JP2023539695A5 - - Google Patents
Info
- Publication number
- JP2023539695A5 JP2023539695A5 JP2023537724A JP2023537724A JP2023539695A5 JP 2023539695 A5 JP2023539695 A5 JP 2023539695A5 JP 2023537724 A JP2023537724 A JP 2023537724A JP 2023537724 A JP2023537724 A JP 2023537724A JP 2023539695 A5 JP2023539695 A5 JP 2023539695A5
- Authority
- JP
- Japan
- Prior art keywords
- acrylamide
- indazole
- alkyl
- alkylene
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2013731.1 | 2020-09-01 | ||
| GBGB2013731.1A GB202013731D0 (en) | 2020-09-01 | 2020-09-01 | Novel cmpounds |
| PCT/GB2021/052262 WO2022049377A1 (en) | 2020-09-01 | 2021-09-01 | Novel compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023539695A JP2023539695A (ja) | 2023-09-15 |
| JP2023539695A5 true JP2023539695A5 (https=) | 2024-09-11 |
| JP7784431B2 JP7784431B2 (ja) | 2025-12-11 |
Family
ID=72749727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023537724A Active JP7784431B2 (ja) | 2020-09-01 | 2021-09-01 | 新規化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12497359B2 (https=) |
| EP (1) | EP4208448B1 (https=) |
| JP (1) | JP7784431B2 (https=) |
| CN (1) | CN116096712B (https=) |
| AU (1) | AU2021336750A1 (https=) |
| CA (1) | CA3190786A1 (https=) |
| GB (1) | GB202013731D0 (https=) |
| IL (1) | IL300904A (https=) |
| WO (1) | WO2022049377A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202013728D0 (en) * | 2020-09-01 | 2020-10-14 | Nrg Therapeutics Ltd | Novel compounds |
| GB202300833D0 (en) | 2023-01-19 | 2023-03-08 | Nrg Therapeutics Ltd | Novel compounds |
| CN121866248A (zh) | 2023-09-05 | 2026-04-14 | Nrg治疗有限公司 | 作为mptp抑制剂起作用的吡啶衍生物 |
| CN118255724A (zh) * | 2024-03-27 | 2024-06-28 | 河北天成药业股份有限公司 | 盐酸利多卡因杂质的合成方法及其反应检测方法 |
| GB202410534D0 (en) | 2024-07-18 | 2024-09-04 | Nrg Therapeutics Ltd | Novel method and uses |
| CN120025281A (zh) * | 2025-04-22 | 2025-05-23 | 九洲药业(杭州)有限公司 | 一种n,n-二异丁基-1h-吲唑-4-胺的中间体及制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1424078A4 (en) | 2001-09-04 | 2009-03-25 | Ono Pharmaceutical Co | RESPIRATORY DISEASE MEDICINES COMPRISING A SPHINGOSINE-1-PHOSPHATE RECEPTOR REGULATING AGENT |
| WO2003051876A1 (en) | 2001-12-14 | 2003-06-26 | Japan Tobacco Inc. | Pyrazolopyridine derivatives and medicinal use thereof |
| US7482488B2 (en) | 2002-08-29 | 2009-01-27 | Temple University - Of The Commonwealth System Of Higher Education | Aryl and heteroaryl propene amides, derivatives thereof and therapeutic uses thereof |
| EP1960355A1 (en) * | 2005-11-30 | 2008-08-27 | F.Hoffmann-La Roche Ag | 3-amino-1-arylpropyl indoles and aza-substituted indoles |
| US7915304B2 (en) | 2006-10-24 | 2011-03-29 | Congenia S.R.L. | Phenyl substituted maleimides as medicaments for blocking degenerative tissue damages by inhibiting MPT |
| EP2179984A1 (en) | 2008-10-27 | 2010-04-28 | Congenia S.r.l. | Acrylamido derivatives useful as inhibitors of the mitochondrial permeability transition |
| WO2011087051A1 (ja) | 2010-01-14 | 2011-07-21 | 国立大学法人金沢大学 | S1p2受容体アンタゴニストを含む粥状動脈硬化治療薬 |
| JP2017538676A (ja) | 2014-11-05 | 2017-12-28 | ザ ユニバーシティ オブ カンザス | ミトコンドリア透過性遷移孔（ｍｔＰＴＰ）の小分子阻害剤 |
| CA2884607A1 (en) | 2015-03-11 | 2016-09-11 | Stealth Peptides International, Inc. | Therapeutic compositions including acrylamido compounds or phenyl-substiituted maleimide compounds and uses thereof to treat and prevent mitochondrial diseases and conditions |
| WO2019002624A1 (de) | 2017-06-30 | 2019-01-03 | Kleuser, Burkhard | Mittel zur therapie entzündlicher darmerkrankungen |
| GB202013728D0 (en) | 2020-09-01 | 2020-10-14 | Nrg Therapeutics Ltd | Novel compounds |
-
2020
- 2020-09-01 GB GBGB2013731.1A patent/GB202013731D0/en not_active Ceased
-
2021
- 2021-09-01 IL IL300904A patent/IL300904A/en unknown
- 2021-09-01 AU AU2021336750A patent/AU2021336750A1/en not_active Abandoned
- 2021-09-01 CN CN202180053586.6A patent/CN116096712B/zh active Active
- 2021-09-01 WO PCT/GB2021/052262 patent/WO2022049377A1/en not_active Ceased
- 2021-09-01 EP EP21769790.3A patent/EP4208448B1/en active Active
- 2021-09-01 CA CA3190786A patent/CA3190786A1/en active Pending
- 2021-09-01 JP JP2023537724A patent/JP7784431B2/ja active Active
- 2021-09-01 US US18/023,488 patent/US12497359B2/en active Active
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