JP2023528659A5 - - Google Patents

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Publication number
JP2023528659A5
JP2023528659A5 JP2022575408A JP2022575408A JP2023528659A5 JP 2023528659 A5 JP2023528659 A5 JP 2023528659A5 JP 2022575408 A JP2022575408 A JP 2022575408A JP 2022575408 A JP2022575408 A JP 2022575408A JP 2023528659 A5 JP2023528659 A5 JP 2023528659A5
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JP
Japan
Prior art keywords
compound according
alkyl
alkenyl
alkynyl
cyano
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022575408A
Other languages
English (en)
Japanese (ja)
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JP2023528659A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/036398 external-priority patent/WO2021252488A1/en
Publication of JP2023528659A publication Critical patent/JP2023528659A/ja
Publication of JP2023528659A5 publication Critical patent/JP2023528659A5/ja
Pending legal-status Critical Current

Links

JP2022575408A 2020-06-08 2021-06-08 Nek7キナーゼの阻害剤 Pending JP2023528659A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063036244P 2020-06-08 2020-06-08
US63/036,244 2020-06-08
US202163170776P 2021-04-05 2021-04-05
US63/170,776 2021-04-05
US202163185257P 2021-05-06 2021-05-06
US63/185,257 2021-05-06
PCT/US2021/036398 WO2021252488A1 (en) 2020-06-08 2021-06-08 Inhibitors of nek7 kinase

Publications (2)

Publication Number Publication Date
JP2023528659A JP2023528659A (ja) 2023-07-05
JP2023528659A5 true JP2023528659A5 (https=) 2024-06-13

Family

ID=76731040

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022575408A Pending JP2023528659A (ja) 2020-06-08 2021-06-08 Nek7キナーゼの阻害剤

Country Status (13)

Country Link
US (1) US20230203045A1 (https=)
EP (1) EP4161933A1 (https=)
JP (1) JP2023528659A (https=)
KR (1) KR20230035311A (https=)
CN (1) CN116075513A (https=)
AU (1) AU2021289345A1 (https=)
BR (1) BR112022025012A2 (https=)
CA (1) CA3186041A1 (https=)
CO (1) CO2022019131A2 (https=)
IL (1) IL298849A (https=)
MX (1) MX2022015495A (https=)
TW (1) TWI908811B (https=)
WO (1) WO2021252488A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS65962B1 (sr) 2020-05-08 2024-10-31 Halia Therapeutics Inc Inhibitori nek7 kinaze
US20240400551A1 (en) * 2021-01-25 2024-12-05 Halia Therapeutics, Inc. Nek7 inhibitors
US20240158394A1 (en) * 2022-09-14 2024-05-16 Halia Therapeutics, Inc. Nek7 inhibitors
WO2025140570A1 (zh) * 2023-12-29 2025-07-03 北京普祺医药科技股份有限公司 一种nek7抑制剂、药物组合物及其用途

Family Cites Families (19)

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US5052558A (en) 1987-12-23 1991-10-01 Entravision, Inc. Packaged pharmaceutical product
US5033252A (en) 1987-12-23 1991-07-23 Entravision, Inc. Method of packaging and sterilizing a pharmaceutical product
US5323907A (en) 1992-06-23 1994-06-28 Multi-Comp, Inc. Child resistant package assembly for dispensing pharmaceutical medications
MXPA03008560A (es) 2001-03-22 2004-06-30 Abbot Gmbh & Co Kg Pirazolopirimidinas como agentes terapeuticos.
US20110189167A1 (en) 2007-04-20 2011-08-04 Flynn Daniel L Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases
UY33288A (es) 2010-03-25 2011-10-31 Glaxosmithkline Llc Derivados de indolina inhibidores de la proteina quinasa r del reticulo endoplasmatico
EP2802212B1 (en) 2012-01-12 2015-12-30 Basf Se Herbicidal isoxazolo[5,4-b]pyridines
CN105017256A (zh) 2014-04-29 2015-11-04 浙江导明医药科技有限公司 多氟化合物作为布鲁顿酪氨酸激酶抑制剂
RU2724345C2 (ru) 2015-10-09 2020-06-23 Галапагос Нв N-СУЛЬФОНИЛИРОВАННЫЕ ПИРАЗОЛО[3,4-b]ПИРИДИН-6-КАРБОКСАМИДЫ И СПОСОБ ИХ ПРИМЕНЕНИЯ
CN108250200A (zh) 2016-12-28 2018-07-06 中国科学院上海药物研究所 一种具有Axl抑制活性的化合物及其制备和应用
DE102017200543A1 (de) 2017-01-13 2018-07-19 Baden-Württemberg Stiftung Ggmbh Verfahren zur Behandlung einer Oberfläche eines Hartmetallkörpers und zur Beschichtung des behandelten Hartmetallkörpers mit einer Diamantschicht
DE102017118230B4 (de) * 2017-08-10 2021-04-22 Christoph Lucks Verfahren zur Analyse und/oder Überwachung von Brücken sowie entsprechendes System und entsprechende Verwendung
MX2020001776A (es) * 2017-08-15 2020-03-24 Inflazome Ltd Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3.
KR20200087759A (ko) 2017-11-09 2020-07-21 인플라좀 리미티드 신규한 설폰아마이드 카복스아마이드 화합물
IL277408B2 (en) * 2018-04-05 2024-08-01 Merck Patent Gmbh Heteroaryl compounds as IRAK type II inhibitors and their use
AR118119A1 (es) 2019-02-18 2021-09-22 Genentech Inc Compuestos de pirido-pirimidinilo y métodos de uso
CN111646995B (zh) * 2019-03-04 2023-03-21 四川大学 4-氨基-嘧啶并氮杂环-苯基脲类衍生物及其制备方法和用途
WO2021057877A1 (zh) * 2019-09-26 2021-04-01 深圳市塔吉瑞生物医药有限公司 取代的芳香稠合环衍生物及其组合物及用途
AU2020436612A1 (en) * 2020-03-16 2022-09-01 Flash Therapeutics, Llc Compounds for treating or inhibiting recurrence of acute myeloid leukemia

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