JP2023537271A5 - - Google Patents
Info
- Publication number
- JP2023537271A5 JP2023537271A5 JP2023504724A JP2023504724A JP2023537271A5 JP 2023537271 A5 JP2023537271 A5 JP 2023537271A5 JP 2023504724 A JP2023504724 A JP 2023504724A JP 2023504724 A JP2023504724 A JP 2023504724A JP 2023537271 A5 JP2023537271 A5 JP 2023537271A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- heterocycloalkyl
- heteroaryl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063056165P | 2020-07-24 | 2020-07-24 | |
| US63/056,165 | 2020-07-24 | ||
| US202063113555P | 2020-11-13 | 2020-11-13 | |
| US63/113,555 | 2020-11-13 | ||
| PCT/US2021/042960 WO2022020714A1 (en) | 2020-07-24 | 2021-07-23 | Thiophene hsd17b13 inhibitors and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023537271A JP2023537271A (ja) | 2023-08-31 |
| JP2023537271A5 true JP2023537271A5 (enExample) | 2024-07-18 |
Family
ID=79729016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023504724A Pending JP2023537271A (ja) | 2020-07-24 | 2021-07-23 | チオフェンｈｓｄ１７ｂ１３阻害剤とその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230278978A1 (enExample) |
| EP (1) | EP4185381A4 (enExample) |
| JP (1) | JP2023537271A (enExample) |
| CN (1) | CN116323578A (enExample) |
| TW (1) | TW202220967A (enExample) |
| WO (1) | WO2022020714A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4244210A4 (en) | 2020-11-13 | 2024-10-30 | Inipharm, Inc. | Dichlorophenol hsd17b13 inhibitors and uses thereof |
| US12617772B2 (en) | 2021-04-05 | 2026-05-05 | Inipharm, Inc. | Hydroxypyridine HSD17B13 inhibitors and uses thereof |
| JP2024534799A (ja) | 2021-08-20 | 2024-09-26 | エナンタ ファーマシューティカルズ インコーポレイテッド | １７－ベータ－ヒドロキシステロイドデヒドロゲナーゼ１３型阻害剤及びその使用方法 |
| KR20240122834A (ko) * | 2021-12-15 | 2024-08-13 | 브리스톨-마이어스 스큅 컴퍼니 | Rxfp1 효능제로서의 벤조티오펜 유도체 |
| AU2023213627A1 (en) * | 2022-01-26 | 2024-08-15 | Inipharm, Inc. | 2-substituted thiazole hsd17b13 inhibitors and uses thereof |
| EP4514782B1 (en) | 2022-05-19 | 2025-09-10 | Astrazeneca AB | Amido heteroaromatic compounds useful in the treatment of liver diseases |
| WO2023237504A1 (en) | 2022-06-09 | 2023-12-14 | Boehringer Ingelheim International Gmbh | Hsd17b13 inhibitors |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19642451A1 (de) * | 1996-10-15 | 1998-04-16 | Merck Patent Gmbh | Aminothiophencarbonsäureamide |
| WO2004085382A1 (ja) * | 2003-03-27 | 2004-10-07 | Kirin Beer Kabushiki Kaisha | 生体内リン輸送を阻害する化合物およびそれを含んでなる医薬 |
| CA2583259C (en) * | 2004-10-08 | 2011-08-02 | Astellas Pharma Inc. | Aromatic ring fused pyrimidine derivative |
| GB0513702D0 (en) * | 2005-07-04 | 2005-08-10 | Sterix Ltd | Compound |
| US7446195B2 (en) * | 2005-08-17 | 2008-11-04 | Schering Corporation | High affinity thiophene-based and furan-based kinase ligands |
| AU2011272782B2 (en) * | 2010-07-02 | 2014-11-27 | Gilead Sciences, Inc. | Apoptosis signal-regulating kinase inhibitors |
| JP2014514257A (ja) * | 2011-03-03 | 2014-06-19 | ユニバーシテーテ デス ザールランデス | 選択的１７ベータ−ヒドロキシステロイドデヒドロゲナーゼ２型阻害剤としてのビアリール誘導体 |
| ES2929283T3 (es) * | 2012-05-04 | 2022-11-28 | Us Health | Moduladores del receptor de relaxina 1 |
| CN105524053B (zh) * | 2014-10-19 | 2020-06-05 | 广东东阳光药业有限公司 | 四氢苯并噻吩化合物 |
| ES2969565T3 (es) * | 2015-09-30 | 2024-12-13 | Max Planck Ges Zur Foerderung Derwissenschaften E V | Derivados heteroarílicos como inhibidores de la sepiapterina reductasa |
| KR101870968B1 (ko) * | 2016-02-02 | 2018-06-25 | 부산대학교 산학협력단 | Ppar, fxr 및 ampk 활성화 효능을 갖는 신규 티오펜 화합물 또는 이의 약제학적으로 허용 가능한 염 및 이의 의학적 용도 |
| CA3033628C (en) * | 2016-08-15 | 2021-01-12 | Eli Lilly And Company | Condensed thiophene derivatives useful as napi-iib inhibitors |
| WO2018204775A1 (en) * | 2017-05-05 | 2018-11-08 | Hepanova, Inc. | Amino-aryl-benzamide compounds and methods of use thereof |
| IL275893B2 (en) * | 2018-02-08 | 2024-08-01 | Enyo Pharma | The history of unfused thiophene and their uses |
| CA3093547A1 (en) * | 2018-03-21 | 2019-09-26 | Ionis Pharmaceuticals, Inc. | Modulation of hsd17b13 expression |
-
2021
- 2021-07-23 WO PCT/US2021/042960 patent/WO2022020714A1/en not_active Ceased
- 2021-07-23 JP JP2023504724A patent/JP2023537271A/ja active Pending
- 2021-07-23 US US18/006,059 patent/US20230278978A1/en active Pending
- 2021-07-23 TW TW110127231A patent/TW202220967A/zh unknown
- 2021-07-23 CN CN202180065663.XA patent/CN116323578A/zh active Pending
- 2021-07-23 EP EP21846586.2A patent/EP4185381A4/en active Pending