JP2023524912A5 - - Google Patents
Info
- Publication number
- JP2023524912A5 JP2023524912A5 JP2023509462A JP2023509462A JP2023524912A5 JP 2023524912 A5 JP2023524912 A5 JP 2023524912A5 JP 2023509462 A JP2023509462 A JP 2023509462A JP 2023509462 A JP2023509462 A JP 2023509462A JP 2023524912 A5 JP2023524912 A5 JP 2023524912A5
- Authority
- JP
- Japan
- Prior art keywords
- approximately
- period
- pharmaceutical composition
- effective amount
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063014346P | 2020-04-23 | 2020-04-23 | |
| US63/014,346 | 2020-04-23 | ||
| PCT/US2021/028726 WO2021216936A1 (en) | 2020-04-23 | 2021-04-22 | Composition for treating blood cancer using 4'-thio-5-aza-2'-deoxycytidine and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023524912A JP2023524912A (ja) | 2023-06-13 |
| JP2023524912A5 true JP2023524912A5 (enExample) | 2024-05-01 |
Family
ID=78221459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023509462A Pending JP2023524912A (ja) | 2020-04-23 | 2021-04-22 | ４’－チオ－５－アザ－２’－デオキシシチジンを使用して血液がんを治療するための組成物及びその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12208112B2 (enExample) |
| EP (1) | EP4138843A4 (enExample) |
| JP (1) | JP2023524912A (enExample) |
| KR (1) | KR20230004768A (enExample) |
| CN (1) | CN115768432A (enExample) |
| AU (1) | AU2021260964A1 (enExample) |
| CA (1) | CA3176543A1 (enExample) |
| WO (1) | WO2021216936A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019204637A1 (en) * | 2018-04-19 | 2019-10-24 | Southern Research Institute | 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer |
| US11938143B2 (en) | 2021-10-19 | 2024-03-26 | Akirabio, Inc. | Compositions comprising 2′-deoxycytidine analogs and use thereof for the treatment of sickle cell disease, thalassemia, and cancers |
| KR20240139581A (ko) * | 2023-03-14 | 2024-09-23 | 주식회사 피노바이오 | 골수에 작용하는 5-아자-4'-티오-2'-데옥시사이티딘의 최고 혈중농도를 정교하게 제어가능한 경구용 제형 |
| CN117187391B (zh) * | 2023-09-15 | 2025-03-18 | 中国医学科学院北京协和医院 | 普卡霉素在垂体促肾上腺皮质激素腺瘤中的应用 |
| KR20250067704A (ko) * | 2023-11-08 | 2025-05-15 | 한국생명공학연구원 | 4'-티오-5-아자-2'-디옥시사이티딘을 포함하는 간질환의 개선, 예방 또는 치료용 조성물 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6020322A (en) | 1993-11-09 | 2000-02-01 | Pro-Neuron, Inc. | Acyl deoxyribonucleoside derivatives and uses thereof |
| US5591722A (en) | 1989-09-15 | 1997-01-07 | Southern Research Institute | 2'-deoxy-4'-thioribonucleosides and their antiviral activity |
| CA2338415C (en) | 1998-07-23 | 2006-10-10 | Southern Research Institute | Preparation of thioarabinofuranosyl compounds and use thereof |
| WO2004018494A1 (ja) | 2002-08-22 | 2004-03-04 | Geneticlab Co., Ltd. | ４’−チオヌクレオチド |
| US20060014949A1 (en) | 2004-07-13 | 2006-01-19 | Supergen Inc. | Compositions and formulations of decitabine polymorphs and methods of use thereof |
| CN103951583B (zh) | 2006-12-06 | 2016-01-06 | 科内图斯医药公司 | 一种抑制剂的结晶形式 |
| PL3692983T3 (pl) | 2008-05-15 | 2021-12-27 | Celgene Corporation | Doustne formulacje analogów cytydyny i sposoby ich zastosowania |
| WO2011109383A1 (en) * | 2010-03-02 | 2011-09-09 | Southern Research Institute | Use of 2'-deoxy -4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| US20110218170A1 (en) * | 2010-03-02 | 2011-09-08 | Southern Research Institute | Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| WO2011109012A1 (en) * | 2010-03-02 | 2011-09-09 | Southern Research Institute | Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents |
| SG11201610551TA (en) * | 2014-07-14 | 2017-01-27 | Gilead Sciences Inc | Combinations for treating cancers |
| TWI678373B (zh) | 2014-10-31 | 2019-12-01 | 日商富士軟片股份有限公司 | 硫代核苷衍生物或其鹽及醫藥組合物 |
| CN109553651B (zh) | 2015-04-03 | 2021-08-06 | 四川科伦博泰生物医药股份有限公司 | 4’-硫代核苷的新型化合物及其制备方法、药物组合物和应用 |
| US20160312261A1 (en) | 2015-04-24 | 2016-10-27 | Plasmia Biotech, S.L. | Enzymatic production of cytosinic nucleoside analogues |
| US10815264B2 (en) | 2015-05-27 | 2020-10-27 | Southern Research Institute | Nucleotides for the treatment of cancer |
| EP3207932A1 (en) * | 2016-02-19 | 2017-08-23 | Universität Stuttgart | Dna methyltransferase inhibitors for rett syndrome therapy |
| EP3527226A4 (en) * | 2016-10-17 | 2020-06-17 | Daiichi Sankyo Company, Limited | COMBINATION THERAPY PROCEDURE WITH MDM2 INHIBITOR AND DNA METHYL TRANSFERASE INHIBITOR |
| EP3746452B1 (en) * | 2018-02-01 | 2023-09-13 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Stereoselective synthesis and process for the manufacturing of 2'-deoxynucleosides |
| WO2019204637A1 (en) * | 2018-04-19 | 2019-10-24 | Southern Research Institute | 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer |
| EP3856754A1 (en) * | 2018-09-25 | 2021-08-04 | The United States of America, as represented by the Secretary, Department of Health and Human Services | 2'-halogenated-4'-thio-2'-deoxy-5-azacytidine analogs and use thereof |
-
2021
- 2021-04-22 EP EP21793672.3A patent/EP4138843A4/en active Pending
- 2021-04-22 US US17/238,182 patent/US12208112B2/en active Active
- 2021-04-22 JP JP2023509462A patent/JP2023524912A/ja active Pending
- 2021-04-22 CA CA3176543A patent/CA3176543A1/en active Pending
- 2021-04-22 WO PCT/US2021/028726 patent/WO2021216936A1/en not_active Ceased
- 2021-04-22 AU AU2021260964A patent/AU2021260964A1/en active Pending
- 2021-04-22 CN CN202180039610.0A patent/CN115768432A/zh active Pending
- 2021-04-22 KR KR1020227040932A patent/KR20230004768A/ko active Pending
-
2024
- 2024-11-22 US US18/957,005 patent/US20250082662A1/en active Pending
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