JP2023502576A5 - - Google Patents
Info
- Publication number
- JP2023502576A5 JP2023502576A5 JP2022524183A JP2022524183A JP2023502576A5 JP 2023502576 A5 JP2023502576 A5 JP 2023502576A5 JP 2022524183 A JP2022524183 A JP 2022524183A JP 2022524183 A JP2022524183 A JP 2022524183A JP 2023502576 A5 JP2023502576 A5 JP 2023502576A5
- Authority
- JP
- Japan
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962939326P | 2019-11-22 | 2019-11-22 | |
| US62/939,326 | 2019-11-22 | ||
| US202063026493P | 2020-05-18 | 2020-05-18 | |
| US63/026,493 | 2020-05-18 | ||
| PCT/US2020/061801 WO2021102411A1 (en) | 2019-11-22 | 2020-11-23 | Ionizable lipids and nanoparticle compositions thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023502576A JP2023502576A (ja) | 2023-01-25 |
| JPWO2021102411A5 JPWO2021102411A5 (https=) | 2023-12-01 |
| JP2023502576A5 true JP2023502576A5 (https=) | 2023-12-01 |
Family
ID=73854943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022524183A Pending JP2023502576A (ja) | 2019-11-22 | 2020-11-23 | イオン化可能な脂質およびそれらのナノ粒子組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220370357A1 (https=) |
| EP (1) | EP4061797A1 (https=) |
| JP (1) | JP2023502576A (https=) |
| CN (1) | CN114787127B (https=) |
| AU (1) | AU2020385378A1 (https=) |
| BR (1) | BR112022007481A2 (https=) |
| IL (2) | IL293039B2 (https=) |
| MX (1) | MX2022006033A (https=) |
| WO (1) | WO2021102411A1 (https=) |
Families Citing this family (26)
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| CN113166783B (zh) | 2018-10-09 | 2024-10-11 | 不列颠哥伦比亚大学 | 包含无有机溶剂和去污剂的转染活性囊泡的组合物和系统以及与之相关的方法 |
| US11613472B2 (en) * | 2019-07-22 | 2023-03-28 | King Fahd University Of Petroleum And Minerals | Dumbbell-shaped calcium hydroxide nanoparticles, an enhanced fuel comprising the nanoparticles, and a method for making |
| US20230181764A1 (en) * | 2020-05-18 | 2023-06-15 | Generation Bio Co. | Novel lipids and nanoparticle compositions thereof |
| MX2023000806A (es) * | 2020-07-17 | 2023-04-11 | Generation Bio Co | Métodos para encapsular polinucleótidos en tamaños reducidos de nanopartículas lipídicas y formulación novedosa de estos. |
| CN116234917A (zh) | 2020-07-27 | 2023-06-06 | 安杰瑞姆生物科学公司 | Dna分子组合物及其制备方法和使用方法 |
| IL303195A (en) | 2020-11-25 | 2023-07-01 | Akagera Medicines Inc | Lipid nanoparticles for delivery of nucleic acids and related methods of use |
| US12508225B2 (en) | 2021-05-28 | 2025-12-30 | Beijing Tricisionbio Therapeutics Inc. | Lipid compound and use thereof in delivery of nucleic acid |
| WO2022266032A1 (en) * | 2021-06-14 | 2022-12-22 | Generation Bio Co. | Cationic lipids and compositions thereof |
| EP4124348A1 (en) * | 2021-07-30 | 2023-02-01 | 4basebio UK Ltd | Nanoparticles for cell delivery |
| WO2023015200A1 (en) * | 2021-08-04 | 2023-02-09 | The Trustees Of The University Of Pennsylvania | Amniotic fluid stabilized compositions and methods for in utero delivery of therapeutic agents |
| EP4452942A1 (en) * | 2021-12-20 | 2024-10-30 | Beam Therapeutics Inc. | Nanomaterials comprising disulfides |
| EP4482819A2 (en) * | 2022-02-24 | 2025-01-01 | Vivasor, Inc. | Novel ionizable cationic lipids |
| WO2023183300A1 (en) * | 2022-03-22 | 2023-09-28 | The Children's Medical Center Corporation | Compositions and methods for prevention and treatment of genetic disease |
| AU2023275457A1 (en) | 2022-05-23 | 2024-11-28 | Astrazeneca Ab | Gene therapy compositions and methods of use thereof |
| EP4531819A2 (en) | 2022-05-25 | 2025-04-09 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids and methods of use thereof |
| EP4594299A1 (en) * | 2022-09-27 | 2025-08-06 | Reinvigoron TheraTech, Inc. | Compounds with cleavable disulfide moieties |
| WO2024081639A1 (en) * | 2022-10-11 | 2024-04-18 | Seawolf Therapeutics, Inc. | Novel lipid nanoparticle compositions for the delivery of nucleic acids |
| KR20250131271A (ko) | 2022-12-01 | 2025-09-02 | 제너레이션 바이오 컴퍼니 | 신규한 폴리글리세롤-접합된 지질 및 이를 포함하는 지질 나노입자 조성물 |
| EP4628496A1 (en) | 2022-12-29 | 2025-10-08 | Jenkem Technology Co., Ltd. (Liaoning) | Steroid-cationic lipid compound and use thereof |
| CN116444378A (zh) * | 2023-02-14 | 2023-07-18 | 广东优康精细化工有限公司 | 一种n-甲基异丙基胺的合成方法 |
| WO2024183497A1 (zh) * | 2023-03-09 | 2024-09-12 | 北京剂泰医药科技有限公司 | 一种鞘内递送制剂及其用途 |
| US12311033B2 (en) | 2023-05-31 | 2025-05-27 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| IL324725A (en) * | 2023-06-15 | 2026-01-01 | Serina Therapeutics Al Inc | Poly(oxazoline) conjugates with pendant cationic groups and lipid nanoparticles and polyplexes comprising them |
| WO2025124584A1 (zh) * | 2023-12-15 | 2025-06-19 | 厦门赛诺邦格生物科技股份有限公司 | 一种含二硫键的可降解阳离子脂质及其应用 |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| WO2026064512A1 (en) | 2024-09-18 | 2026-03-26 | Generation Bio Co. | Polyglycerol-conjugated lipids and lipid nanoparticle compositions comprising the same |
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| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5885613A (en) | 1994-09-30 | 1999-03-23 | The University Of British Columbia | Bilayer stabilizing components and their use in forming programmable fusogenic liposomes |
| US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
| CA2289702C (en) | 1997-05-14 | 2008-02-19 | Inex Pharmaceuticals Corp. | High efficiency encapsulation of charged therapeutic agents in lipid vesicles |
| US6320017B1 (en) | 1997-12-23 | 2001-11-20 | Inex Pharmaceuticals Corp. | Polyamide oligomers |
| US7201898B2 (en) | 2000-06-01 | 2007-04-10 | The University Of North Carolina At Chapel Hill | Methods and compounds for controlled release of recombinant parvovirus vectors |
| US20030077829A1 (en) | 2001-04-30 | 2003-04-24 | Protiva Biotherapeutics Inc.. | Lipid-based formulations |
| US7901708B2 (en) | 2002-06-28 | 2011-03-08 | Protiva Biotherapeutics, Inc. | Liposomal apparatus and manufacturing methods |
| NZ592917A (en) | 2003-09-15 | 2012-12-21 | Protiva Biotherapeutics Inc | Stable polyethyleneglycol (PEG) dialkyloxypropyl (DAA) lipid conjugates |
| US7404969B2 (en) | 2005-02-14 | 2008-07-29 | Sirna Therapeutics, Inc. | Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules |
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| WO2009086558A1 (en) | 2008-01-02 | 2009-07-09 | Tekmira Pharmaceuticals Corporation | Improved compositions and methods for the delivery of nucleic acids |
| AU2009238175C1 (en) | 2008-04-15 | 2023-11-30 | Arbutus Biopharma Corporation | Novel lipid formulations for nucleic acid delivery |
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| US9018187B2 (en) * | 2009-07-01 | 2015-04-28 | Protiva Biotherapeutics, Inc. | Cationic lipids and methods for the delivery of therapeutic agents |
| EP2558074B1 (en) | 2010-04-08 | 2018-06-06 | The Trustees of Princeton University | Preparation of lipid nanoparticles |
| WO2011139911A2 (en) | 2010-04-29 | 2011-11-10 | Isis Pharmaceuticals, Inc. | Lipid formulated single stranded rna |
| WO2012000104A1 (en) | 2010-06-30 | 2012-01-05 | Protiva Biotherapeutics, Inc. | Non-liposomal systems for nucleic acid delivery |
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| CA2853685C (en) | 2011-11-04 | 2019-09-03 | Nitto Denko Corporation | Single use system for sterilely producing lipid-nucleic acid particles |
| JP6093710B2 (ja) * | 2011-11-18 | 2017-03-08 | 日油株式会社 | 細胞内動態を改善したカチオン性脂質 |
| EP4019506A1 (en) | 2013-12-19 | 2022-06-29 | Novartis AG | Lipids and lipid compositions for the delivery of active agents |
| SMT202200502T1 (it) | 2014-06-25 | 2023-01-13 | Acuitas Therapeutics Inc | Nuovi lipidi e formulazioni di nanoparticelle lipidiche per l'erogazione di acidi nucleici |
| LT3313829T (lt) * | 2015-06-29 | 2024-08-12 | Acuitas Therapeutics Inc. | Lipidai ir lipidų nanodalelių sudėtys, skirtos nukleorūgščių tiekimui |
| IL307179A (en) | 2015-10-28 | 2023-11-01 | Acuitas Therapeutics Inc | Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids |
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| EP3397613A1 (en) | 2015-12-30 | 2018-11-07 | Acuitas Therapeutics Inc. | Lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| WO2018237369A2 (en) * | 2017-06-23 | 2018-12-27 | Vical Incorporated | Lipid nanoparticle (lnp)-mediated delivery of a crispr-expressing plasmid dna for treating chronic hepatitis b virus infection |
| AU2018330208B2 (en) * | 2017-09-08 | 2025-04-17 | Generation Bio Co. | Lipid nanoparticle formulations of non-viral, capsid-free DNA vectors |
| WO2019188867A1 (ja) | 2018-03-27 | 2019-10-03 | 日油株式会社 | 細胞内動態を改善した新規カチオン性脂質 |
-
2020
- 2020-11-23 AU AU2020385378A patent/AU2020385378A1/en active Pending
- 2020-11-23 US US17/642,314 patent/US20220370357A1/en active Pending
- 2020-11-23 MX MX2022006033A patent/MX2022006033A/es unknown
- 2020-11-23 EP EP20825350.0A patent/EP4061797A1/en active Pending
- 2020-11-23 IL IL293039A patent/IL293039B2/en unknown
- 2020-11-23 BR BR112022007481A patent/BR112022007481A2/pt unknown
- 2020-11-23 JP JP2022524183A patent/JP2023502576A/ja active Pending
- 2020-11-23 WO PCT/US2020/061801 patent/WO2021102411A1/en not_active Ceased
- 2020-11-23 CN CN202080079323.8A patent/CN114787127B/zh active Active
-
2025
- 2025-10-13 IL IL323923A patent/IL323923A/en unknown