JP2023535724A5 - - Google Patents
Info
- Publication number
- JP2023535724A5 JP2023535724A5 JP2023504527A JP2023504527A JP2023535724A5 JP 2023535724 A5 JP2023535724 A5 JP 2023535724A5 JP 2023504527 A JP2023504527 A JP 2023504527A JP 2023504527 A JP2023504527 A JP 2023504527A JP 2023535724 A5 JP2023535724 A5 JP 2023535724A5
- Authority
- JP
- Japan
- Prior art keywords
- crystalline polymorph
- cancer
- approximately
- pharmaceutical composition
- diffraction pattern
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063055754P | 2020-07-23 | 2020-07-23 | |
| US63/055,754 | 2020-07-23 | ||
| PCT/US2021/043021 WO2022020747A1 (en) | 2020-07-23 | 2021-07-23 | Polymorophs of 5-aza-4'-thio-2-deoxycytidine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023535724A JP2023535724A (ja) | 2023-08-21 |
| JP2023535724A5 true JP2023535724A5 (enExample) | 2024-07-31 |
| JP7679452B2 JP7679452B2 (ja) | 2025-05-19 |
Family
ID=79687860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023504527A Active JP7679452B2 (ja) | 2020-07-23 | 2021-07-23 | ５－アザ－４’－チオ－２’－デオキシシチジンの多形 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11447472B2 (enExample) |
| EP (1) | EP4185583A4 (enExample) |
| JP (1) | JP7679452B2 (enExample) |
| KR (1) | KR102866823B1 (enExample) |
| CN (1) | CN115989229A (enExample) |
| AU (1) | AU2021314329A1 (enExample) |
| BR (1) | BR112023001236A2 (enExample) |
| CA (1) | CA3186696A1 (enExample) |
| MX (1) | MX2023000979A (enExample) |
| WO (1) | WO2022020747A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230123277A1 (en) * | 2021-10-15 | 2023-04-20 | Akirabio, Inc. | Compositions comprising 2'-deoxycytidine analogs and use thereof for the treatment of sickle cell disease and thalassemia |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6020322A (en) | 1993-11-09 | 2000-02-01 | Pro-Neuron, Inc. | Acyl deoxyribonucleoside derivatives and uses thereof |
| US5591722A (en) * | 1989-09-15 | 1997-01-07 | Southern Research Institute | 2'-deoxy-4'-thioribonucleosides and their antiviral activity |
| US20060014949A1 (en) | 2004-07-13 | 2006-01-19 | Supergen Inc. | Compositions and formulations of decitabine polymorphs and methods of use thereof |
| CN103951583B (zh) | 2006-12-06 | 2016-01-06 | 科内图斯医药公司 | 一种抑制剂的结晶形式 |
| DK3782612T3 (da) | 2008-05-15 | 2024-01-15 | Celgene Corp | Orale formuleringer af cytidinanaloger og fremgangsmåder til anvendelse deraf |
| WO2011109012A1 (en) | 2010-03-02 | 2011-09-09 | Southern Research Institute | Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| US20110218170A1 (en) | 2010-03-02 | 2011-09-08 | Southern Research Institute | Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| CN106687139A (zh) | 2014-07-14 | 2017-05-17 | 吉利德科学公司 | 用于治疗癌症的组合 |
| US20160312261A1 (en) | 2015-04-24 | 2016-10-27 | Plasmia Biotech, S.L. | Enzymatic production of cytosinic nucleoside analogues |
| US20190240210A1 (en) | 2016-10-17 | 2019-08-08 | Daiichi Sankyo Company, Limited | Treatment Method by Combined Use of MDM2 Inhibitor and DNA Methyltransferase Inhibitor |
| JP7425734B2 (ja) * | 2018-02-01 | 2024-01-31 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ２’－デオキシヌクレオシドを製造するための立体選択的合成およびプロセス |
| US20210363170A1 (en) | 2018-04-19 | 2021-11-25 | Southern Research Institute | 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer |
-
2021
- 2021-07-23 BR BR112023001236A patent/BR112023001236A2/pt unknown
- 2021-07-23 MX MX2023000979A patent/MX2023000979A/es unknown
- 2021-07-23 CA CA3186696A patent/CA3186696A1/en active Pending
- 2021-07-23 CN CN202180052138.4A patent/CN115989229A/zh active Pending
- 2021-07-23 US US17/384,345 patent/US11447472B2/en active Active
- 2021-07-23 JP JP2023504527A patent/JP7679452B2/ja active Active
- 2021-07-23 AU AU2021314329A patent/AU2021314329A1/en active Pending
- 2021-07-23 KR KR1020237006092A patent/KR102866823B1/ko active Active
- 2021-07-23 EP EP21845710.9A patent/EP4185583A4/en active Pending
- 2021-07-23 WO PCT/US2021/043021 patent/WO2022020747A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023524912A5 (enExample) | ||
| US8927530B2 (en) | Therapeutic combination comprising a PLK1 inhibitor and an antineoplastic agent | |
| JP2021522197A5 (enExample) | ||
| AU2017382405A1 (en) | Compositions and methods for inhibiting arginase activity | |
| HRP20100563T1 (hr) | Derivati dihidropirazolopirimidinona | |
| JP2007534730A (ja) | 少なくとも一つのピロロベンゾジアゼピン誘導体とフルダラビンとを含有する治療用組成物 | |
| JP2010525057A5 (enExample) | ||
| CN102753176B (zh) | 含有cdc7抑制剂和抗癌药的治疗组合物 | |
| JP2020514344A5 (enExample) | ||
| JP2021528496A5 (enExample) | ||
| CN114469949A (zh) | 用于治疗弥漫大b细胞淋巴瘤的喹啉衍生物 | |
| US20100009906A1 (en) | Anticancer Treatments | |
| KR20210092204A (ko) | 비산트렌 제형의 제조 및 전달을 위한 방법 | |
| WO2005049031A1 (en) | Combination | |
| US20040006023A1 (en) | Antitumor theraphy comprising distamycin derivatives | |
| EA016873B1 (ru) | Применение для лечения лейкемии | |
| JP2024506847A5 (enExample) | ||
| CA3217787A1 (en) | Method for treating blood cancers | |
| KR102501514B1 (ko) | 2'-아미노-6-(2-아미노-6-(1-이소프로필피페리딘-4-일)-5-메틸피리미딘-4-일)-3'-플루오로-[2,4'-바이피리딘]-5-올 3염산염 및 이를 포함하는 약제학적 조성물 | |
| US12297175B2 (en) | Physics-driven discovery of novel small therapeutic compounds for use as a BCL-2 inhibitor | |
| US20230099876A1 (en) | Physics-driven discovery of novel small therapeutic compounds for use as a bcl-2 inhibitor | |
| US20230074698A1 (en) | Physics-driven discovery of novel small therapeutic compounds for use as a bcl-2 inhibitor | |
| CN102448454B (zh) | 包含plk1抑制剂和抗肿瘤剂的治疗性组合 | |
| US20230098888A1 (en) | Drg-mdm2-6 for use as a novel mouse double minute 2 (mdm2) inhibitor | |
| US20230071340A1 (en) | Drg-mdm2-4 for use as a novel mouse double minute 2 (mdm2) inhibitor |