JP2023535121A5 - - Google Patents
Info
- Publication number
- JP2023535121A5 JP2023535121A5 JP2022570440A JP2022570440A JP2023535121A5 JP 2023535121 A5 JP2023535121 A5 JP 2023535121A5 JP 2022570440 A JP2022570440 A JP 2022570440A JP 2022570440 A JP2022570440 A JP 2022570440A JP 2023535121 A5 JP2023535121 A5 JP 2023535121A5
- Authority
- JP
- Japan
- Prior art keywords
- parkin
- seq
- optionally
- protein
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063027866P | 2020-05-20 | 2020-05-20 | |
| US202063027868P | 2020-05-20 | 2020-05-20 | |
| US63/027,868 | 2020-05-20 | ||
| US63/027,866 | 2020-05-20 | ||
| PCT/US2021/033491 WO2021236981A2 (en) | 2020-05-20 | 2021-05-20 | Engineered parkin and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023535121A JP2023535121A (ja) | 2023-08-16 |
| JP2023535121A5 true JP2023535121A5 (enExample) | 2024-05-29 |
| JP7872737B2 JP7872737B2 (ja) | 2026-06-10 |
Family
ID=78707577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022570440A Active JP7872737B2 (ja) | 2020-05-20 | 2021-05-20 | 操作されたパーキン及びその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230174994A1 (enExample) |
| EP (1) | EP4153614A4 (enExample) |
| JP (1) | JP7872737B2 (enExample) |
| CA (1) | CA3177341A1 (enExample) |
| WO (1) | WO2021236981A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102673203B1 (ko) | 2016-04-20 | 2024-06-10 | 센트로 데 인베스띠가씨오네스 에너제티까스 메디오암비엔딸레스 와이 테크놀로지까스, 오.에이., 엠.피. | Pklr의 유전자 발현 증강을 위한 조성물 및 방법 |
| AU2018352583B2 (en) | 2017-10-16 | 2025-04-17 | Centro de Investigaciones Energeticas, Medioambientales Y Tecnologicas, O.A., M.P. | Lentiviral vectors for delivery of PKLR to treat Pyruvate Kinase Deficiency |
| US12539316B2 (en) | 2018-04-11 | 2026-02-03 | Spacecraft Seven, Llc | Compositions and methods for stem cell transplant |
| IL278213B2 (en) | 2018-04-27 | 2026-04-01 | Rocket Pharmaceuticals Ltd | A gene therapy vector encoding an e3 ubiquitin protein ligase (park2) and use thereof in treating or inhibiting the onset of parkinson’s disease (pd) |
| IL280465B2 (en) | 2018-07-30 | 2025-03-01 | Centro De Investig Energeticas Medioambientales Y Tecnologicas O A M P | Methods for gene modification of hematopoietic cells |
| WO2022032226A1 (en) | 2020-08-07 | 2022-02-10 | Spacecraft Seven, Llc | Plakophilin-2 (pkp2) gene therapy using aav vector |
| CN119193701B (zh) * | 2024-09-13 | 2025-07-15 | 暨南大学 | 帕金森动物模型的构建方法与特异性靶向Parkin基因的gRNA及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009026116A2 (en) * | 2007-08-16 | 2009-02-26 | Genizon Biosciences, Inc. | Genemap of the human genes associated with longevity |
| WO2011053825A2 (en) * | 2009-10-30 | 2011-05-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions and methods for the treatment or prevention of mitochondrial diseases |
| WO2012050402A2 (ko) * | 2010-10-14 | 2012-04-19 | 주식회사 프로셀제약 | 세포투과성 parkin 재조합 단백질 및 이를 함유하는 퇴행성 뇌질환 치료용 약학적 조성물 |
| US9283287B2 (en) * | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| CA2898326C (en) * | 2013-01-18 | 2022-05-17 | Foundation Medicine, Inc. | Methods of treating cholangiocarcinoma |
| IL278213B2 (en) * | 2018-04-27 | 2026-04-01 | Rocket Pharmaceuticals Ltd | A gene therapy vector encoding an e3 ubiquitin protein ligase (park2) and use thereof in treating or inhibiting the onset of parkinson’s disease (pd) |
-
2021
- 2021-05-20 CA CA3177341A patent/CA3177341A1/en active Pending
- 2021-05-20 WO PCT/US2021/033491 patent/WO2021236981A2/en not_active Ceased
- 2021-05-20 JP JP2022570440A patent/JP7872737B2/ja active Active
- 2021-05-20 US US17/926,024 patent/US20230174994A1/en active Pending
- 2021-05-20 EP EP21807784.0A patent/EP4153614A4/en active Pending
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