JP2023552610A5 - - Google Patents
Info
- Publication number
- JP2023552610A5 JP2023552610A5 JP2023535475A JP2023535475A JP2023552610A5 JP 2023552610 A5 JP2023552610 A5 JP 2023552610A5 JP 2023535475 A JP2023535475 A JP 2023535475A JP 2023535475 A JP2023535475 A JP 2023535475A JP 2023552610 A5 JP2023552610 A5 JP 2023552610A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- compounds
- compound
- camptothecin derivative
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011463704 | 2020-12-11 | ||
| CN202011463704.4 | 2020-12-11 | ||
| PCT/CN2021/136769 WO2022121981A1 (zh) | 2020-12-11 | 2021-12-09 | 新型喜树碱衍生物、含其的组合物和其用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023552610A JP2023552610A (ja) | 2023-12-18 |
| JP2023552610A5 true JP2023552610A5 (enExample) | 2026-01-16 |
Family
ID=81974225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023535475A Pending JP2023552610A (ja) | 2020-12-11 | 2021-12-09 | 新規カンプトテシン誘導体、それを含む組成物およびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230416270A1 (enExample) |
| EP (1) | EP4265620A4 (enExample) |
| JP (1) | JP2023552610A (enExample) |
| KR (1) | KR20230118891A (enExample) |
| CN (1) | CN116583526B (enExample) |
| AU (1) | AU2021394411A1 (enExample) |
| CA (1) | CA3200649A1 (enExample) |
| MX (1) | MX2023006751A (enExample) |
| WO (1) | WO2022121981A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240008280A (ko) * | 2022-07-11 | 2024-01-18 | 주식회사 피노바이오 | Ddx5 단백질에 결합하는 캄토테신 유도체 및 이의 프로드럭 |
| KR102630719B1 (ko) * | 2022-07-11 | 2024-01-30 | 주식회사 피노바이오 | Ddx5 단백질에 결합하는 캄토테신 유도체 및 이의 프로드럭 |
| EP4692091A1 (en) * | 2023-04-07 | 2026-02-11 | Changchun Genescience Pharmaceutical Co., Ltd. | Camptothecin derivative, and pharmaceutical composition, preparation method therefor and use thereof |
| CN122295130A (zh) * | 2023-10-19 | 2026-06-26 | 赛特瑞恩股份有限公司 | 包含喜树碱衍生物的抗c-met抗体-药物缀合物 |
| KR20250057677A (ko) * | 2023-10-19 | 2025-04-29 | (주)셀트리온 | 캄프토테신 유도체를 포함하는 항-Nectin-4 항체-약물 접합체 |
| CN122295131A (zh) * | 2023-10-19 | 2026-06-26 | 赛特瑞恩股份有限公司 | 包含喜树碱衍生物的抗组织因子抗体-药物缀合物 |
| CN122374343A (zh) | 2023-11-30 | 2026-07-10 | 江苏康宁杰瑞生物制药有限公司 | 包含pd-l1结合分子与双特异性抗体-药物偶联物的组合物及其用途 |
| AU2024415931A1 (en) | 2023-12-27 | 2026-07-16 | Jiangsu Alphamab Biopharmaceuticals Co., Ltd. | Multi-specific antibody targeting her3 and trop2 and conjugate thereof |
| WO2025261469A1 (zh) * | 2024-06-20 | 2025-12-26 | 科霸生物（江苏）有限公司 | 喜树碱衍生物、抗体、药物偶联物、及其组合物和应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3008226B2 (ja) * | 1991-01-16 | 2000-02-14 | 第一製薬株式会社 | 六環性化合物 |
| JP3359955B2 (ja) * | 1992-07-16 | 2002-12-24 | 第一製薬株式会社 | 抗腫瘍剤 |
| DE19640207A1 (de) * | 1996-09-30 | 1998-04-02 | Bayer Ag | Glycokonjugate von modifizierten Camptothecin-Derivaten (A- oder B-Ring-Verknüpfung) |
| JP2000044567A (ja) * | 1998-07-29 | 2000-02-15 | Dai Ichi Seiyaku Co Ltd | 六環性化合物 |
| SG11201603960XA (en) * | 2014-01-31 | 2016-07-28 | Daiichi Sankyo Co Ltd | Anti-her2 antibody-drug conjugate |
| US11185594B2 (en) * | 2014-04-10 | 2021-11-30 | Daiichi Sankyo Company, Limited | (Anti-HER2 antibody)-drug conjugate |
| WO2018066626A1 (ja) * | 2016-10-07 | 2018-04-12 | 第一三共株式会社 | 抗ｈｅｒ２抗体－薬物コンジュゲート投与による耐性癌の治療 |
| SG11202100653YA (en) * | 2018-07-25 | 2021-02-25 | Daiichi Sankyo Co Ltd | Effective method for manufacturing antibody-drug conjugate |
| UA130338C2 (uk) * | 2018-09-26 | 2026-01-28 | Джянгсу Хенгруй Медісін Ко., Лтд. | Кон'югат ліганд-лікарський засіб аналога ексатекану, спосіб його отримання та його застосування |
| JP7408646B2 (ja) * | 2018-09-30 | 2024-01-05 | ジエンス ハンソー ファーマスーティカル グループ カンパニー リミテッド | 抗－ｂ７ｈ３抗体－エキサテカンアナログコンジュゲート及びその医薬用途 |
| CN111689980A (zh) * | 2019-05-26 | 2020-09-22 | 四川百利药业有限责任公司 | 一种喜树碱药物及其抗体偶联物 |
| WO2020259258A1 (zh) * | 2019-06-28 | 2020-12-30 | 上海复旦张江生物医药股份有限公司 | 一种抗体偶联药物、其中间体、制备方法及应用 |
| WO2022171115A1 (zh) * | 2021-02-09 | 2022-08-18 | 微境生物医药科技(上海)有限公司 | 用于adc制备的喜树碱衍生物 |
-
2021
- 2021-12-09 AU AU2021394411A patent/AU2021394411A1/en active Pending
- 2021-12-09 CN CN202180082581.6A patent/CN116583526B/zh active Active
- 2021-12-09 MX MX2023006751A patent/MX2023006751A/es unknown
- 2021-12-09 WO PCT/CN2021/136769 patent/WO2022121981A1/zh not_active Ceased
- 2021-12-09 JP JP2023535475A patent/JP2023552610A/ja active Pending
- 2021-12-09 KR KR1020237022556A patent/KR20230118891A/ko active Pending
- 2021-12-09 CA CA3200649A patent/CA3200649A1/en active Pending
- 2021-12-09 US US18/039,229 patent/US20230416270A1/en active Pending
- 2021-12-09 EP EP21902686.1A patent/EP4265620A4/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024050527A5 (enExample) | ||
| JP2014503574A5 (enExample) | ||
| JP2022545633A5 (enExample) | ||
| JP2011509309A5 (enExample) | ||
| RU2005107314A (ru) | Пиримидопроизводные, характеризующиеся антипролиферативной активностью | |
| JP2014511892A5 (enExample) | ||
| JP2011519854A5 (enExample) | ||
| JP2004516314A5 (enExample) | ||
| JP2010540508A5 (enExample) | ||
| AR037329A1 (es) | Compuestos pirazolo pirimidinona, procedimientos para la preparacion de los mismos, composiciones farmaceuticas de los mismos y usos de los mismos en la preparacion de medicamentos | |
| JP2022510925A5 (enExample) | ||
| JP2011529054A5 (enExample) | ||
| JP2014511891A5 (enExample) | ||
| JP2006514626A5 (enExample) | ||
| ATE512961T1 (de) | Amorphes nebivolol hydrochlorid und seine herstellung | |
| JP2007520440A5 (enExample) | ||
| RU2008152763A (ru) | Применение агонистов каннабиноидного рецептора в качестве индуцирующих гипотермию лекарственных средств для лечения ишемии | |
| RU2011133128A (ru) | Противоопухолевые соединения дигидропиран-2-она | |
| JP2003508524A5 (enExample) | ||
| JP2022529309A5 (enExample) | ||
| JP2010535706A5 (enExample) | ||
| JP2004523478A5 (enExample) | ||
| RU2007116987A (ru) | Новые соединения | |
| RU2007122406A (ru) | Производные тетралина и индана и их применения в качестве антагонистов 5-нт | |
| JP2021503451A5 (enExample) |