JP2023537274A5 - - Google Patents
Info
- Publication number
- JP2023537274A5 JP2023537274A5 JP2023504748A JP2023504748A JP2023537274A5 JP 2023537274 A5 JP2023537274 A5 JP 2023537274A5 JP 2023504748 A JP2023504748 A JP 2023504748A JP 2023504748 A JP2023504748 A JP 2023504748A JP 2023537274 A5 JP2023537274 A5 JP 2023537274A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- disease
- optionally substituted
- membered
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063062943P | 2020-08-07 | 2020-08-07 | |
| US63/062,943 | 2020-08-07 | ||
| US202063119915P | 2020-12-01 | 2020-12-01 | |
| US63/119,915 | 2020-12-01 | ||
| US202163186846P | 2021-05-11 | 2021-05-11 | |
| US63/186,846 | 2021-05-11 | ||
| PCT/US2021/044911 WO2022032073A2 (en) | 2020-08-07 | 2021-08-06 | Trpml modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023537274A JP2023537274A (ja) | 2023-08-31 |
| JP2023537274A5 true JP2023537274A5 (enExample) | 2024-07-31 |
Family
ID=80117687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023504748A Withdrawn JP2023537274A (ja) | 2020-08-07 | 2021-08-06 | Ｔｒｐｍｌモジュレーター |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230416262A1 (enExample) |
| EP (1) | EP4192957A4 (enExample) |
| JP (1) | JP2023537274A (enExample) |
| KR (1) | KR20230050369A (enExample) |
| CN (1) | CN116113698A (enExample) |
| TW (1) | TW202220958A (enExample) |
| WO (1) | WO2022032073A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL283639B2 (en) | 2018-12-20 | 2024-06-01 | Amgen Inc | Kif18a inhibitors |
| US12698266B2 (en) | 2019-12-19 | 2026-08-04 | Casma Therapeutics, Inc. | TRPML modulators |
| EP4284804A1 (en) | 2021-01-26 | 2023-12-06 | Schrödinger, Inc. | Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disorders |
| KR20240109977A (ko) | 2021-08-26 | 2024-07-12 | 볼라스트라 쎄라퓨틱스, 인코포레이티드 | Kif18a의 스피로 인돌린 억제제 |
| AU2023303023A1 (en) | 2022-07-07 | 2025-01-23 | Libra Therapeutics, Inc. | Oxazole trpml1 agonists and uses thereof |
| WO2024099404A1 (zh) * | 2022-11-10 | 2024-05-16 | 北京普祺医药科技股份有限公司 | 一种含氮螺环类化合物、药物组合物以及其用途 |
| WO2025151402A1 (en) * | 2024-01-08 | 2025-07-17 | Libra Therapeutics, Inc. | Thiazole trpml1 agonists and uses thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10229777A1 (de) * | 2002-07-03 | 2004-01-29 | Bayer Ag | Indolin-Phenylsulfonamid-Derivate |
| CA2529513A1 (en) * | 2003-06-17 | 2005-01-06 | Janssen Pharmaceutica N.V. | Process for the preparation of nonpeptide substituted spirobenzoazepine derivatives |
| AU2004299201B2 (en) * | 2003-12-09 | 2009-12-03 | F. Hoffmann-La Roche Ag | Benzoxazine derivatives and uses thereof |
| TW200522944A (en) * | 2003-12-23 | 2005-07-16 | Lilly Co Eli | CB1 modulator compounds |
| AU2004309419A1 (en) * | 2003-12-23 | 2005-07-14 | Arena Pharmaceuticals, Inc. | Novel spiroindoline or spiroisoquinoline compounds, methods of use and compositions thereof |
| DE102005020230A1 (de) * | 2005-04-30 | 2006-11-09 | Bayer Healthcare Ag | Verwendung von Indolin-Phenylsulfonamid-Derivaten |
| US20080200491A1 (en) * | 2005-06-22 | 2008-08-21 | Thuy-Anh Tran | 1,2-Dihydro-Spiro[3H-Indole-3,4'-Piperidine] Compounds, as Modulators of the Mas Receptor Novel |
| WO2007057775A1 (en) * | 2005-11-21 | 2007-05-24 | Pfizer Limited | Spiropiperidine derivatives |
| CA2634456A1 (en) * | 2005-12-22 | 2007-07-05 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| EP2076517A1 (en) * | 2006-09-22 | 2009-07-08 | Janssen Pharmaceutica N.V. | Spiro benzazepines as vasopressin antagonists |
| WO2008036755A1 (en) * | 2006-09-22 | 2008-03-27 | Janssen Pharmaceutica N.V. | Spiro benzazepines used as vasopressin antagonists |
| AR066834A1 (es) * | 2007-06-06 | 2009-09-16 | Janssen Pharmaceutica Nv | Espirobenzoazepanos como antagonistas de vasopresina, composiciones farmaceuticas que los contienen, proceso de preparacion y usos para el tratamiento de afecciones cardiacas, renales y del sistema nervioso central. |
| EP2224803B1 (en) * | 2007-11-21 | 2014-04-02 | Janssen Pharmaceutica N.V. | Spiropiperidines for use as tryptase inhibitors |
| WO2015091315A1 (en) * | 2013-12-19 | 2015-06-25 | Bayer Pharma Aktiengesellschaft | Spiro[indolin-3,4'-piperidine] derivatives as gnrh receptor antagonists |
| WO2016088903A1 (en) * | 2014-12-05 | 2016-06-09 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds |
| WO2018208630A1 (en) * | 2017-05-07 | 2018-11-15 | Calygene Biotechnology Inc. | Aryl-sulfonamide and aryl-sulfone derivatives as trpml modulators |
| CN112469758B (zh) * | 2018-07-26 | 2025-10-28 | 三菱瓦斯化学株式会社 | 固化性组合物、预浸料、树脂片、覆金属箔层叠板和印刷电路板 |
| CN109568321B (zh) * | 2019-01-14 | 2022-02-22 | 山东轩竹医药科技有限公司 | RORγ调节剂 |
| US12698266B2 (en) * | 2019-12-19 | 2026-08-04 | Casma Therapeutics, Inc. | TRPML modulators |
-
2021
- 2021-08-06 TW TW110129020A patent/TW202220958A/zh unknown
- 2021-08-06 EP EP21853420.4A patent/EP4192957A4/en not_active Withdrawn
- 2021-08-06 JP JP2023504748A patent/JP2023537274A/ja not_active Withdrawn
- 2021-08-06 WO PCT/US2021/044911 patent/WO2022032073A2/en not_active Ceased
- 2021-08-06 CN CN202180057615.6A patent/CN116113698A/zh active Pending
- 2021-08-06 KR KR1020237007509A patent/KR20230050369A/ko not_active Withdrawn
- 2021-08-06 US US18/019,638 patent/US20230416262A1/en not_active Abandoned
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