JP2023531242A5 - - Google Patents
Info
- Publication number
- JP2023531242A5 JP2023531242A5 JP2022579677A JP2022579677A JP2023531242A5 JP 2023531242 A5 JP2023531242 A5 JP 2023531242A5 JP 2022579677 A JP2022579677 A JP 2022579677A JP 2022579677 A JP2022579677 A JP 2022579677A JP 2023531242 A5 JP2023531242 A5 JP 2023531242A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid residues
- amino acids
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063043883P | 2020-06-25 | 2020-06-25 | |
| EP20182139 | 2020-06-25 | ||
| US63/043,883 | 2020-06-25 | ||
| EP20182138.6 | 2020-06-25 | ||
| EP20182139.4 | 2020-06-25 | ||
| EP20182138 | 2020-06-25 | ||
| PCT/EP2021/066336 WO2021259742A1 (en) | 2020-06-25 | 2021-06-17 | Modified exotoxin a proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023531242A JP2023531242A (ja) | 2023-07-21 |
| JP2023531242A5 true JP2023531242A5 (https=) | 2024-06-21 |
Family
ID=76375084
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022579677A Pending JP2023531242A (ja) | 2020-06-25 | 2021-06-17 | 改変Ｅｘｏｔｏｘｉｎ Ａタンパク質 |
| JP2022580015A Active JP7847091B2 (ja) | 2020-06-25 | 2021-06-17 | 肺炎桿菌ｏ抗原ワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022580015A Active JP7847091B2 (ja) | 2020-06-25 | 2021-06-17 | 肺炎桿菌ｏ抗原ワクチン |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20230226175A1 (https=) |
| EP (2) | EP4171624A1 (https=) |
| JP (2) | JP2023531242A (https=) |
| CN (2) | CN116209753A (https=) |
| BR (2) | BR112022023234A2 (https=) |
| CA (2) | CA3185642A1 (https=) |
| MX (2) | MX2022015734A (https=) |
| WO (2) | WO2021259743A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240066109A1 (en) * | 2020-12-31 | 2024-02-29 | Vaxnewmo Llc | Klebsiella Pneumoniae O-Antigen Glycosylated Proteins and Methods of Making and Uses Thereof |
| US20240263132A1 (en) * | 2021-05-26 | 2024-08-08 | Pfizer Inc. | Recombinant expression of klebsiella pneumoniae o-antigens in escherichia coli |
| WO2023118033A1 (en) * | 2021-12-22 | 2023-06-29 | Glaxosmithkline Biologicals Sa | Vaccine |
| TW202432182A (zh) * | 2022-10-24 | 2024-08-16 | 瑞士商愛杜西亞製藥有限公司 | 對抗克雷伯氏肺炎桿菌之疫苗 |
| KR20250120353A (ko) * | 2022-12-08 | 2025-08-08 | 이도르시아 파마슈티컬스 리미티드 | 클렙시엘라 뉴모니아에의 백신 |
| WO2024146325A1 (zh) * | 2023-01-06 | 2024-07-11 | 中国人民解放军军事科学院军事医学研究院 | 用于生产抗原多糖-载体蛋白生物偶联产物的工程菌及其应用 |
| GB202302579D0 (en) * | 2023-02-23 | 2023-04-12 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| WO2025032534A2 (en) * | 2023-08-09 | 2025-02-13 | Glaxosmithkline Biologicals Sa | Modified proteins |
| CN120192388B (zh) * | 2025-03-04 | 2025-12-02 | 江西澄实生物科技有限公司 | 一种预防肺炎克雷伯氏菌感染的疫苗及其应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0027888B1 (en) | 1979-09-21 | 1986-04-16 | Hitachi, Ltd. | Semiconductor switch |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
| IT1187753B (it) | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5153312A (en) | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| ES2204900T3 (es) | 1992-02-11 | 2004-05-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Estructura inmuinogena de doble vector. |
| WO1995008348A1 (en) | 1993-09-22 | 1995-03-30 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method of activating soluble carbohydrate using novel cyanylating reagents for the production of immunogenic constructs |
| NZ304715A (en) | 1995-03-22 | 1999-07-29 | Jackson H M Found Military Med | Production of immunogenic constructs using organic cyanylating reagents to activate carbohydrates and then coupling the carbohydrate to a protein, peptide or hapten |
| IL163806A0 (en) | 2002-03-07 | 2005-12-18 | Eidgenoess Tech Hochschule | System and method for the production of recombinant glycosylated proteins in a prokaryotic host |
| US20070184072A1 (en) | 2005-04-08 | 2007-08-09 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| ES2353814T3 (es) | 2005-05-11 | 2011-03-07 | Eth Zuerich | Proteinas n-glicosiladas recombinantes de celulas procariotas. |
| CN101983070B (zh) | 2008-02-20 | 2016-03-30 | 格林考瓦因有限公司 | 由来源于原核细胞的重组n-糖基化蛋白制备生物共轭物 |
| JP2012533285A (ja) | 2009-07-17 | 2012-12-27 | オーシャン ハーベスト テクノロジー （カナダ） インコーポレイテッド | 魚用飼料中の合成添加物を置換する、天然かつ持続可能な海藻配合物 |
| NO2501406T3 (https=) | 2009-11-19 | 2018-05-19 | ||
| EP3281639B1 (en) | 2010-05-06 | 2020-11-11 | GlaxoSmithKline Biologicals S.A. | Capsular gram-positive bacteria bioconjugate vaccines |
| BR112015004817A2 (pt) | 2012-09-10 | 2017-07-04 | Glycovaxyn Ag | bioconjugados compreendendo antígenos modificados e seus usos |
| ES2905107T3 (es) | 2012-10-12 | 2022-04-07 | Glaxosmithkline Biologicals Sa | Procedimientos de modificación de células hospedadoras |
| EP3508579B1 (en) | 2012-11-07 | 2021-06-30 | GlaxoSmithKline Biologicals SA | Production of recombinant vaccine in e. coli by enzymatic conjugation |
| GB201301085D0 (en) * | 2013-01-22 | 2013-03-06 | London School Hygiene & Tropical Medicine | Glycoconjugate Vaccine |
| MX371513B (es) * | 2013-10-11 | 2020-01-31 | Glaxosmithkline Biologicals Sa | Metodos de modificacion de celulas huespedes. |
| WO2015124769A1 (en) | 2014-02-24 | 2015-08-27 | Glycovaxyn Ag | Novel polysaccharide and uses thereof |
| WO2016020499A2 (en) | 2014-08-08 | 2016-02-11 | Glycovaxyn Ag | Modified host cells for use in bioconjugate production |
| US9988426B2 (en) * | 2014-09-18 | 2018-06-05 | University Of Maryland, Baltimore | Broad spectrum conjugate vaccine to prevent Klebsiella pneumoniae and Pseudomonas aeruginosa infections |
| TWI715617B (zh) | 2015-08-24 | 2021-01-11 | 比利時商葛蘭素史密斯克藍生物品公司 | 對抗腸道外病原性大腸桿菌之免疫保護之方法及組合物 |
| GB201712678D0 (en) | 2017-08-07 | 2017-09-20 | Glaxosmithkline Biologicals Sa | Process for the manipulation of nucleic acids |
| EP3492481A1 (en) * | 2017-11-30 | 2019-06-05 | Vaxxilon AG | Vaccine against klebsiella pneumoniae |
| JP2021528059A (ja) * | 2018-06-16 | 2021-10-21 | ヴァックスニューモ エルエルシーＶａｘｎｅｗｍｏ Ｌｌｃ | グリコシル化されたＣｏｍＰピリンバリアント、製造方法及びその使用 |
| BR112022014555A2 (pt) * | 2020-02-23 | 2022-09-20 | Pfizer | Composições de escherichia coli e métodos das mesmas. |
-
2021
- 2021-06-17 WO PCT/EP2021/066343 patent/WO2021259743A2/en not_active Ceased
- 2021-06-17 CN CN202180044800.1A patent/CN116209753A/zh active Pending
- 2021-06-17 WO PCT/EP2021/066336 patent/WO2021259742A1/en not_active Ceased
- 2021-06-17 CA CA3185642A patent/CA3185642A1/en active Pending
- 2021-06-17 BR BR112022023234A patent/BR112022023234A2/pt unknown
- 2021-06-17 CA CA3185639A patent/CA3185639A1/en active Pending
- 2021-06-17 BR BR112022024267A patent/BR112022024267A2/pt unknown
- 2021-06-17 MX MX2022015734A patent/MX2022015734A/es unknown
- 2021-06-17 US US18/001,498 patent/US20230226175A1/en active Pending
- 2021-06-17 EP EP21731533.2A patent/EP4171624A1/en active Pending
- 2021-06-17 EP EP21731535.7A patent/EP4171625A2/en active Pending
- 2021-06-17 JP JP2022579677A patent/JP2023531242A/ja active Pending
- 2021-06-17 JP JP2022580015A patent/JP7847091B2/ja active Active
- 2021-06-17 US US18/001,525 patent/US20230293657A1/en active Pending
- 2021-06-17 CN CN202180045684.5A patent/CN115996749A/zh active Pending
- 2021-06-17 MX MX2022016589A patent/MX2022016589A/es unknown
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