JP2023524912A5 - - Google Patents
Info
- Publication number
- JP2023524912A5 JP2023524912A5 JP2023509462A JP2023509462A JP2023524912A5 JP 2023524912 A5 JP2023524912 A5 JP 2023524912A5 JP 2023509462 A JP2023509462 A JP 2023509462A JP 2023509462 A JP2023509462 A JP 2023509462A JP 2023524912 A5 JP2023524912 A5 JP 2023524912A5
- Authority
- JP
- Japan
- Prior art keywords
- approximately
- period
- pharmaceutical composition
- effective amount
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063014346P | 2020-04-23 | 2020-04-23 | |
| US63/014,346 | 2020-04-23 | ||
| PCT/US2021/028726 WO2021216936A1 (en) | 2020-04-23 | 2021-04-22 | Composition for treating blood cancer using 4'-thio-5-aza-2'-deoxycytidine and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023524912A JP2023524912A (ja) | 2023-06-13 |
| JP2023524912A5 true JP2023524912A5 (enExample) | 2024-05-01 |
Family
ID=78221459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023509462A Pending JP2023524912A (ja) | 2020-04-23 | 2021-04-22 | ４’－チオ－５－アザ－２’－デオキシシチジンを使用して血液がんを治療するための組成物及びその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12208112B2 (enExample) |
| EP (1) | EP4138843A4 (enExample) |
| JP (1) | JP2023524912A (enExample) |
| KR (1) | KR20230004768A (enExample) |
| CN (1) | CN115768432A (enExample) |
| AU (1) | AU2021260964A1 (enExample) |
| CA (1) | CA3176543A1 (enExample) |
| WO (1) | WO2021216936A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210363170A1 (en) * | 2018-04-19 | 2021-11-25 | Southern Research Institute | 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer |
| MX2024004801A (es) | 2021-10-19 | 2024-06-28 | Akirabio Inc | Composiciones que comprenden análogos de 2'- desoxicitidina, y uso de las mismas para el tratamiento de anemia de células falciformes, talasemia y cánceres. |
| KR20240139581A (ko) * | 2023-03-14 | 2024-09-23 | 주식회사 피노바이오 | 골수에 작용하는 5-아자-4'-티오-2'-데옥시사이티딘의 최고 혈중농도를 정교하게 제어가능한 경구용 제형 |
| CN117187391B (zh) * | 2023-09-15 | 2025-03-18 | 中国医学科学院北京协和医院 | 普卡霉素在垂体促肾上腺皮质激素腺瘤中的应用 |
| WO2025100762A1 (ko) * | 2023-11-08 | 2025-05-15 | 한국생명공학연구원 | 4'-티오-5-아자-2'-디옥시사이티딘을 포함하는 간질환의 개선, 예방 또는 치료용 조성물 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6020322A (en) | 1993-11-09 | 2000-02-01 | Pro-Neuron, Inc. | Acyl deoxyribonucleoside derivatives and uses thereof |
| US5591722A (en) | 1989-09-15 | 1997-01-07 | Southern Research Institute | 2'-deoxy-4'-thioribonucleosides and their antiviral activity |
| NZ509405A (en) | 1998-07-23 | 2004-10-29 | Southern Res Inst | Preparation of 1-(4-thio-thioarabinofuranosyl) cytosine derivatives and their use as anticancer agents and DNA replication inhibitors |
| US20060127990A1 (en) | 2002-08-22 | 2006-06-15 | Geneticlab Co., Ltd | 4'-thionucleotide |
| US20060014949A1 (en) | 2004-07-13 | 2006-01-19 | Supergen Inc. | Compositions and formulations of decitabine polymorphs and methods of use thereof |
| CN103951583B (zh) | 2006-12-06 | 2016-01-06 | 科内图斯医药公司 | 一种抑制剂的结晶形式 |
| DK3782612T3 (da) | 2008-05-15 | 2024-01-15 | Celgene Corp | Orale formuleringer af cytidinanaloger og fremgangsmåder til anvendelse deraf |
| US20110218170A1 (en) * | 2010-03-02 | 2011-09-08 | Southern Research Institute | Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| WO2011109383A1 (en) | 2010-03-02 | 2011-09-09 | Southern Research Institute | Use of 2'-deoxy -4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| WO2011109012A1 (en) | 2010-03-02 | 2011-09-09 | Southern Research Institute | Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| CN106687139A (zh) * | 2014-07-14 | 2017-05-17 | 吉利德科学公司 | 用于治疗癌症的组合 |
| TWI678373B (zh) | 2014-10-31 | 2019-12-01 | 日商富士軟片股份有限公司 | 硫代核苷衍生物或其鹽及醫藥組合物 |
| CN106661077B (zh) | 2015-04-03 | 2019-02-12 | 四川科伦博泰生物医药股份有限公司 | 4’-硫代核苷的新型化合物及其制备方法、药物组合物和应用 |
| US20160312261A1 (en) | 2015-04-24 | 2016-10-27 | Plasmia Biotech, S.L. | Enzymatic production of cytosinic nucleoside analogues |
| EP3303361A1 (en) | 2015-05-27 | 2018-04-11 | Idenix Pharmaceuticals LLC | Nucleotides for the treatment of cancer |
| EP3207932A1 (en) * | 2016-02-19 | 2017-08-23 | Universität Stuttgart | Dna methyltransferase inhibitors for rett syndrome therapy |
| US20190240210A1 (en) | 2016-10-17 | 2019-08-08 | Daiichi Sankyo Company, Limited | Treatment Method by Combined Use of MDM2 Inhibitor and DNA Methyltransferase Inhibitor |
| JP7425734B2 (ja) | 2018-02-01 | 2024-01-31 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ２’－デオキシヌクレオシドを製造するための立体選択的合成およびプロセス |
| US20210363170A1 (en) | 2018-04-19 | 2021-11-25 | Southern Research Institute | 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer |
| WO2020068657A1 (en) | 2018-09-25 | 2020-04-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | 2'-halogenated-4'-thio-2'-deoxy-5-azacytidine analogs and use thereof |
-
2021
- 2021-04-22 AU AU2021260964A patent/AU2021260964A1/en active Pending
- 2021-04-22 US US17/238,182 patent/US12208112B2/en active Active
- 2021-04-22 CN CN202180039610.0A patent/CN115768432A/zh active Pending
- 2021-04-22 WO PCT/US2021/028726 patent/WO2021216936A1/en not_active Ceased
- 2021-04-22 CA CA3176543A patent/CA3176543A1/en active Pending
- 2021-04-22 KR KR1020227040932A patent/KR20230004768A/ko active Pending
- 2021-04-22 EP EP21793672.3A patent/EP4138843A4/en active Pending
- 2021-04-22 JP JP2023509462A patent/JP2023524912A/ja active Pending
-
2024
- 2024-11-22 US US18/957,005 patent/US20250082662A1/en active Pending
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