JP2023546224A5 - - Google Patents

Info

Publication number
JP2023546224A5
JP2023546224A5 JP2023524306A JP2023524306A JP2023546224A5 JP 2023546224 A5 JP2023546224 A5 JP 2023546224A5 JP 2023524306 A JP2023524306 A JP 2023524306A JP 2023524306 A JP2023524306 A JP 2023524306A JP 2023546224 A5 JP2023546224 A5 JP 2023546224A5
Authority
JP
Japan
Prior art keywords
chloro
fluorophenoxy
piperidine
acetamide
carboxylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023524306A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023546224A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/079208 external-priority patent/WO2022084446A1/en
Publication of JP2023546224A publication Critical patent/JP2023546224A/ja
Publication of JP2023546224A5 publication Critical patent/JP2023546224A5/ja
Pending legal-status Critical Current

Links

JP2023524306A 2020-10-22 2021-10-21 統合ストレス応答経路のモジュレーター Pending JP2023546224A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20203312.2 2020-10-22
EP20203312 2020-10-22
PCT/EP2021/079208 WO2022084446A1 (en) 2020-10-22 2021-10-21 Modulators of the integrated stress response pathway

Publications (2)

Publication Number Publication Date
JP2023546224A JP2023546224A (ja) 2023-11-01
JP2023546224A5 true JP2023546224A5 (https=) 2024-10-28

Family

ID=73013230

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023524306A Pending JP2023546224A (ja) 2020-10-22 2021-10-21 統合ストレス応答経路のモジュレーター

Country Status (10)

Country Link
US (1) US20230391725A1 (https=)
EP (1) EP4232153A1 (https=)
JP (1) JP2023546224A (https=)
KR (1) KR20230110511A (https=)
CN (1) CN117098753A (https=)
AU (1) AU2021367147B2 (https=)
CA (1) CA3195290A1 (https=)
IL (1) IL302170A (https=)
MX (1) MX2023004626A (https=)
WO (1) WO2022084446A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022011143A (es) 2020-03-11 2022-10-13 Evotec Int Gmbh Moduladores de la via de respuesta integrada al estres.
MX2023004623A (es) * 2020-10-22 2023-05-12 Evotec Int Gmbh Moduladores de la via integrada de respuesta al estres.

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6806562B2 (ja) 2013-03-15 2021-01-06 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア eIF2α経路の調節因子
TWI763668B (zh) 2016-05-05 2022-05-11 美商嘉來克生命科學有限責任公司 整合應激途徑之調節劑
TW201808903A (zh) * 2016-05-05 2018-03-16 嘉來克生命科學有限責任公司 整合應激途徑之調節劑
TW201808888A (zh) 2016-05-05 2018-03-16 嘉來克生命科學有限責任公司 整合應激途徑之調節劑
TW201808914A (zh) 2016-05-05 2018-03-16 嘉來克生命科學有限責任公司 整合應激途徑之調節劑
AU2017279027A1 (en) 2016-06-08 2018-12-20 Glaxosmithkline Intellectual Property Development Limited Chemical Compounds
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DK3676297T3 (da) 2017-09-01 2023-08-14 Denali Therapeutics Inc Forbindelser, sammensætninger og fremgangsmåder
UY37957A (es) 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
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CA3080804A1 (en) 2017-11-02 2019-05-09 Calico Life Sciences Llc Modulators of the integrated stress pathway
UY37956A (es) 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
EP3704098B1 (en) 2017-11-02 2024-01-24 Calico Life Sciences LLC Modulators of the integrated stress pathway
UY37958A (es) 2017-11-02 2019-05-31 Abbvie Inc Moduladores de la vía de estrés integrada
EP3704125B1 (en) * 2017-11-02 2026-03-11 Calico Life Sciences LLC Modulators of the integrated stress pathway
SG11202004009TA (en) 2017-11-02 2020-05-28 Calico Life Sciences Llc Modulators of the integrated stress pathway
EP3704096B1 (en) 2017-11-02 2026-04-22 Calico Life Sciences LLC Modulators of the integrated stress pathway
WO2019118785A2 (en) 2017-12-13 2019-06-20 Praxis Biotech LLC Inhibitors of integrated stress response pathway
WO2019183589A1 (en) 2018-03-23 2019-09-26 Denali Therapeutics Inc. Modulators of eukaryotic initiation factor 2
WO2019193540A1 (en) 2018-04-06 2019-10-10 Glaxosmithkline Intellectual Property Development Limited Heteroaryl derivatives of formula (i) as atf4 inhibitors
WO2019193541A1 (en) 2018-04-06 2019-10-10 Glaxosmithkline Intellectual Property Development Limited Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors
WO2019236710A1 (en) * 2018-06-05 2019-12-12 Praxis Biotech LLC Inhibitors of integrated stress response pathway
JP2021529814A (ja) 2018-07-09 2021-11-04 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 化学化合物
WO2020031107A1 (en) 2018-08-08 2020-02-13 Glaxosmithkline Intellectual Property Development Limited Chemical compounds
TWI877863B (zh) 2018-10-11 2025-03-21 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
MA54953A (fr) 2019-02-13 2021-12-22 Denali Therapeutics Inc Composés, compositions et procédés
US12091392B2 (en) 2019-02-13 2024-09-17 Denali Therapeutics Inc. Compounds, compositions and methods
US20200270232A1 (en) 2019-02-25 2020-08-27 Praxis Biotech LLC Inhibitors of integrated stress response pathway
US20220177456A1 (en) 2019-03-06 2022-06-09 Denali Therapeutics Inc. Compounds, compositions and methods
MX2021012904A (es) 2019-04-23 2022-01-18 Evotec Int Gmbh Moduladores de la via de respuesta al estres integrada.
CA3137213A1 (en) 2019-04-23 2020-10-29 Evotec International Gmbh Modulators of the integrated stress response pathway
AR118836A1 (es) 2019-04-30 2021-11-03 Calico Life Sciences Llc Moduladores de la vía de tensión integrada
MX2021013197A (es) * 2019-04-30 2022-02-24 Calico Life Sciences Llc Cicloalquilos sustituidos como moduladores de la vía integrada del estrés.
MX2021015210A (es) 2019-06-12 2022-01-18 Praxis Biotech LLC Inhibidores de la via de respuesta al estres integrada.
JP2022536663A (ja) 2019-06-12 2022-08-18 プラクシス バイオテック エルエルシー 統合的ストレス応答経路のモジュレーター
AU2021213289A1 (en) 2020-01-28 2022-07-07 Evotec International Gmbh Modulators of the integrated stress response pathway
MX2022011143A (es) 2020-03-11 2022-10-13 Evotec Int Gmbh Moduladores de la via de respuesta integrada al estres.

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