|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US5885613A
(en)
|
1994-09-30 |
1999-03-23 |
The University Of British Columbia |
Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
|
|
US5928906A
(en)
|
1996-05-09 |
1999-07-27 |
Sequenom, Inc. |
Process for direct sequencing during template amplification
|
|
CA2289702C
(en)
|
1997-05-14 |
2008-02-19 |
Inex Pharmaceuticals Corp. |
High efficiency encapsulation of charged therapeutic agents in lipid vesicles
|
|
US6320017B1
(en)
|
1997-12-23 |
2001-11-20 |
Inex Pharmaceuticals Corp. |
Polyamide oligomers
|
|
US7201898B2
(en)
|
2000-06-01 |
2007-04-10 |
The University Of North Carolina At Chapel Hill |
Methods and compounds for controlled release of recombinant parvovirus vectors
|
|
US20030077829A1
(en)
|
2001-04-30 |
2003-04-24 |
Protiva Biotherapeutics Inc.. |
Lipid-based formulations
|
|
US7901708B2
(en)
|
2002-06-28 |
2011-03-08 |
Protiva Biotherapeutics, Inc. |
Liposomal apparatus and manufacturing methods
|
|
US20050164212A1
(en)
|
2003-03-06 |
2005-07-28 |
Todd Hauser |
Modulation of gene expression using DNA-RNA hybrids
|
|
US20050148531A1
(en)
|
2003-05-15 |
2005-07-07 |
Todd Hauser |
Modulation of gene expression using DNA-DNA hybrids
|
|
NZ592917A
(en)
|
2003-09-15 |
2012-12-21 |
Protiva Biotherapeutics Inc |
Stable polyethyleneglycol (PEG) dialkyloxypropyl (DAA) lipid conjugates
|
|
US7404969B2
(en)
|
2005-02-14 |
2008-07-29 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
|
US9005654B2
(en)
|
2005-07-27 |
2015-04-14 |
Protiva Biotherapeutics, Inc. |
Systems and methods for manufacturing liposomes
|
|
EP3192788A1
(en)
*
|
2006-10-03 |
2017-07-19 |
Arbutus Biopharma Corporation |
Lipid containing formulations
|
|
US20100015218A1
(en)
|
2007-02-16 |
2010-01-21 |
Vasant Jadhav |
Compositions and methods for potentiated activity of biologically active molecules
|
|
WO2009086558A1
(en)
|
2008-01-02 |
2009-07-09 |
Tekmira Pharmaceuticals Corporation |
Improved compositions and methods for the delivery of nucleic acids
|
|
AU2009238175C1
(en)
|
2008-04-15 |
2023-11-30 |
Arbutus Biopharma Corporation |
Novel lipid formulations for nucleic acid delivery
|
|
JP5642673B2
(ja)
|
2008-07-10 |
2014-12-17 |
セリナ・セラピユーテイツクス・インコーポレーテツド |
不活性末端基を有するポリオキサゾリン類、保護された開始基から調製されるポリオキサゾリン類及び関連化合物
|
|
MX342785B
(es)
|
2009-06-10 |
2016-10-12 |
Alnylam Pharmaceuticals Inc |
Formulacion mejorada de lipido.
|
|
EP2558074B1
(en)
|
2010-04-08 |
2018-06-06 |
The Trustees of Princeton University |
Preparation of lipid nanoparticles
|
|
WO2011139911A2
(en)
|
2010-04-29 |
2011-11-10 |
Isis Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
|
WO2012000104A1
(en)
|
2010-06-30 |
2012-01-05 |
Protiva Biotherapeutics, Inc. |
Non-liposomal systems for nucleic acid delivery
|
|
EA201390145A1
(ru)
|
2010-08-20 |
2013-11-29 |
Серулин Фарма Инк. |
Конъюгаты, частицы, композиции и связанные с ними способы
|
|
ES2888231T3
(es)
|
2010-09-20 |
2022-01-03 |
Sirna Therapeutics Inc |
Lípidos catiónicos de bajo peso molecular para el suministro de oligonucleótidos
|
|
EP2500434A1
(en)
*
|
2011-03-12 |
2012-09-19 |
Association Institut de Myologie |
Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
|
|
EP3354644A1
(en)
|
2011-06-08 |
2018-08-01 |
Translate Bio, Inc. |
Cleavable lipids
|
|
CA2853685C
(en)
|
2011-11-04 |
2019-09-03 |
Nitto Denko Corporation |
Single use system for sterilely producing lipid-nucleic acid particles
|
|
JP6093710B2
(ja)
|
2011-11-18 |
2017-03-08 |
日油株式会社 |
細胞内動態を改善したカチオン性脂質
|
|
HK1206644A1
(en)
|
2012-03-29 |
2016-01-15 |
Shire Human Genetic Therapies, Inc. |
Lipid-derived neutral nanoparticles
|
|
US9593077B2
(en)
|
2013-11-18 |
2017-03-14 |
Arcturus Therapeutics, Inc. |
Ionizable cationic lipid for RNA delivery
|
|
EP4019506A1
(en)
|
2013-12-19 |
2022-06-29 |
Novartis AG |
Lipids and lipid compositions for the delivery of active agents
|
|
SMT202200502T1
(it)
|
2014-06-25 |
2023-01-13 |
Acuitas Therapeutics Inc |
Nuovi lipidi e formulazioni di nanoparticelle lipidiche per l'erogazione di acidi nucleici
|
|
WO2016079197A1
(en)
*
|
2014-11-18 |
2016-05-26 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Delivery enhancers for conjugated sirna and lipid nanoparticles
|
|
CA2975371C
(en)
*
|
2015-01-30 |
2024-02-13 |
Nof Corporation |
Cationic lipid for nucleic acid delivery
|
|
LT3313829T
(lt)
|
2015-06-29 |
2024-08-12 |
Acuitas Therapeutics Inc. |
Lipidai ir lipidų nanodalelių sudėtys, skirtos nukleorūgščių tiekimui
|
|
IL307179A
(en)
|
2015-10-28 |
2023-11-01 |
Acuitas Therapeutics Inc |
Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
|
HRP20220652T1
(hr)
|
2015-12-10 |
2022-06-24 |
Modernatx, Inc. |
Pripravci i postupci unosa terapijskih sredstava
|
|
EP3397613A1
(en)
|
2015-12-30 |
2018-11-07 |
Acuitas Therapeutics Inc. |
Lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
|
EP3315125A1
(en)
*
|
2016-10-31 |
2018-05-02 |
Silence Therapeutics (London) Ltd |
Lipid nanoparticle formulation
|
|
WO2018237369A2
(en)
*
|
2017-06-23 |
2018-12-27 |
Vical Incorporated |
Lipid nanoparticle (lnp)-mediated delivery of a crispr-expressing plasmid dna for treating chronic hepatitis b virus infection
|
|
JP2020532981A
(ja)
*
|
2017-09-08 |
2020-11-19 |
ジェネレーション バイオ カンパニー |
修飾型閉端ｄｎａ（ｃｅｄｎａ）
|
|
AU2018330208B2
(en)
|
2017-09-08 |
2025-04-17 |
Generation Bio Co. |
Lipid nanoparticle formulations of non-viral, capsid-free DNA vectors
|
|
MA51842A
(fr)
*
|
2018-02-14 |
2020-12-23 |
Generation Bio Co |
Vecteurs d'adn non viraux et utilisations associées pour la production d'anticorps et de protéines de fusion
|
|
WO2019188867A1
(ja)
*
|
2018-03-27 |
2019-10-03 |
日油株式会社 |
細胞内動態を改善した新規カチオン性脂質
|