JP2021511363A5 - - Google Patents
Info
- Publication number
- JP2021511363A5 JP2021511363A5 JP2020540798A JP2020540798A JP2021511363A5 JP 2021511363 A5 JP2021511363 A5 JP 2021511363A5 JP 2020540798 A JP2020540798 A JP 2020540798A JP 2020540798 A JP2020540798 A JP 2020540798A JP 2021511363 A5 JP2021511363 A5 JP 2021511363A5
- Authority
- JP
- Japan
- Prior art keywords
- triazine
- amino
- pyrrolo
- trifluoromethyl
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862622415P | 2018-01-26 | 2018-01-26 | |
| US62/622,415 | 2018-01-26 | ||
| PCT/US2019/014918 WO2019147782A1 (en) | 2018-01-26 | 2019-01-24 | Aminopyrrolotriazines as kinase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021511363A JP2021511363A (ja) | 2021-05-06 |
| JP2021511363A5 true JP2021511363A5 (https=) | 2022-01-28 |
| JP7307734B2 JP7307734B2 (ja) | 2023-07-12 |
Family
ID=65363405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020540798A Active JP7307734B2 (ja) | 2018-01-26 | 2019-01-24 | キナーゼ阻害剤としてのアミノピロロトリアジン |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US11618753B2 (https=) |
| EP (1) | EP3743430B1 (https=) |
| JP (1) | JP7307734B2 (https=) |
| KR (1) | KR102759231B1 (https=) |
| CN (1) | CN112262139B (https=) |
| AR (1) | AR114186A1 (https=) |
| AU (1) | AU2019211382B2 (https=) |
| BR (1) | BR112020014516A2 (https=) |
| CA (1) | CA3088548A1 (https=) |
| EA (1) | EA202091777A1 (https=) |
| ES (1) | ES2959399T3 (https=) |
| IL (1) | IL276269A (https=) |
| MX (1) | MX2020007531A (https=) |
| SG (1) | SG11202007035YA (https=) |
| TW (1) | TW201940485A (https=) |
| WO (1) | WO2019147782A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3580220B1 (en) | 2017-02-13 | 2021-11-17 | Bristol-Myers Squibb Company | Aminotriazolopyridines as kinase inhibitors |
| DK3704118T3 (da) | 2017-10-30 | 2022-03-14 | Bristol Myers Squibb Co | Aminoimidazopyrazin som kinasehæmmere |
| EP3849969B1 (en) | 2018-09-13 | 2023-04-19 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| EP3849968B1 (en) | 2018-09-13 | 2022-12-21 | Bristol-Myers Squibb Company | 1h-indazole carboxamides as receptor-interacting protein kinase 1 inhibitors (ripk1) |
| WO2021067654A1 (en) | 2019-10-03 | 2021-04-08 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| KR20220139947A (ko) * | 2020-02-07 | 2022-10-17 | 샌트랄 글래스 컴퍼니 리미티드 | 경화성 조성물, 경화물, 전자 디바이스, 표시 장치, 광학 부재, 중합체, 감광성 조성물, 패턴 및 화합물 |
| WO2022007921A1 (zh) * | 2020-07-10 | 2022-01-13 | 北京范恩柯尔生物科技有限公司 | 三嗪类化合物及其组合物和用途 |
| CN111925345B (zh) * | 2020-08-21 | 2023-09-29 | 上海科利生物医药有限公司 | 一种手性2-氨甲基四氢呋喃的制备方法 |
| AR123793A1 (es) | 2020-10-19 | 2023-01-11 | Bristol Myers Squibb Co | Compuestos de triazolopiridinilo como inhibidores de quinasas |
| CN116745361A (zh) * | 2021-02-10 | 2023-09-12 | 中央硝子株式会社 | 树脂组合物、树脂膜、基材、聚合物以及聚合性单体 |
| CN113563214B (zh) * | 2021-07-06 | 2024-02-02 | 山东鲁泰控股集团有限公司石墨烯高分子复合材料研发中心 | 一种氨基乙酸的合成方法 |
| CN113527220A (zh) * | 2021-07-26 | 2021-10-22 | 京博农化科技有限公司 | 一种脱硫丙硫菌唑异构体的合成方法 |
| CN114989079B (zh) * | 2022-06-21 | 2023-06-23 | 中国药科大学 | Ripk1激酶靶点抑制剂及其医药用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5116687B2 (ja) | 2005-11-02 | 2013-01-09 | バイエル・ファルマ・アクチェンゲゼルシャフト | がんおよび他の過剰増殖性疾患の処置のためのピロロ［２，１−ｆ］［１，２，４］トリアジン−４−イルアミンＩＧＦ−１Ｒキナーゼ阻害剤 |
| ES2365869T3 (es) * | 2005-11-17 | 2011-10-11 | OSI Pharmaceuticals, LLC | COMPUESTOS BICÍCLICOS FUSIONADOS INHIBIDORES DE LA mTOR. |
| PE20070855A1 (es) | 2005-12-02 | 2007-10-14 | Bayer Pharmaceuticals Corp | Derivados de 4-amino-pirrolotriazina sustituida como inhibidores de quinasas |
| WO2007064931A2 (en) | 2005-12-02 | 2007-06-07 | Bayer Healthcare Llc | Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis |
| GB2467670B (en) * | 2007-10-04 | 2012-08-01 | Intellikine Inc | Chemical entities and therapeutic uses thereof |
| US8765754B2 (en) | 2009-04-29 | 2014-07-01 | Locus Pharmaceuticals, Inc. | Pyrrolotriazine compounds |
| TW201107329A (en) * | 2009-07-30 | 2011-03-01 | Oncotherapy Science Inc | Fused imidazole derivative having ttk inhibitory action |
| IL266563B (en) | 2009-10-06 | 2022-09-01 | Millennium Pharm Inc | Heterocyclic compounds useful as pdk1 inhibitors |
| WO2011123493A1 (en) * | 2010-03-31 | 2011-10-06 | Bristol-Myers Squibb Company | Substituted pyrrolotriazines as protein kinase inhibitors |
| US9783573B2 (en) | 2012-09-18 | 2017-10-10 | Bristol-Myers Squibb Company | IAP antagonists |
| EP3054955B1 (en) | 2013-10-11 | 2018-05-30 | Bristol-Myers Squibb Company | Pyrrolotriazine kinase inhibitors |
| EP3209665B1 (en) | 2014-10-22 | 2019-08-14 | Bristol-Myers Squibb Company | Substituted pyrrolotriazine amine compounds as pi3k inhibitors |
| ES2807785T3 (es) | 2014-10-22 | 2021-02-24 | Bristol Myers Squibb Co | Compuestos de heteroarilamina bicíclicos como inhibidores de pi3k |
| KR102483020B1 (ko) | 2016-03-28 | 2023-01-04 | 인사이트 코포레이션 | Tam 저해제로서의 피롤로트리아진 화합물 |
| WO2018017435A1 (en) | 2016-07-22 | 2018-01-25 | Accro Bioscience Inc. | Heteroaryl compounds as inhibitors of necrosis, composition and application thereof |
| EP3580220B1 (en) | 2017-02-13 | 2021-11-17 | Bristol-Myers Squibb Company | Aminotriazolopyridines as kinase inhibitors |
| DK3704118T3 (da) | 2017-10-30 | 2022-03-14 | Bristol Myers Squibb Co | Aminoimidazopyrazin som kinasehæmmere |
| EP3849968B1 (en) | 2018-09-13 | 2022-12-21 | Bristol-Myers Squibb Company | 1h-indazole carboxamides as receptor-interacting protein kinase 1 inhibitors (ripk1) |
| EP3849969B1 (en) | 2018-09-13 | 2023-04-19 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
-
2019
- 2019-01-24 SG SG11202007035YA patent/SG11202007035YA/en unknown
- 2019-01-24 JP JP2020540798A patent/JP7307734B2/ja active Active
- 2019-01-24 CN CN201980019863.4A patent/CN112262139B/zh active Active
- 2019-01-24 EA EA202091777A patent/EA202091777A1/ru unknown
- 2019-01-24 US US16/963,886 patent/US11618753B2/en active Active
- 2019-01-24 BR BR112020014516-5A patent/BR112020014516A2/pt not_active Application Discontinuation
- 2019-01-24 CA CA3088548A patent/CA3088548A1/en active Pending
- 2019-01-24 AR ARP190100156A patent/AR114186A1/es unknown
- 2019-01-24 ES ES19704524T patent/ES2959399T3/es active Active
- 2019-01-24 WO PCT/US2019/014918 patent/WO2019147782A1/en not_active Ceased
- 2019-01-24 KR KR1020207024141A patent/KR102759231B1/ko active Active
- 2019-01-24 AU AU2019211382A patent/AU2019211382B2/en not_active Ceased
- 2019-01-24 EP EP19704524.8A patent/EP3743430B1/en active Active
- 2019-01-24 MX MX2020007531A patent/MX2020007531A/es unknown
- 2019-01-25 TW TW108102873A patent/TW201940485A/zh unknown
-
2020
- 2020-07-24 IL IL276269A patent/IL276269A/en unknown
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