JP2023542924A5 - - Google Patents
Info
- Publication number
- JP2023542924A5 JP2023542924A5 JP2023518145A JP2023518145A JP2023542924A5 JP 2023542924 A5 JP2023542924 A5 JP 2023542924A5 JP 2023518145 A JP2023518145 A JP 2023518145A JP 2023518145 A JP2023518145 A JP 2023518145A JP 2023542924 A5 JP2023542924 A5 JP 2023542924A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- fusion protein
- carboxypeptidase
- cpb
- bioreactor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063081380P | 2020-09-22 | 2020-09-22 | |
| US63/081,380 | 2020-09-22 | ||
| US202163225832P | 2021-07-26 | 2021-07-26 | |
| US63/225,832 | 2021-07-26 | ||
| PCT/US2021/051185 WO2022066595A1 (en) | 2020-09-22 | 2021-09-21 | Methods for producing therapeutic proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023542924A JP2023542924A (ja) | 2023-10-12 |
| JP2023542924A5 true JP2023542924A5 (cg-RX-API-DMAC7.html) | 2024-10-01 |
| JP7808097B2 JP7808097B2 (ja) | 2026-01-28 |
Family
ID=78135186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023518145A Active JP7808097B2 (ja) | 2020-09-22 | 2021-09-21 | 治療タンパク質を生産するための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12486525B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP4217383A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7808097B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20230073270A (cg-RX-API-DMAC7.html) |
| CN (1) | CN116194570A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2022066595A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202548027A (zh) * | 2024-01-23 | 2025-12-16 | 美商安進公司 | 用於調節單株抗體電荷變體之方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4515893A (en) | 1979-04-26 | 1985-05-07 | Ortho Pharmaceutical Corporation | Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells |
| US5672347A (en) | 1984-07-05 | 1997-09-30 | Genentech, Inc. | Tumor necrosis factor antagonists and their use |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| US5091313A (en) | 1988-08-05 | 1992-02-25 | Tanox Biosystems, Inc. | Antigenic epitopes of IgE present on B cell but not basophil surface |
| US5720937A (en) | 1988-01-12 | 1998-02-24 | Genentech, Inc. | In vivo tumor detection assay |
| DE68919361T2 (de) | 1988-06-21 | 1995-05-24 | Genentech Inc | Therapeutische zusammensetzungen für die behandlung von myocard-infarkten. |
| US5126250A (en) | 1988-09-28 | 1992-06-30 | Eli Lilly And Company | Method for the reduction of heterogeneity of monoclonal antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ES2193136T3 (es) | 1991-08-14 | 2003-11-01 | Genentech Inc | Variantes de inmunoglubina para receptores especificos de fc epsilon. |
| AU687755B2 (en) | 1992-08-21 | 1998-03-05 | Genentech Inc. | Method for treating an LFA-1-mediated disorder |
| US5736137A (en) | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| ES2108566T3 (es) | 1993-12-10 | 1997-12-16 | Genentech Inc | Procedimientos para diagnosticar alergias y para seleccionar agentes terapeuticos antialergicos. |
| WO1995019181A1 (en) | 1994-01-18 | 1995-07-20 | Genentech, Inc. | A METHOD OF TREATMENT OF PARASITIC INFECTION USING IgE ANTAGONISTS |
| US5707622A (en) | 1994-03-03 | 1998-01-13 | Genentech, Inc. | Methods for treating ulcerative colitis |
| IL117645A (en) | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
| JPH11507535A (ja) | 1995-06-07 | 1999-07-06 | イムクローン システムズ インコーポレイテッド | 腫瘍の成長を抑制する抗体および抗体フラグメント類 |
| CA2242414C (en) | 1996-01-23 | 2012-01-03 | Genentech, Inc. | Anti-cd18 antibodies for use against stroke |
| US7147851B1 (en) | 1996-08-15 | 2006-12-12 | Millennium Pharmaceuticals, Inc. | Humanized immunoglobulin reactive with α4β7 integrin |
| EP0941344B1 (en) | 1996-11-27 | 2004-05-19 | Genentech, Inc. | HUMANIZED ANTI-CD11a ANTIBODIES |
| KR100816621B1 (ko) | 1997-04-07 | 2008-03-24 | 제넨테크, 인크. | 항-ｖｅｇｆ 항체 |
| ES2293682T5 (es) | 1997-05-15 | 2011-11-17 | Genentech, Inc. | Anticuerpo anti-apo2. |
| US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| ES2309012T3 (es) | 1999-10-29 | 2008-12-16 | Genentech, Inc. | Composiciones del anticuerpo anti-psca y a sus procedimientos contra celulas cancerigenas que expresen psca. |
| PT2837680T (pt) | 2011-07-01 | 2020-04-17 | Amgen Inc | Cultura celular de mamífero |
| SG11201401422VA (en) | 2011-10-27 | 2014-09-26 | Genmab As | Production of heterodimeric proteins |
| HUE035685T2 (en) | 2011-11-02 | 2018-05-28 | Hoffmann La Roche | Overload and elute chromatography |
| DK2970994T3 (da) | 2013-03-15 | 2019-10-28 | Lonza Ag | Konstitutiv promotor |
| US9813410B2 (en) | 2014-06-26 | 2017-11-07 | Rakuten, Inc. | Information processing apparatus, information processing method, and information processing program |
| EP3699269A1 (en) | 2015-09-22 | 2020-08-26 | F. Hoffmann-La Roche AG | Expression of fc-containing proteins |
| HRP20210830T1 (hr) | 2016-10-17 | 2021-08-20 | Enzene Biosciences Ltd. | Kontinuirani proces smanjenja heterogenosti terapijskog proteina |
-
2021
- 2021-09-21 EP EP21791166.8A patent/EP4217383A1/en active Pending
- 2021-09-21 WO PCT/US2021/051185 patent/WO2022066595A1/en not_active Ceased
- 2021-09-21 US US18/245,753 patent/US12486525B2/en active Active
- 2021-09-21 JP JP2023518145A patent/JP7808097B2/ja active Active
- 2021-09-21 CN CN202180064217.7A patent/CN116194570A/zh active Pending
- 2021-09-21 KR KR1020237013257A patent/KR20230073270A/ko active Pending
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