pending
- 2021-12-06 EP EP21901670.6A patent/EP4256027A4/en active Pending
- 2021-12-06 CN CN202180080345.0A patent/CN116490603A/zh active Pending
- 2021-12-06 US US18/255,398 patent/US20240026261A1/en active Pending
- 2021-12-06 JP JP2023533796A patent/JP2023553869A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011528653A (ja) * | 2008-06-04 | 2011-11-24 | ウヴェ・マルクス | オンチップ臓器デバイス |
| JP2019517277A (ja) * | 2016-06-03 | 2019-06-24 | ゲオルグ−オーガスト−ユニバースィタット ゴッティンゲン スティフタング オッフェントリシェン リシュツ,ユニヴァースィタットスメディズィン | 孔付プレート |
| JP2020523020A (ja) * | 2017-06-13 | 2020-08-06 | フラウンホファー ゲセルシャフト ツール フェールデルンク ダー アンゲヴァンテン フォルシュンク エー.ファオ. | 細胞を培養するための装置及び方法 |
| JP2020115781A (ja) * | 2019-01-23 | 2020-08-06 | ウシオ電機株式会社 | 細胞培養チップ |
| WO2020157697A1 (en) * | 2019-01-30 | 2020-08-06 | Stemnovate Limited | Method and apparatus for real time monitoring of cell and tissue culture |
Non-Patent Citations (1)
| Title |
|---|
| ADVANCED MATERIALS, vol. 32, JPN6026000422, 1 October 2020 (2020-10-01), pages 1 - 12, ISSN: 0005775167 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4256027A4 (en) | 2026-03-18 |
| EP4256027A1 (en) | 2023-10-11 |
| CA3197769A1 (en) | 2022-06-09 |
| US20240026261A1 (en) | 2024-01-25 |
| CN116490603A (zh) | 2023-07-25 |
| WO2022120391A1 (en) | 2022-06-09 |
| AU2021390584A1 (en) | 2023-06-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Park et al. | Geometric engineering of organoid culture for enhanced organogenesis in a dish | |
| JP2023553869A (ja) | ディッシュでの器官形成を促進するオルガノイド培養のエンジニアリング | |
| Lovett et al. | Innovations in 3D tissue models of human brain physiology and diseases | |
| Mittal et al. | Organ‐on‐chip models: implications in drug discovery and clinical applications | |
| Sudo et al. | Transport-mediated angiogenesis in 3D epithelial coculture | |
| Lee et al. | Design and fabrication of human skin by three-dimensional bioprinting | |
| Tanimizu et al. | Liver progenitor cells develop cholangiocyte-type epithelial polarity in three-dimensional culture | |
| EP2970896B1 (en) | Engineered liver tissues, arrays thereof, and methods of making the same | |
| CN115812008A (zh) | 微流控芯片及使用其的微生理系统 | |
| Lacombe et al. | Plant-based scaffolds modify cellular response to drug and radiation exposure compared to standard cell culture models | |
| Torrejon et al. | Recreating a human trabecular meshwork outflow system on microfabricated porous structures | |
| Valverde et al. | Biomimetic models of the glomerulus | |
| US20200115667A1 (en) | Vascularized microfluidic platforms | |
| Son et al. | Engineering tissue‐specific, multiscale microvasculature with a capillary network for prevascularized tissue | |
| JP2017518070A (ja) | 人工的な三次元の乳房組織、脂肪組織、および腫瘍疾患モデル | |
| Tan et al. | Human fibroblast-macrophage tissue spheroids demonstrate ratio-dependent fibrotic activity for in vitro fibrogenesis model development | |
| CN103415616A (zh) | 肿瘤细胞和组织培养物 | |
| Soon et al. | A human model of arteriovenous malformation (AVM)-on-a-chip reproduces key disease hallmarks and enables drug testing in perfused human vessel networks | |
| Tao et al. | Organoid‐guided precision medicine: from bench to bedside | |
| CN101451105B (zh) | 一种毛细血管模型的构建方法及其微系统芯片 | |
| Donzanti et al. | Stochastic to deterministic: A straightforward approach to create serially perfusable multiscale capillary beds | |
| Wang et al. | Diffusion-based culture and real-time impedance monitoring of tumor spheroids in hydrogel microwells of a suspended membrane under microfluidic conditions | |
| Shin | Modeling perfusable human brain microvasculature: Multimodal investigation of cerebrovasculature in dementia, trauma and development. | |
| Li | Development of a Vascularized Heart-on-a-chip for studying the impact of endothelial cells in cardiac homeostasis and disease modeling | |
| 서수영 | Development of microphysiological system of human blood-brain barrier to study brain pathology |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20241125 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20241125 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20251210 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20260120 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20260417 |