JP2023534043A5 - - Google Patents
Info
- Publication number
- JP2023534043A5 JP2023534043A5 JP2023502945A JP2023502945A JP2023534043A5 JP 2023534043 A5 JP2023534043 A5 JP 2023534043A5 JP 2023502945 A JP2023502945 A JP 2023502945A JP 2023502945 A JP2023502945 A JP 2023502945A JP 2023534043 A5 JP2023534043 A5 JP 2023534043A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- lipid
- item
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063053274P | 2020-07-17 | 2020-07-17 | |
| US63/053,274 | 2020-07-17 | ||
| US202163194620P | 2021-05-28 | 2021-05-28 | |
| US63/194,620 | 2021-05-28 | ||
| PCT/US2021/042033 WO2022016089A2 (en) | 2020-07-17 | 2021-07-16 | Methods for encapsulating polynucleotides into reduced sizes of lipid nanoparticles and novel formulation thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2026017935A Division JP2026074198A (ja) | 2020-07-17 | 2026-02-05 | ポリヌクレオチドを縮小サイズの脂質ナノ粒子に封入する方法及びその新規製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023534043A JP2023534043A (ja) | 2023-08-07 |
| JP2023534043A5 true JP2023534043A5 (https=) | 2024-07-24 |
Family
ID=79555025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023502945A Pending JP2023534043A (ja) | 2020-07-17 | 2021-07-16 | ポリヌクレオチドを縮小サイズの脂質ナノ粒子に封入する方法及びその新規製剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230320993A1 (https=) |
| EP (1) | EP4181948A4 (https=) |
| JP (1) | JP2023534043A (https=) |
| KR (1) | KR20230052895A (https=) |
| CN (1) | CN116437964A (https=) |
| AU (1) | AU2021307952A1 (https=) |
| CA (1) | CA3186033A1 (https=) |
| IL (1) | IL299896A (https=) |
| MX (1) | MX2023000806A (https=) |
| WO (1) | WO2022016089A2 (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11752213B2 (en) | 2015-12-21 | 2023-09-12 | Duke University | Surfaces having reduced non-specific binding and antigenicity |
| JP2020500150A (ja) | 2016-09-23 | 2020-01-09 | デューク ユニバーシティ | 下限臨界溶液温度挙動を有する非反復かつ非構造的ポリペプチド |
| WO2019006374A1 (en) | 2017-06-30 | 2019-01-03 | Duke University | ORDER AND DISORDER AS A DESIGN PRINCIPLE FOR STIMULI-SENSITIVE BIOPOLYMER NETWORKS |
| WO2019147954A1 (en) | 2018-01-26 | 2019-08-01 | Duke University | Albumin binding peptide-drug (aibiped) conjugates and methods of making and using same |
| EP3788343B1 (en) | 2018-04-30 | 2024-03-27 | Duke University | Stimuli-responsive peg-like polymer-based drug delivery platform |
| US12594347B2 (en) | 2018-09-07 | 2026-04-07 | Duke University | Nanoparticulate drug delivery systems |
| HRP20240586T1 (hr) | 2018-10-09 | 2024-07-19 | The University Of British Columbia | Sastavi i sustavi koji sadrže transfekcijske sposobne vezikle bez organskih otapala i deterdženta i s njim povezanim postupcima |
| US11512314B2 (en) | 2019-07-12 | 2022-11-29 | Duke University | Amphiphilic polynucleotides |
| JP7746280B2 (ja) | 2020-03-27 | 2025-09-30 | ジェネレーション バイオ カンパニー | 新規脂質及びそれらのナノ粒子組成物 |
| BR112023021504A2 (pt) * | 2021-04-20 | 2023-12-19 | Generation Bio Co | Lipídios catiônicos e composições dos mesmos |
| EP4310071A4 (en) * | 2021-05-28 | 2024-11-20 | Beijing Tricisionbio Therapeutics Inc. | LIPID COMPOUND AND USE THEREOF IN THE ADMINISTRATION OF NUCLEIC ACID |
| AU2022291742A1 (en) * | 2021-06-14 | 2023-12-21 | Generation Bio Co. | Cationic lipids and compositions thereof |
| US20250281596A1 (en) * | 2021-09-28 | 2025-09-11 | Seqirus Inc. | Ionizable cationic compound |
| CN118201605A (zh) * | 2021-10-25 | 2024-06-14 | 杜克大学 | 基于poegma的脂质纳米粒子 |
| WO2023190166A1 (ja) * | 2022-03-28 | 2023-10-05 | 日油株式会社 | ジスルフィド結合を有するカチオン性脂質、これを含む脂質膜構造体、これらのいずれかを含む核酸導入剤及び医薬品組成物、核酸を細胞又は標的細胞内へ導入する方法、及び細胞医薬品の製造方法 |
| CN114685784B (zh) * | 2022-04-26 | 2023-09-15 | 北京清科胜因生物科技有限公司 | 一种用于核酸递送的聚(2-噁唑啉)脂质与脂质纳米颗粒及应用 |
| EP4536197A1 (en) * | 2022-06-07 | 2025-04-16 | Generation Bio Co. | Lipid nanoparticle compositions and uses thereof |
| CN115105584B (zh) * | 2022-06-28 | 2023-03-31 | 长春生物制品研究所有限责任公司 | 一种卡式瓶多剂量笔式注射组合包装的干扰素注射液 |
| WO2024037577A1 (en) * | 2022-08-18 | 2024-02-22 | Suzhou Abogen Biosciences Co., Ltd. | Composition of lipid nanoparticles |
| US20240150306A1 (en) * | 2022-09-27 | 2024-05-09 | Reinvigoron Theratech, Inc. | Compounds with cleavable disulfide moieties |
| CN120091992A (zh) * | 2022-11-08 | 2025-06-03 | 三养控股公司 | 阳离子脂质及其制备方法 |
| WO2024119103A1 (en) | 2022-12-01 | 2024-06-06 | Generation Bio Co. | Lipid nanoparticles comprising nucleic acids and lipid-anchored polymers |
| WO2024226779A1 (en) * | 2023-04-26 | 2024-10-31 | Saliogen Therapeutics, Inc. | Lipid nanoparticle (lnp) formulations |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025043146A2 (en) * | 2023-08-24 | 2025-02-27 | Molecular Axiom Inc. | Lipid nanoparticle compositions and methods of using same |
| WO2025064850A1 (en) | 2023-09-22 | 2025-03-27 | BioNTech SE | Rna constructs with n-terminal degrons to enhance an immune response |
| FR3155424A1 (fr) | 2023-11-15 | 2025-05-23 | BioNTech SE | Compositions immunogènes contre le sars-cov-2 |
| WO2025106754A1 (en) | 2023-11-15 | 2025-05-22 | BioNTech SE | Coronavirus vaccine |
| WO2025149492A1 (en) | 2024-01-08 | 2025-07-17 | BioNTech SE | Rna encoding an immune inhibitory il-1 family member |
| WO2025166238A1 (en) * | 2024-01-31 | 2025-08-07 | Orna Therapeutics, Inc. | Fast-shedding polyethylene glycol lipids |
| WO2025178465A1 (ko) * | 2024-02-19 | 2025-08-28 | 주식회사 메디치바이오 | 신규한 이온화 지질 및 이를 이용한 지질 나노입자 조성물 |
| WO2025230906A1 (en) * | 2024-04-29 | 2025-11-06 | Saliogen Therapeutics, Inc. | Lipid nanoparticle (lnp) formulations |
| WO2025237830A1 (en) * | 2024-05-15 | 2025-11-20 | Evonik Operations Gmbh | Polyoxyalkylene-1,2-di(alkyloxy)propanoxy-carbonylaminopropyl compounds, wherein the polyoxyalkylene is a poly(ethylene oxide) having c1 to c3-alkyloxymethyl side chains |
| WO2025255027A1 (en) * | 2024-06-03 | 2025-12-11 | Flagship Labs 114, Inc. | Lipid nanoparticles for topical delivery |
| WO2026047603A1 (en) | 2024-08-28 | 2026-03-05 | BioNTech SE | Sars-cov-2 immunogenic compositions |
| WO2026057625A1 (en) | 2024-09-11 | 2026-03-19 | BioNTech SE | Peptidoglycan hydrolases having a chap domain with engineered active site |
| WO2026057626A1 (en) | 2024-09-11 | 2026-03-19 | BioNTech SE | Peptidoglycan hydrolases having multiple enzymatically active domains |
| WO2026068864A1 (en) | 2024-09-30 | 2026-04-02 | BioNTech SE | Engineered ch1 and cl domains for the prevention of chain mispairing |
| WO2026082899A2 (en) | 2024-10-16 | 2026-04-23 | BioNTech SE | Rna for preventing or treating tuberculosis |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2689042A1 (en) * | 2007-02-16 | 2008-08-28 | Merck & Co., Inc. | Compositions and methods for potentiated activity of biologicaly active molecules |
| WO2013073480A1 (ja) * | 2011-11-18 | 2013-05-23 | 日油株式会社 | 細胞内動態を改善したカチオン性脂質 |
| AU2013237874B2 (en) * | 2012-03-29 | 2018-01-18 | Translate Bio, Inc. | Lipid-derived neutral nanoparticles |
| JP6948313B6 (ja) * | 2015-09-17 | 2022-01-14 | モデルナティエックス インコーポレイテッド | 治療剤の細胞内送達のための化合物および組成物 |
| JP6875685B2 (ja) * | 2015-10-08 | 2021-05-26 | 日油株式会社 | Ｏ／ｗ型エマルション |
| WO2017189870A1 (en) * | 2016-04-27 | 2017-11-02 | Massachusetts Institute Of Technology | Stable nanoscale nucleic acid assemblies and methods thereof |
| US11583504B2 (en) * | 2016-11-08 | 2023-02-21 | Modernatx, Inc. | Stabilized formulations of lipid nanoparticles |
| KR102696307B1 (ko) * | 2017-09-08 | 2024-08-16 | 제너레이션 바이오 컴퍼니 | 비-바이러스성 캡시드-비함유 dna 벡터의 지질 나노입자 제형 |
| CN111902397B (zh) * | 2018-03-27 | 2024-04-12 | 日油株式会社 | 改进了细胞内动力学的阳离子脂质 |
| WO2021046265A1 (en) * | 2019-09-06 | 2021-03-11 | Generation Bio Co. | Lipid nanoparticle compositions comprising closed-ended dna and cleavable lipids and methods of use thereof |
| JP2023502576A (ja) * | 2019-11-22 | 2023-01-25 | ジェネレーション バイオ カンパニー | イオン化可能な脂質およびそれらのナノ粒子組成物 |
| JP7746280B2 (ja) * | 2020-03-27 | 2025-09-30 | ジェネレーション バイオ カンパニー | 新規脂質及びそれらのナノ粒子組成物 |
| IL298241A (en) * | 2020-05-18 | 2023-01-01 | Generation Bio Co | New lipids and their nanoparticle preparations |
-
2021
- 2021-07-16 AU AU2021307952A patent/AU2021307952A1/en active Pending
- 2021-07-16 KR KR1020237005643A patent/KR20230052895A/ko active Pending
- 2021-07-16 JP JP2023502945A patent/JP2023534043A/ja active Pending
- 2021-07-16 US US18/015,575 patent/US20230320993A1/en active Pending
- 2021-07-16 IL IL299896A patent/IL299896A/en unknown
- 2021-07-16 MX MX2023000806A patent/MX2023000806A/es unknown
- 2021-07-16 CN CN202180063144.XA patent/CN116437964A/zh active Pending
- 2021-07-16 EP EP21842533.8A patent/EP4181948A4/en active Pending
- 2021-07-16 CA CA3186033A patent/CA3186033A1/en active Pending
- 2021-07-16 WO PCT/US2021/042033 patent/WO2022016089A2/en not_active Ceased
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