JP2023552610A5 - - Google Patents
Info
- Publication number
- JP2023552610A5 JP2023552610A5 JP2023535475A JP2023535475A JP2023552610A5 JP 2023552610 A5 JP2023552610 A5 JP 2023552610A5 JP 2023535475 A JP2023535475 A JP 2023535475A JP 2023535475 A JP2023535475 A JP 2023535475A JP 2023552610 A5 JP2023552610 A5 JP 2023552610A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- compounds
- compound
- camptothecin derivative
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011463704.4 | 2020-12-11 | ||
| CN202011463704 | 2020-12-11 | ||
| PCT/CN2021/136769 WO2022121981A1 (zh) | 2020-12-11 | 2021-12-09 | 新型喜树碱衍生物、含其的组合物和其用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023552610A JP2023552610A (ja) | 2023-12-18 |
| JP2023552610A5 true JP2023552610A5 (enExample) | 2026-01-16 |
Family
ID=81974225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023535475A Pending JP2023552610A (ja) | 2020-12-11 | 2021-12-09 | 新規カンプトテシン誘導体、それを含む組成物およびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230416270A1 (enExample) |
| EP (1) | EP4265620A4 (enExample) |
| JP (1) | JP2023552610A (enExample) |
| KR (1) | KR20230118891A (enExample) |
| CN (1) | CN116583526B (enExample) |
| AU (1) | AU2021394411A1 (enExample) |
| CA (1) | CA3200649A1 (enExample) |
| MX (1) | MX2023006751A (enExample) |
| WO (1) | WO2022121981A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102630719B1 (ko) * | 2022-07-11 | 2024-01-30 | 주식회사 피노바이오 | Ddx5 단백질에 결합하는 캄토테신 유도체 및 이의 프로드럭 |
| EP4538276A1 (en) * | 2022-07-11 | 2025-04-16 | Pinotbio, Inc. | Ddx5 protein-binding camptothecin derivatives and prodrugs thereof |
| WO2024208314A1 (zh) * | 2023-04-07 | 2024-10-10 | 长春金赛药业有限责任公司 | 喜树碱衍生物、药物组合物及其制备方法和应用 |
| KR20250057677A (ko) * | 2023-10-19 | 2025-04-29 | (주)셀트리온 | 캄프토테신 유도체를 포함하는 항-Nectin-4 항체-약물 접합체 |
| WO2025084851A1 (ko) * | 2023-10-19 | 2025-04-24 | (주)셀트리온 | 캄프토테신 유도체를 포함하는 항-c-met 항체-약물 접합체 |
| KR20250057675A (ko) * | 2023-10-19 | 2025-04-29 | (주)셀트리온 | 캄프토테신 유도체를 포함하는 항-Tissue factor 항체-약물 접합체 |
| WO2025261469A1 (zh) * | 2024-06-20 | 2025-12-26 | 科霸生物（江苏）有限公司 | 喜树碱衍生物、抗体、药物偶联物、及其组合物和应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3008226B2 (ja) * | 1991-01-16 | 2000-02-14 | 第一製薬株式会社 | 六環性化合物 |
| JP3359955B2 (ja) * | 1992-07-16 | 2002-12-24 | 第一製薬株式会社 | 抗腫瘍剤 |
| DE19640207A1 (de) * | 1996-09-30 | 1998-04-02 | Bayer Ag | Glycokonjugate von modifizierten Camptothecin-Derivaten (A- oder B-Ring-Verknüpfung) |
| JP2000044567A (ja) * | 1998-07-29 | 2000-02-15 | Dai Ichi Seiyaku Co Ltd | 六環性化合物 |
| IL310627B2 (en) * | 2014-01-31 | 2026-04-01 | Daiichi Sankyo Co Ltd | Anti-HER2 antibody-drug conjugates, compositions containing them and uses thereof |
| EP3130608B1 (en) * | 2014-04-10 | 2019-09-04 | Daiichi Sankyo Co., Ltd. | (anti-her2 antibody)-drug conjugate |
| KR20190066026A (ko) * | 2016-10-07 | 2019-06-12 | 다이이찌 산쿄 가부시키가이샤 | 항 her2 항체-약물 콘주게이트 투여에 의한 내성암의 치료 |
| SG11202100653YA (en) * | 2018-07-25 | 2021-02-25 | Daiichi Sankyo Co Ltd | Effective method for manufacturing antibody-drug conjugate |
| WO2020063676A1 (zh) * | 2018-09-26 | 2020-04-02 | 江苏恒瑞医药股份有限公司 | 依喜替康类似物的配体-药物偶联物及其制备方法和应用 |
| CA3114474A1 (en) * | 2018-09-30 | 2020-04-02 | Jiangsu Hengrui Medicine Co., Ltd. | Anti-b7h3 antibody-exatecan analog conjugate and medicinal use thereof |
| CN111689980A (zh) * | 2019-05-26 | 2020-09-22 | 四川百利药业有限责任公司 | 一种喜树碱药物及其抗体偶联物 |
| CN113766933B (zh) * | 2019-06-28 | 2024-09-06 | 上海复旦张江生物医药股份有限公司 | 一种抗体偶联药物、其中间体、制备方法及应用 |
| WO2022171115A1 (zh) * | 2021-02-09 | 2022-08-18 | 微境生物医药科技(上海)有限公司 | 用于adc制备的喜树碱衍生物 |
-
2021
- 2021-12-09 CN CN202180082581.6A patent/CN116583526B/zh active Active
- 2021-12-09 JP JP2023535475A patent/JP2023552610A/ja active Pending
- 2021-12-09 WO PCT/CN2021/136769 patent/WO2022121981A1/zh not_active Ceased
- 2021-12-09 MX MX2023006751A patent/MX2023006751A/es unknown
- 2021-12-09 CA CA3200649A patent/CA3200649A1/en active Pending
- 2021-12-09 US US18/039,229 patent/US20230416270A1/en active Pending
- 2021-12-09 KR KR1020237022556A patent/KR20230118891A/ko active Pending
- 2021-12-09 EP EP21902686.1A patent/EP4265620A4/en active Pending
- 2021-12-09 AU AU2021394411A patent/AU2021394411A1/en active Pending
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