JP2021528059A5 - - Google Patents
Info
- Publication number
- JP2021528059A5 JP2021528059A5 JP2020569986A JP2020569986A JP2021528059A5 JP 2021528059 A5 JP2021528059 A5 JP 2021528059A5 JP 2020569986 A JP2020569986 A JP 2020569986A JP 2020569986 A JP2020569986 A JP 2020569986A JP 2021528059 A5 JP2021528059 A5 JP 2021528059A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- comp
- glycosylated
- polysaccharide
- tag
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024061674A JP2024079845A (ja) | 2018-06-16 | 2024-04-05 | グリコシル化されたＣｏｍＰピリンバリアント、製造方法及びその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862685970P | 2018-06-16 | 2018-06-16 | |
| US62/685,970 | 2018-06-16 | ||
| US201862783971P | 2018-12-21 | 2018-12-21 | |
| US62/783,971 | 2018-12-21 | ||
| PCT/US2019/037251 WO2019241672A2 (en) | 2018-06-16 | 2019-06-14 | Glycosylated comp pilin variants, methods of making and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024061674A Division JP2024079845A (ja) | 2018-06-16 | 2024-04-05 | グリコシル化されたＣｏｍＰピリンバリアント、製造方法及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021528059A JP2021528059A (ja) | 2021-10-21 |
| JP2021528059A5 true JP2021528059A5 (https=) | 2022-06-22 |
| JPWO2019241672A5 JPWO2019241672A5 (https=) | 2022-06-22 |
Family
ID=68843212
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020569986A Pending JP2021528059A (ja) | 2018-06-16 | 2019-06-14 | グリコシル化されたＣｏｍＰピリンバリアント、製造方法及びその使用 |
| JP2024061674A Pending JP2024079845A (ja) | 2018-06-16 | 2024-04-05 | グリコシル化されたＣｏｍＰピリンバリアント、製造方法及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024061674A Pending JP2024079845A (ja) | 2018-06-16 | 2024-04-05 | グリコシル化されたＣｏｍＰピリンバリアント、製造方法及びその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11932670B2 (https=) |
| EP (1) | EP3806881B1 (https=) |
| JP (2) | JP2021528059A (https=) |
| AU (1) | AU2019287659B2 (https=) |
| CA (1) | CA3103474A1 (https=) |
| ES (1) | ES3051337T3 (https=) |
| WO (1) | WO2019241672A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3262077B1 (en) | 2015-02-26 | 2025-06-04 | Vaxnewmo Llc | Acinetobacter o-oligosaccharyltransferases and uses thereof |
| US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
| WO2019241672A2 (en) | 2018-06-16 | 2019-12-19 | Vaxnewmo Llc | Glycosylated comp pilin variants, methods of making and uses thereof |
| ES3055827T3 (en) | 2018-12-21 | 2026-02-16 | Vaxnewmo Llc | O-linked glycosylation recognition motifs |
| EP4171625A2 (en) * | 2020-06-25 | 2023-05-03 | GlaxoSmithKline Biologicals SA | Klebsiella pneumoniae o-antigen vaccine |
| EP4271417A4 (en) * | 2020-12-31 | 2024-11-27 | Vaxnewmo Llc | GLYCOSYLATED KLEBSIELLA PNEUMONIAE O-ANTIGEN AND METHODS OF PREPARATION AND USES THEREOF |
| CA3215046A1 (en) * | 2021-04-28 | 2022-11-03 | Vaxnewmo Llc | Minimal sequons sufficient for o-linking glycosylation |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2671709C (en) | 2006-12-13 | 2016-08-16 | The Governors Of The University Of Alberta | Methods and systems for o-glycosylating proteins |
| WO2011109600A1 (en) | 2010-03-05 | 2011-09-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for modifying the glycosylation pattern of a polypeptide |
| EP2742355B1 (en) | 2011-08-12 | 2018-12-19 | The Governors of the University of Alberta | Method of diagnosing bacterial infections using bacterial glycoproteins |
| CN104080921A (zh) | 2011-11-04 | 2014-10-01 | 康奈尔大学 | 一种用于糖蛋白合成的基于原核生物的无细胞系统 |
| CN110423716A (zh) | 2012-10-12 | 2019-11-08 | 葛兰素史密丝克莱恩生物有限公司 | 宿主细胞修饰方法 |
| CA2889767C (en) * | 2012-11-07 | 2021-09-21 | Glycovaxyn Ag | Production of recombinant vaccine in e. coli by enzymatic conjugation |
| WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
| WO2014195011A1 (en) | 2013-06-04 | 2014-12-11 | Icon Genetics Gmbh | Methods of modulating n-glycosylation site occupancy of plant-produced glycoproteins and recombinant glycoproteins |
| US9988426B2 (en) | 2014-09-18 | 2018-06-05 | University Of Maryland, Baltimore | Broad spectrum conjugate vaccine to prevent Klebsiella pneumoniae and Pseudomonas aeruginosa infections |
| LT3240895T (lt) | 2014-12-30 | 2022-04-11 | Glaxosmithkline Biologicals S.A. | Kompozicijos ir būdai, skirti baltymų glikozilinimui |
| EP3262077B1 (en) * | 2015-02-26 | 2025-06-04 | Vaxnewmo Llc | Acinetobacter o-oligosaccharyltransferases and uses thereof |
| US11279943B2 (en) | 2017-01-17 | 2022-03-22 | Bioapplications Inc. | Recombinant vector for expressing target protein in plant cell |
| EP3492481A1 (en) | 2017-11-30 | 2019-06-05 | Vaxxilon AG | Vaccine against klebsiella pneumoniae |
| WO2019241672A2 (en) | 2018-06-16 | 2019-12-19 | Vaxnewmo Llc | Glycosylated comp pilin variants, methods of making and uses thereof |
| US20220054632A1 (en) | 2018-12-12 | 2022-02-24 | Glaxosmithkline Biologicals Sa | Modified carrier proteins for o-linked glycosylation |
| ES3055827T3 (en) | 2018-12-21 | 2026-02-16 | Vaxnewmo Llc | O-linked glycosylation recognition motifs |
-
2019
- 2019-06-14 WO PCT/US2019/037251 patent/WO2019241672A2/en not_active Ceased
- 2019-06-14 CA CA3103474A patent/CA3103474A1/en active Pending
- 2019-06-14 JP JP2020569986A patent/JP2021528059A/ja active Pending
- 2019-06-14 EP EP19820087.5A patent/EP3806881B1/en active Active
- 2019-06-14 ES ES19820087T patent/ES3051337T3/es active Active
- 2019-06-14 AU AU2019287659A patent/AU2019287659B2/en active Active
- 2019-06-14 US US17/251,994 patent/US11932670B2/en active Active
-
2024
- 2024-03-14 US US18/605,436 patent/US12577280B2/en active Active
- 2024-04-05 JP JP2024061674A patent/JP2024079845A/ja active Pending
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