JP2023534043A5 - - Google Patents

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Publication number
JP2023534043A5
JP2023534043A5 JP2023502945A JP2023502945A JP2023534043A5 JP 2023534043 A5 JP2023534043 A5 JP 2023534043A5 JP 2023502945 A JP2023502945 A JP 2023502945A JP 2023502945 A JP2023502945 A JP 2023502945A JP 2023534043 A5 JP2023534043 A5 JP 2023534043A5
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JP
Japan
Application number
JP2023502945A
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Japanese (ja)
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JP2023534043A (ja
JPWO2022016089A5 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/042033 external-priority patent/WO2022016089A2/en
Publication of JP2023534043A publication Critical patent/JP2023534043A/ja
Publication of JP2023534043A5 publication Critical patent/JP2023534043A5/ja
Publication of JPWO2022016089A5 publication Critical patent/JPWO2022016089A5/ja
Pending legal-status Critical Current

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JP2023502945A 2020-07-17 2021-07-16 ポリヌクレオチドを縮小サイズの脂質ナノ粒子に封入する方法及びその新規製剤 Pending JP2023534043A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063053274P 2020-07-17 2020-07-17
US63/053,274 2020-07-17
US202163194620P 2021-05-28 2021-05-28
US63/194,620 2021-05-28
PCT/US2021/042033 WO2022016089A2 (en) 2020-07-17 2021-07-16 Methods for encapsulating polynucleotides into reduced sizes of lipid nanoparticles and novel formulation thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2026017935A Division JP2026074198A (ja) 2020-07-17 2026-02-05 ポリヌクレオチドを縮小サイズの脂質ナノ粒子に封入する方法及びその新規製剤

Publications (3)

Publication Number Publication Date
JP2023534043A JP2023534043A (ja) 2023-08-07
JP2023534043A5 true JP2023534043A5 (https=) 2024-07-24
JPWO2022016089A5 JPWO2022016089A5 (https=) 2024-07-24

Family

ID=79555025

Family Applications (1)

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JP2023502945A Pending JP2023534043A (ja) 2020-07-17 2021-07-16 ポリヌクレオチドを縮小サイズの脂質ナノ粒子に封入する方法及びその新規製剤

Country Status (10)

Country Link
US (1) US20230320993A1 (https=)
EP (1) EP4181948A4 (https=)
JP (1) JP2023534043A (https=)
KR (1) KR20230052895A (https=)
CN (1) CN116437964A (https=)
AU (1) AU2021307952A1 (https=)
CA (1) CA3186033A1 (https=)
IL (1) IL299896A (https=)
MX (1) MX2023000806A (https=)
WO (1) WO2022016089A2 (https=)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
EP3515928B1 (en) 2016-09-23 2026-01-28 Duke University Unstructured non-repetitive polypeptides having lcst behavior
WO2019006374A1 (en) 2017-06-30 2019-01-03 Duke University ORDER AND DISORDER AS A DESIGN PRINCIPLE FOR STIMULI-SENSITIVE BIOPOLYMER NETWORKS
US12296018B2 (en) 2018-01-26 2025-05-13 Duke University Albumin binding peptide-drug (AlBiPeD) conjugates and methods of making and using same
EP3788343B1 (en) 2018-04-30 2024-03-27 Duke University Stimuli-responsive peg-like polymer-based drug delivery platform
WO2020051541A1 (en) 2018-09-07 2020-03-12 Duke University Nanoparticulate drug delivery systems
CN113166783B (zh) 2018-10-09 2024-10-11 不列颠哥伦比亚大学 包含无有机溶剂和去污剂的转染活性囊泡的组合物和系统以及与之相关的方法
US11512314B2 (en) 2019-07-12 2022-11-29 Duke University Amphiphilic polynucleotides
IL296763B2 (en) 2020-03-27 2026-04-01 Generation Bio Co New lipids and their nanoparticle compositions
KR20230172570A (ko) 2021-04-20 2023-12-22 제너레이션 바이오 컴퍼니 양이온성 지질 및 이의 조성물
US12508225B2 (en) 2021-05-28 2025-12-30 Beijing Tricisionbio Therapeutics Inc. Lipid compound and use thereof in delivery of nucleic acid
WO2022266032A1 (en) * 2021-06-14 2022-12-22 Generation Bio Co. Cationic lipids and compositions thereof
US20250281596A1 (en) * 2021-09-28 2025-09-11 Seqirus Inc. Ionizable cationic compound
CN118201605A (zh) * 2021-10-25 2024-06-14 杜克大学 基于poegma的脂质纳米粒子
WO2023190166A1 (ja) * 2022-03-28 2023-10-05 日油株式会社 ジスルフィド結合を有するカチオン性脂質、これを含む脂質膜構造体、これらのいずれかを含む核酸導入剤及び医薬品組成物、核酸を細胞又は標的細胞内へ導入する方法、及び細胞医薬品の製造方法
CN114685784B (zh) * 2022-04-26 2023-09-15 北京清科胜因生物科技有限公司 一种用于核酸递送的聚(2-噁唑啉)脂质与脂质纳米颗粒及应用
EP4536197A1 (en) * 2022-06-07 2025-04-16 Generation Bio Co. Lipid nanoparticle compositions and uses thereof
CN115105584B (zh) * 2022-06-28 2023-03-31 长春生物制品研究所有限责任公司 一种卡式瓶多剂量笔式注射组合包装的干扰素注射液
WO2024037577A1 (en) * 2022-08-18 2024-02-22 Suzhou Abogen Biosciences Co., Ltd. Composition of lipid nanoparticles
EP4594299A1 (en) * 2022-09-27 2025-08-06 Reinvigoron TheraTech, Inc. Compounds with cleavable disulfide moieties
CN120091992A (zh) * 2022-11-08 2025-06-03 三养控股公司 阳离子脂质及其制备方法
WO2024119103A1 (en) 2022-12-01 2024-06-06 Generation Bio Co. Lipid nanoparticles comprising nucleic acids and lipid-anchored polymers
EP4704855A1 (en) * 2023-04-26 2026-03-11 Saliogen Therapeutics, Inc. Lipid nanoparticle (lnp) formulations
US12311033B2 (en) 2023-05-31 2025-05-27 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
WO2025043146A2 (en) * 2023-08-24 2025-02-27 Molecular Axiom Inc. Lipid nanoparticle compositions and methods of using same
WO2025064850A1 (en) 2023-09-22 2025-03-27 BioNTech SE Rna constructs with n-terminal degrons to enhance an immune response
WO2025106754A1 (en) 2023-11-15 2025-05-22 BioNTech SE Coronavirus vaccine
GB202416789D0 (en) 2023-11-15 2025-01-01 BioNTech SE SARS-COV-2 immunogenic compositions
WO2025149492A1 (en) 2024-01-08 2025-07-17 BioNTech SE Rna encoding an immune inhibitory il-1 family member
WO2025166238A1 (en) * 2024-01-31 2025-08-07 Orna Therapeutics, Inc. Fast-shedding polyethylene glycol lipids
WO2025178465A1 (ko) * 2024-02-19 2025-08-28 주식회사 메디치바이오 신규한 이온화 지질 및 이를 이용한 지질 나노입자 조성물
WO2025230906A1 (en) * 2024-04-29 2025-11-06 Saliogen Therapeutics, Inc. Lipid nanoparticle (lnp) formulations
WO2025237830A1 (en) * 2024-05-15 2025-11-20 Evonik Operations Gmbh Polyoxyalkylene-1,2-di(alkyloxy)propanoxy-carbonylaminopropyl compounds, wherein the polyoxyalkylene is a poly(ethylene oxide) having c1 to c3-alkyloxymethyl side chains
WO2025255027A1 (en) * 2024-06-03 2025-12-11 Flagship Labs 114, Inc. Lipid nanoparticles for topical delivery
WO2026047603A1 (en) 2024-08-28 2026-03-05 BioNTech SE Sars-cov-2 immunogenic compositions
WO2026057625A1 (en) 2024-09-11 2026-03-19 BioNTech SE Peptidoglycan hydrolases having a chap domain with engineered active site
WO2026057626A1 (en) 2024-09-11 2026-03-19 BioNTech SE Peptidoglycan hydrolases having multiple enzymatically active domains
WO2026068864A1 (en) 2024-09-30 2026-04-02 BioNTech SE Engineered ch1 and cl domains for the prevention of chain mispairing
CN121421963A (zh) * 2026-01-04 2026-01-30 广州隽沐生物科技股份有限公司 一种用于难溶性活性经皮黏膜给药的装配材料及制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100015218A1 (en) * 2007-02-16 2010-01-21 Vasant Jadhav Compositions and methods for potentiated activity of biologically active molecules
JP6093710B2 (ja) * 2011-11-18 2017-03-08 日油株式会社 細胞内動態を改善したカチオン性脂質
HK1206644A1 (en) * 2012-03-29 2016-01-15 Shire Human Genetic Therapies, Inc. Lipid-derived neutral nanoparticles
EP4286012A3 (en) * 2015-09-17 2024-05-29 ModernaTX, Inc. Compounds and compositions for intracellular delivery of therapeutic agents
US11395798B2 (en) * 2015-10-08 2022-07-26 Nof Corporation O/W type emulsion
WO2017189870A1 (en) * 2016-04-27 2017-11-02 Massachusetts Institute Of Technology Stable nanoscale nucleic acid assemblies and methods thereof
US11583504B2 (en) * 2016-11-08 2023-02-21 Modernatx, Inc. Stabilized formulations of lipid nanoparticles
AU2018330208B2 (en) * 2017-09-08 2025-04-17 Generation Bio Co. Lipid nanoparticle formulations of non-viral, capsid-free DNA vectors
WO2019188867A1 (ja) * 2018-03-27 2019-10-03 日油株式会社 細胞内動態を改善した新規カチオン性脂質
JP7700101B2 (ja) * 2019-09-06 2025-06-30 ジェネレーション バイオ カンパニー 閉端dnaおよび切断可能脂質を含む脂質ナノ粒子組成物ならびにそれらの使用方法
AU2020385378A1 (en) * 2019-11-22 2022-04-07 Generation Bio Co. Ionizable lipids and nanoparticle compositions thereof
IL296763B2 (en) * 2020-03-27 2026-04-01 Generation Bio Co New lipids and their nanoparticle compositions
US20230181764A1 (en) * 2020-05-18 2023-06-15 Generation Bio Co. Novel lipids and nanoparticle compositions thereof

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