JP2023529177A - アウトサイドイン透析用途のための中空繊維 - Google Patents

アウトサイドイン透析用途のための中空繊維 Download PDF

Info

Publication number
JP2023529177A
JP2023529177A JP2022574812A JP2022574812A JP2023529177A JP 2023529177 A JP2023529177 A JP 2023529177A JP 2022574812 A JP2022574812 A JP 2022574812A JP 2022574812 A JP2022574812 A JP 2022574812A JP 2023529177 A JP2023529177 A JP 2023529177A
Authority
JP
Japan
Prior art keywords
fiber
fibers
porous hollow
macrovoids
hollow fiber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022574812A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023529177A5 (enExample
Inventor
イラリア・ジェレミア
ディミトリオス・スタマティアリス
モハメド・ラビブ
ピーター・マテルナ
Original Assignee
ノヴァフラックス・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノヴァフラックス・インコーポレイテッド filed Critical ノヴァフラックス・インコーポレイテッド
Publication of JP2023529177A publication Critical patent/JP2023529177A/ja
Publication of JP2023529177A5 publication Critical patent/JP2023529177A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F8/00—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof
    • D01F8/04—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof from synthetic polymers
    • D01F8/16—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof from synthetic polymers with at least one other macromolecular compound obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds as constituent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • B01D69/085—Details relating to the spinneret
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1623—Disposition or location of membranes relative to fluids
    • A61M1/1625—Dialyser of the outside perfusion type, i.e. blood flow outside hollow membrane fibres or tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0002—Organic membrane manufacture
    • B01D67/0009—Organic membrane manufacture by phase separation, sol-gel transition, evaporation or solvent quenching
    • B01D67/0016—Coagulation
    • B01D67/00165—Composition of the coagulation baths
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • B01D69/087—Details relating to the spinning process
    • B01D69/0871—Fibre guidance after spinning through the manufacturing apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/66—Polymers having sulfur in the main chain, with or without nitrogen, oxygen or carbon only
    • B01D71/68—Polysulfones; Polyethersulfones
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/06—Wet spinning methods
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/24—Formation of filaments, threads, or the like with a hollow structure; Spinnerette packs therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0415—Plasma
    • A61M2202/0421—Beta-2-microglobulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7527—General characteristics of the apparatus with filters liquophilic, hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/08—Specific temperatures applied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/15—Use of additives
    • B01D2323/218—Additive materials
    • B01D2323/2182—Organic additives
    • B01D2323/21839—Polymeric additives
    • B01D2323/2185—Polyethylene glycol
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/15—Use of additives
    • B01D2323/218—Additive materials
    • B01D2323/2182—Organic additives
    • B01D2323/21839—Polymeric additives
    • B01D2323/2187—Polyvinylpyrolidone
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/219—Specific solvent system
    • B01D2323/22—Specific non-solvents or non-solvent system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/02—Details relating to pores or porosity of the membranes
    • B01D2325/022—Asymmetric membranes
    • B01D2325/0231—Dense layers being placed on the outer side of the cross-section
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/02—Details relating to pores or porosity of the membranes
    • B01D2325/025—Finger pores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/20—Specific permeability or cut-off range
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00—Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • D10B2331/06—Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyethers
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00—Physical properties
    • D10B2401/02—Moisture-responsive characteristics
    • D10B2401/022—Moisture-responsive characteristics hydrophylic
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00—Physical properties
    • D10B2401/10—Physical properties porous
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2509/00—Medical; Hygiene

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Textile Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
JP2022574812A 2020-06-04 2021-06-04 アウトサイドイン透析用途のための中空繊維 Pending JP2023529177A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063034790P 2020-06-04 2020-06-04
US63/034,790 2020-06-04
PCT/US2021/035945 WO2021248028A1 (en) 2020-06-04 2021-06-04 Hollow fibers for outside-in dialysis applications

Publications (2)

Publication Number Publication Date
JP2023529177A true JP2023529177A (ja) 2023-07-07
JP2023529177A5 JP2023529177A5 (enExample) 2024-06-11

Family

ID=76695862

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022574812A Pending JP2023529177A (ja) 2020-06-04 2021-06-04 アウトサイドイン透析用途のための中空繊維

Country Status (4)

Country Link
US (1) US20210381131A1 (enExample)
EP (1) EP4161688A1 (enExample)
JP (1) JP2023529177A (enExample)
WO (1) WO2021248028A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025101550A1 (en) * 2023-11-07 2025-05-15 Fresenius Medical Care Holdings, Inc. Small diameter hollow fiber membrane and methods for making the same
US20250257497A1 (en) * 2024-02-09 2025-08-14 Moleaer, Inc. Nanobubbles for preparation of spun fibrous materials

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61164602A (ja) * 1985-01-17 1986-07-25 Daicel Chem Ind Ltd ポリスルホン系樹脂製中空糸膜
JPH08508935A (ja) * 1994-02-09 1996-09-24 バクスター、インターナショナル、インコーポレイテッド 揺動濾過装置によって溶質を濃縮するための方法
JP2006510483A (ja) * 2002-12-20 2006-03-30 ガンブロ・ルンディア・エービー 選択透過性膜およびその製造のための方法
JP2012527341A (ja) * 2009-05-20 2012-11-08 ガンブロ・ルンディア・エービー 改良された性能を有する膜

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58132111A (ja) * 1982-01-29 1983-08-06 Asahi Chem Ind Co Ltd ポリスルホン中空糸
JP3934340B2 (ja) * 1998-11-09 2007-06-20 旭化成メディカル株式会社 血液浄化器
JP2001162143A (ja) * 1999-12-07 2001-06-19 Nikkiso Co Ltd 医療用中空糸膜、及びその製造方法
US7585412B2 (en) 2000-04-13 2009-09-08 Transvivo, Inc. Specialized hollow fiber membranes for plasmapheresis and ultrafiltration
SE0203855L (sv) 2002-12-20 2004-06-21 Gambro Lundia Ab Permselektivt membran
EP1710011A1 (en) * 2005-04-07 2006-10-11 Gambro Lundia AB Filtration membrane
DE602007010505D1 (de) * 2006-10-18 2010-12-23 Gambro Lundia Ab Hohlfasermembran und verfahren zu ihrer herstellung
US9352283B2 (en) * 2010-10-25 2016-05-31 Agency For Science, Technology And Research Tubular fiber membrane with nanoporous skin
HK1224245A1 (zh) * 2014-02-06 2017-08-18 甘布罗伦迪亚股份公司 用於血液净化的膜
US10369263B2 (en) 2014-03-29 2019-08-06 Novaflux Inc. Blood processing cartridges and systems, and methods for extracorporeal blood therapies
US10399040B2 (en) 2015-09-24 2019-09-03 Novaflux Inc. Cartridges and systems for membrane-based therapies
KR20190060553A (ko) * 2017-11-24 2019-06-03 롯데케미칼 주식회사 중공사막 및 이의 제조방법

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61164602A (ja) * 1985-01-17 1986-07-25 Daicel Chem Ind Ltd ポリスルホン系樹脂製中空糸膜
JPH08508935A (ja) * 1994-02-09 1996-09-24 バクスター、インターナショナル、インコーポレイテッド 揺動濾過装置によって溶質を濃縮するための方法
JP2006510483A (ja) * 2002-12-20 2006-03-30 ガンブロ・ルンディア・エービー 選択透過性膜およびその製造のための方法
JP2012527341A (ja) * 2009-05-20 2012-11-08 ガンブロ・ルンディア・エービー 改良された性能を有する膜

Also Published As

Publication number Publication date
US20210381131A1 (en) 2021-12-09
WO2021248028A1 (en) 2021-12-09
EP4161688A1 (en) 2023-04-12

Similar Documents

Publication Publication Date Title
JP3047403B2 (ja) 血液透析に適当な透過選択性不均斉膜および該膜の製造方法
JP5065379B2 (ja) 限外濾過膜
JP2916446B2 (ja) 非対称微孔性中空繊維の製造方法
JP6698536B2 (ja) 血液浄化のための膜
EP3102312B1 (en) Hemodialyzer for blood purification
JP5720249B2 (ja) 中空糸膜およびその製造方法および血液浄化モジュール
US20060234582A1 (en) Permselective membrane and process for manufacturing thereof
JPWO2009072548A1 (ja) 血液処理用多孔質中空糸膜
EP0716859B1 (en) Module for blood purification, blood purification membrane and its production
JP2006217929A (ja) 高透水性中空糸膜型血液浄化器
WO2012106583A2 (en) Performance enhancing additives for fiber formation and polysulfone fibers
US20210381131A1 (en) Hollow fibers for outside-in-dialysis applications
JP2020533166A (ja) 微多孔膜およびその作製方法
JP5217238B2 (ja) 透過性能安定性に優れた多孔質中空糸膜および血液浄化器
JP2011050881A (ja) 中空糸膜の紡糸方法
JP4036740B2 (ja) 中空糸型血液浄化膜の製造方法
JP4093134B2 (ja) 中空糸型血液浄化膜
JP2005021510A (ja) 高透水性中空糸型血液浄化器
JP5299617B2 (ja) 中空糸膜の製造方法
Elsen et al. Advantages of meltspun membrane technology compared to solution spinning
JP2000107577A (ja) 選択透過性中空糸膜の製造方法
JP4386607B2 (ja) ポリスルホン系血液浄化膜の製造方法およびポリスルホン系血液浄化膜
JP2011024708A (ja) モジュール組み立て性に優れた血液浄化用中空糸膜およびその製造方法
JP2011020071A (ja) ポリスルホン系中空糸膜の製造方法
JP2009078121A (ja) 血液浄化器及びその製造方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240603

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20240603

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20250226

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250401

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20250930