CO2022019131A2 - Inhibidores de la quinasa nek7 - Google Patents
Inhibidores de la quinasa nek7Info
- Publication number
- CO2022019131A2 CO2022019131A2 CONC2022/0019131A CO2022019131A CO2022019131A2 CO 2022019131 A2 CO2022019131 A2 CO 2022019131A2 CO 2022019131 A CO2022019131 A CO 2022019131A CO 2022019131 A2 CO2022019131 A2 CO 2022019131A2
- Authority
- CO
- Colombia
- Prior art keywords
- nek7
- compounds
- kinase inhibitors
- activity
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063036244P | 2020-06-08 | 2020-06-08 | |
| US202163170776P | 2021-04-05 | 2021-04-05 | |
| US202163185257P | 2021-05-06 | 2021-05-06 | |
| PCT/US2021/036398 WO2021252488A1 (en) | 2020-06-08 | 2021-06-08 | Inhibitors of nek7 kinase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2022019131A2 true CO2022019131A2 (es) | 2023-03-07 |
Family
ID=76731040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2022/0019131A CO2022019131A2 (es) | 2020-06-08 | 2022-12-28 | Inhibidores de la quinasa nek7 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230203045A1 (https=) |
| EP (1) | EP4161933A1 (https=) |
| JP (1) | JP2023528659A (https=) |
| KR (1) | KR20230035311A (https=) |
| CN (1) | CN116075513A (https=) |
| AU (1) | AU2021289345A1 (https=) |
| BR (1) | BR112022025012A2 (https=) |
| CA (1) | CA3186041A1 (https=) |
| CO (1) | CO2022019131A2 (https=) |
| IL (1) | IL298849A (https=) |
| MX (1) | MX2022015495A (https=) |
| TW (1) | TWI908811B (https=) |
| WO (1) | WO2021252488A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS65962B1 (sr) | 2020-05-08 | 2024-10-31 | Halia Therapeutics Inc | Inhibitori nek7 kinaze |
| US20240400551A1 (en) * | 2021-01-25 | 2024-12-05 | Halia Therapeutics, Inc. | Nek7 inhibitors |
| US20240158394A1 (en) * | 2022-09-14 | 2024-05-16 | Halia Therapeutics, Inc. | Nek7 inhibitors |
| WO2025140570A1 (zh) * | 2023-12-29 | 2025-07-03 | 北京普祺医药科技股份有限公司 | 一种nek7抑制剂、药物组合物及其用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5052558A (en) | 1987-12-23 | 1991-10-01 | Entravision, Inc. | Packaged pharmaceutical product |
| US5033252A (en) | 1987-12-23 | 1991-07-23 | Entravision, Inc. | Method of packaging and sterilizing a pharmaceutical product |
| US5323907A (en) | 1992-06-23 | 1994-06-28 | Multi-Comp, Inc. | Child resistant package assembly for dispensing pharmaceutical medications |
| MXPA03008560A (es) | 2001-03-22 | 2004-06-30 | Abbot Gmbh & Co Kg | Pirazolopirimidinas como agentes terapeuticos. |
| US20110189167A1 (en) | 2007-04-20 | 2011-08-04 | Flynn Daniel L | Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases |
| UY33288A (es) | 2010-03-25 | 2011-10-31 | Glaxosmithkline Llc | Derivados de indolina inhibidores de la proteina quinasa r del reticulo endoplasmatico |
| EP2802212B1 (en) | 2012-01-12 | 2015-12-30 | Basf Se | Herbicidal isoxazolo[5,4-b]pyridines |
| CN105017256A (zh) | 2014-04-29 | 2015-11-04 | 浙江导明医药科技有限公司 | 多氟化合物作为布鲁顿酪氨酸激酶抑制剂 |
| RU2724345C2 (ru) | 2015-10-09 | 2020-06-23 | Галапагос Нв | N-СУЛЬФОНИЛИРОВАННЫЕ ПИРАЗОЛО[3,4-b]ПИРИДИН-6-КАРБОКСАМИДЫ И СПОСОБ ИХ ПРИМЕНЕНИЯ |
| CN108250200A (zh) | 2016-12-28 | 2018-07-06 | 中国科学院上海药物研究所 | 一种具有Axl抑制活性的化合物及其制备和应用 |
| DE102017200543A1 (de) | 2017-01-13 | 2018-07-19 | Baden-Württemberg Stiftung Ggmbh | Verfahren zur Behandlung einer Oberfläche eines Hartmetallkörpers und zur Beschichtung des behandelten Hartmetallkörpers mit einer Diamantschicht |
| DE102017118230B4 (de) * | 2017-08-10 | 2021-04-22 | Christoph Lucks | Verfahren zur Analyse und/oder Überwachung von Brücken sowie entsprechendes System und entsprechende Verwendung |
| MX2020001776A (es) * | 2017-08-15 | 2020-03-24 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3. |
| KR20200087759A (ko) | 2017-11-09 | 2020-07-21 | 인플라좀 리미티드 | 신규한 설폰아마이드 카복스아마이드 화합물 |
| IL277408B2 (en) * | 2018-04-05 | 2024-08-01 | Merck Patent Gmbh | Heteroaryl compounds as IRAK type II inhibitors and their use |
| AR118119A1 (es) | 2019-02-18 | 2021-09-22 | Genentech Inc | Compuestos de pirido-pirimidinilo y métodos de uso |
| CN111646995B (zh) * | 2019-03-04 | 2023-03-21 | 四川大学 | 4-氨基-嘧啶并氮杂环-苯基脲类衍生物及其制备方法和用途 |
| WO2021057877A1 (zh) * | 2019-09-26 | 2021-04-01 | 深圳市塔吉瑞生物医药有限公司 | 取代的芳香稠合环衍生物及其组合物及用途 |
| AU2020436612A1 (en) * | 2020-03-16 | 2022-09-01 | Flash Therapeutics, Llc | Compounds for treating or inhibiting recurrence of acute myeloid leukemia |
-
2021
- 2021-06-08 EP EP21736837.2A patent/EP4161933A1/en active Pending
- 2021-06-08 JP JP2022575408A patent/JP2023528659A/ja active Pending
- 2021-06-08 KR KR1020237000263A patent/KR20230035311A/ko active Pending
- 2021-06-08 IL IL298849A patent/IL298849A/en unknown
- 2021-06-08 WO PCT/US2021/036398 patent/WO2021252488A1/en not_active Ceased
- 2021-06-08 BR BR112022025012A patent/BR112022025012A2/pt unknown
- 2021-06-08 US US18/001,064 patent/US20230203045A1/en active Pending
- 2021-06-08 AU AU2021289345A patent/AU2021289345A1/en active Pending
- 2021-06-08 TW TW110120796A patent/TWI908811B/zh active
- 2021-06-08 MX MX2022015495A patent/MX2022015495A/es unknown
- 2021-06-08 CN CN202180057370.7A patent/CN116075513A/zh active Pending
- 2021-06-08 CA CA3186041A patent/CA3186041A1/en active Pending
-
2022
- 2022-12-28 CO CONC2022/0019131A patent/CO2022019131A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112022025012A2 (pt) | 2023-02-14 |
| CN116075513A (zh) | 2023-05-05 |
| US20230203045A1 (en) | 2023-06-29 |
| IL298849A (en) | 2023-02-01 |
| KR20230035311A (ko) | 2023-03-13 |
| WO2021252488A1 (en) | 2021-12-16 |
| CA3186041A1 (en) | 2021-12-16 |
| JP2023528659A (ja) | 2023-07-05 |
| TW202208368A (zh) | 2022-03-01 |
| EP4161933A1 (en) | 2023-04-12 |
| AU2021289345A1 (en) | 2023-01-19 |
| MX2022015495A (es) | 2023-03-14 |
| TWI908811B (zh) | 2025-12-21 |
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