JP2023536630A5 - - Google Patents

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Publication number
JP2023536630A5
JP2023536630A5 JP2023507633A JP2023507633A JP2023536630A5 JP 2023536630 A5 JP2023536630 A5 JP 2023536630A5 JP 2023507633 A JP2023507633 A JP 2023507633A JP 2023507633 A JP2023507633 A JP 2023507633A JP 2023536630 A5 JP2023536630 A5 JP 2023536630A5
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JP
Japan
Prior art keywords
amino acid
acid sequence
seq
antibody
chain variable
Prior art date
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Application number
JP2023507633A
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English (en)
Japanese (ja)
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JP7854423B2 (ja
JP2023536630A (ja
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Priority claimed from PCT/US2021/044330 external-priority patent/WO2022031695A1/en
Publication of JP2023536630A publication Critical patent/JP2023536630A/ja
Publication of JP2023536630A5 publication Critical patent/JP2023536630A5/ja
Application granted granted Critical
Publication of JP7854423B2 publication Critical patent/JP7854423B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2023507633A 2020-08-04 2021-08-03 Pd-l1結合性作用剤およびその使用 Active JP7854423B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063061109P 2020-08-04 2020-08-04
US63/061,109 2020-08-04
PCT/US2021/044330 WO2022031695A1 (en) 2020-08-04 2021-08-03 Pd-l1 binding agents and uses thereof

Publications (3)

Publication Number Publication Date
JP2023536630A JP2023536630A (ja) 2023-08-28
JP2023536630A5 true JP2023536630A5 (enExample) 2024-08-08
JP7854423B2 JP7854423B2 (ja) 2026-05-01

Family

ID=80118473

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023507633A Active JP7854423B2 (ja) 2020-08-04 2021-08-03 Pd-l1結合性作用剤およびその使用

Country Status (7)

Country Link
US (1) US12679893B2 (enExample)
EP (1) EP4192884A4 (enExample)
JP (1) JP7854423B2 (enExample)
CN (1) CN116390951A (enExample)
AU (1) AU2021322183A1 (enExample)
CA (1) CA3187850A1 (enExample)
WO (1) WO2022031695A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021322114A1 (en) * 2020-08-04 2023-03-02 Exelixis, Inc. Multispecific binding agents and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8362325B2 (en) 2007-10-03 2013-01-29 Ceres, Inc. Nucleotide sequences and corresponding polypeptides conferring modulated plant characteristics
MX2011000501A (es) * 2008-07-18 2011-05-23 Squibb Bristol Myers Co Composiciones monovalentes para union a cd28 y metodos de uso.
MX356367B (es) 2008-12-09 2018-05-25 Genentech Inc Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
MX2014001238A (es) * 2011-08-05 2014-09-22 Genentech Inc Anticuerpos contra poliubiquitina y métodos de uso.
MX2017001946A (es) * 2014-08-12 2017-06-19 Novartis Ag Conjugados de farmacos con anticuerpos anti-cdh6.
US11291721B2 (en) 2016-03-21 2022-04-05 Marengo Therapeutics, Inc. Multispecific and multifunctional molecules and uses thereof
JP7080213B2 (ja) * 2016-03-23 2022-06-03 スーチョウ トランセンタ セラピューティクス カンパニー,リミテッド 新規抗pd-l1抗体
US20190106494A1 (en) * 2016-06-13 2019-04-11 Askgene Pharma Inc. PD-L1 Specific Monoclonal Antibodies for Disease Treatment and Diagnosis
KR102379464B1 (ko) 2016-06-20 2022-03-29 키맵 리미티드 항-pd-l1 항체
JP7148414B2 (ja) 2016-06-29 2022-10-05 チェックポイント セラピューティクス,インコーポレイテッド Pd-l1特異的抗体およびそれを使用する方法
LT3592769T (lt) 2017-03-09 2024-08-26 Genmab A/S Antikūnai, atpažįstantys pd-l1
AU2018236272B2 (en) * 2017-03-15 2022-03-31 Silverback Therapeutics, Inc. Benzazepine compounds, conjugates, and uses thereof
EA201900443A1 (ru) 2017-04-18 2020-03-06 Р-Фарм Оверсиз Инк. Антитело к pd-l1 и его применение
EP3672634A1 (en) * 2017-08-24 2020-07-01 Invenra, Inc. Multivalent receptor-clustering agonist antibody constructs
EA039662B1 (ru) 2017-10-03 2022-02-24 Закрытое Акционерное Общество "Биокад" Антитела, специфичные к cd47 и pd-l1
WO2019084553A1 (en) 2017-10-27 2019-05-02 New York University ANTI-GALECTIN-9 ANTIBODIES AND USES THEREOF
US12110332B2 (en) 2017-11-20 2024-10-08 Taizhou Mabtech Pharmaceutical Co., Ltd. Bifunctional fusion protein targeting CD47 and PD-L1
CA3084626A1 (en) 2017-12-04 2019-06-13 Beijing Hanmi Pharmaceutical Co., Ltd. Anti-pd-l1/anti-cd47 bispecific antibody with structure like natural antibody and in form of heterodimer and preparation thereof
KR102845020B1 (ko) * 2017-12-28 2025-08-12 난징 레전드 바이오테크 씨오., 엘티디. Pd-l1에 대한 항체 및 변이체
WO2019179434A1 (en) 2018-03-20 2019-09-26 Wuxi Biologics (Shanghai) Co., Ltd. Novel bispecific pd-1/cd47 antibody molecules
CN112424225B (zh) 2018-03-29 2023-08-11 桂林三金药业股份有限公司 抗pd-l1抗体及其用途
GB2596411B (en) 2018-10-29 2023-09-20 Tigatx Inc Compositions and methods comprising IgA antibody constructs
CA3166328A1 (en) 2020-01-11 2021-07-15 Scholar Rock, Inc. Tgf-beta inhibitors and use thereof
AU2021322114A1 (en) 2020-08-04 2023-03-02 Exelixis, Inc. Multispecific binding agents and uses thereof
EP4475886A4 (en) 2022-02-09 2026-03-18 Exelixis Inc MULTI-SPECIFIC LIAISON AGENTS AND THEIR USES

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