JP2023546205A5 - - Google Patents
Info
- Publication number
- JP2023546205A5 JP2023546205A5 JP2023524121A JP2023524121A JP2023546205A5 JP 2023546205 A5 JP2023546205 A5 JP 2023546205A5 JP 2023524121 A JP2023524121 A JP 2023524121A JP 2023524121 A JP2023524121 A JP 2023524121A JP 2023546205 A5 JP2023546205 A5 JP 2023546205A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound according
- alkoxy
- hydroxy
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU102145 | 2020-10-21 | ||
| LULU102145 | 2020-10-21 | ||
| PCT/EP2021/079141 WO2022084417A1 (en) | 2020-10-21 | 2021-10-20 | Conjugated tlr7 and nod2 agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023546205A JP2023546205A (ja) | 2023-11-01 |
| JP2023546205A5 true JP2023546205A5 (https=) | 2024-09-06 |
Family
ID=74175904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023524121A Pending JP2023546205A (ja) | 2020-10-21 | 2021-10-20 | コンジュゲートｔｌｒ７およびｎｏｄ２アゴニスト |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230382886A1 (https=) |
| EP (1) | EP4232094A1 (https=) |
| JP (1) | JP2023546205A (https=) |
| CN (1) | CN116600830A (https=) |
| AU (1) | AU2021363606A1 (https=) |
| CA (1) | CA3196221A1 (https=) |
| WO (1) | WO2022084417A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024102639A1 (en) * | 2022-11-08 | 2024-05-16 | The Scripps Research Institute | N-arylpyrazole nod2 agonists as promoters of immune checkpoint inhibitor therapy |
| WO2025040743A1 (en) * | 2023-08-22 | 2025-02-27 | Univerza V Ljubljani | Conjugated tlr7 and rig-i agonists |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006242920A1 (en) | 2005-05-04 | 2006-11-09 | Pfizer Limited | 2-amido-6-amino-8-oxopurine derivatives as Toll-Like receptor modulators for the treatment of cancer and viral infections, such as hepatitis C |
| CN101304748A (zh) | 2005-08-22 | 2008-11-12 | 加利福尼亚大学董事会 | Tlr激动剂 |
| US8138172B2 (en) | 2006-07-05 | 2012-03-20 | Astrazeneca Ab | 8-oxoadenine derivatives acting as modulators of TLR7 |
| CN101790380B (zh) * | 2007-02-07 | 2013-07-10 | 加利福尼亚大学董事会 | 合成tlr激动剂的缀合物及其应用 |
| BRPI0917013A2 (pt) | 2008-08-11 | 2016-02-16 | Glaxosmithkline Llc | métodos para tratar doenças alérgicas e outras condições inflamatórias, e para tratar ou prevenir doença, composto, composição farmacêutica, e, uso de um composto |
| KR20110117705A (ko) | 2009-02-11 | 2011-10-27 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 톨-유사 수용체 조정제 및 질병의 치료 |
| AU2011247358B2 (en) | 2010-04-30 | 2014-10-30 | Urogen Pharma Ltd. | Phospholipid drug analogs |
| WO2012038058A1 (en) | 2010-09-21 | 2012-03-29 | Telormedix Sa | Treatment of conditions by toll-like receptor modulators |
| US10471139B2 (en) * | 2013-08-15 | 2019-11-12 | The University Of Kansas | Toll-like receptor agonists |
| AU2017318601B2 (en) * | 2016-09-02 | 2020-09-03 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
| US10472361B2 (en) | 2017-08-16 | 2019-11-12 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor |
| US10508115B2 (en) | 2017-08-16 | 2019-12-17 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor |
| US10457681B2 (en) | 2017-08-16 | 2019-10-29 | Bristol_Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor |
| WO2019197598A1 (en) | 2018-04-13 | 2019-10-17 | Glaxosmithkline Biologicals Sa | Tlr7 and / or tlr8 agonists |
| WO2019209811A1 (en) | 2018-04-24 | 2019-10-31 | Bristol-Myers Squibb Company | Macrocyclic toll-like receptor 7 (tlr7) agonists |
-
2021
- 2021-10-20 JP JP2023524121A patent/JP2023546205A/ja active Pending
- 2021-10-20 CA CA3196221A patent/CA3196221A1/en active Pending
- 2021-10-20 US US18/032,612 patent/US20230382886A1/en active Pending
- 2021-10-20 EP EP21791419.1A patent/EP4232094A1/en active Pending
- 2021-10-20 CN CN202180085916.XA patent/CN116600830A/zh active Pending
- 2021-10-20 AU AU2021363606A patent/AU2021363606A1/en active Pending
- 2021-10-20 WO PCT/EP2021/079141 patent/WO2022084417A1/en not_active Ceased
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