JP2023525758A5 - - Google Patents
Info
- Publication number
- JP2023525758A5 JP2023525758A5 JP2022567883A JP2022567883A JP2023525758A5 JP 2023525758 A5 JP2023525758 A5 JP 2023525758A5 JP 2022567883 A JP2022567883 A JP 2022567883A JP 2022567883 A JP2022567883 A JP 2022567883A JP 2023525758 A5 JP2023525758 A5 JP 2023525758A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- aryl
- heteroaryl
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063021797P | 2020-05-08 | 2020-05-08 | |
| US63/021,797 | 2020-05-08 | ||
| PCT/US2021/031372 WO2021226510A2 (en) | 2020-05-08 | 2021-05-07 | Akt3 modulators and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023525758A JP2023525758A (ja) | 2023-06-19 |
| JP2023525758A5 true JP2023525758A5 (https=) | 2024-05-16 |
Family
ID=78468492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022567883A Pending JP2023525758A (ja) | 2020-05-08 | 2021-05-07 | Ａｋｔ３モジュレーターおよびその使用方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230181563A1 (https=) |
| EP (1) | EP4146196A4 (https=) |
| JP (1) | JP2023525758A (https=) |
| KR (1) | KR20230019109A (https=) |
| CN (1) | CN115956078A (https=) |
| AU (1) | AU2021269065A1 (https=) |
| BR (1) | BR112022022327A2 (https=) |
| CA (1) | CA3182675A1 (https=) |
| IL (1) | IL297596A (https=) |
| MX (1) | MX2022014019A (https=) |
| PH (1) | PH12022553026A1 (https=) |
| WO (1) | WO2021226510A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023525757A (ja) * | 2020-05-08 | 2023-06-19 | ジョージアミューン・インコーポレイテッド | Ａｋｔ３モジュレーター |
| AU2021266786A1 (en) * | 2020-05-08 | 2022-12-15 | Georgiamune, Inc. | Akt3 modulators |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4993838B2 (ja) * | 2000-08-11 | 2012-08-08 | バーテックス ファーマシューティカルズ インコーポレイテッド | Ｐ３８のインヒビターとしてのピリジン誘導体 |
| ATE461179T1 (de) * | 2003-04-24 | 2010-04-15 | Merck Sharp & Dohme | Hemmer der akt aktivität |
| WO2008046085A2 (en) * | 2006-10-12 | 2008-04-17 | Supergen, Inc. | Quinoline derivatives for modulating dna methylation |
| AR064010A1 (es) * | 2006-12-06 | 2009-03-04 | Merck & Co Inc | Inhibidores de la actividad de la akt |
| US7939546B2 (en) * | 2007-10-12 | 2011-05-10 | Supergen, Inc. | Quinoline derivatives for modulating DNA methylation |
| US7790746B2 (en) * | 2007-10-12 | 2010-09-07 | Supergen, Inc. | Quinoline derivatives for modulating DNA methylation |
| GB201207722D0 (en) * | 2012-05-02 | 2012-06-13 | Bergenbio As | Method |
| US9707278B2 (en) * | 2014-04-17 | 2017-07-18 | Augusta University Research Institute, Inc. | Methods of modulating immune responses by modifying Akt3 bioactivity |
| US10292978B2 (en) * | 2016-01-15 | 2019-05-21 | Augusta University Research Institute, Inc. | Specific Akt3 inhibitor and uses thereof |
| US10342868B2 (en) * | 2016-01-15 | 2019-07-09 | Augusta University Research Institute, Inc. | Methods and compositions for inhibiting Akt3 |
| CN110366749A (zh) * | 2017-06-29 | 2019-10-22 | 惠普发展公司，有限责任合伙企业 | 可操作来具有充当主显示器的区域和充当辅显示器的区域的连续平面显示器 |
| MX2020002611A (es) * | 2017-09-07 | 2020-07-13 | Univ Res Inst Inc Augusta | Activador especifico de akt3 y usos del mismo. |
-
2021
- 2021-05-07 EP EP21800335.8A patent/EP4146196A4/en active Pending
- 2021-05-07 US US17/923,696 patent/US20230181563A1/en active Pending
- 2021-05-07 CN CN202180046157.6A patent/CN115956078A/zh active Pending
- 2021-05-07 KR KR1020227042831A patent/KR20230019109A/ko active Pending
- 2021-05-07 WO PCT/US2021/031372 patent/WO2021226510A2/en not_active Ceased
- 2021-05-07 AU AU2021269065A patent/AU2021269065A1/en active Pending
- 2021-05-07 PH PH1/2022/553026A patent/PH12022553026A1/en unknown
- 2021-05-07 MX MX2022014019A patent/MX2022014019A/es unknown
- 2021-05-07 CA CA3182675A patent/CA3182675A1/en active Pending
- 2021-05-07 BR BR112022022327A patent/BR112022022327A2/pt unknown
- 2021-05-07 IL IL297596A patent/IL297596A/en unknown
- 2021-05-07 JP JP2022567883A patent/JP2023525758A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2879677B1 (en) | Substituted pyrazolone compounds and methods of use | |
| EP2680886B1 (en) | Substituted quinoline compounds | |
| CN101959516B (zh) | 用以治疗癌症的包含喹喔啉PI3Kα抑制剂的组合治疗 | |
| Liu et al. | Autophagy, a double-edged sword in anti-angiogenesis therapy | |
| US8975282B2 (en) | Substituted pyrazolone compounds and methods of use | |
| JP2015520753A5 (https=) | ||
| JP6150813B2 (ja) | 増殖性疾患の治療方法 | |
| JP2023525758A5 (https=) | ||
| US20160287564A1 (en) | Methods of administering glutaminase inhibitors | |
| JP2015523397A (ja) | Ｃｄｋ４／６阻害剤およびｂ−ｒａｆ阻害剤の組合せ医薬 | |
| JP6858132B2 (ja) | 乳がん治療剤 | |
| TW202214243A (zh) | 西奧羅尼聯合免疫檢查點抑製劑在抗腫瘤治療中的應用 | |
| PH12019500615A1 (en) | 5-[2-(PYRIDIN-2-YLAMINO)-1,3-THIAZOL-5-YL]-2,3-DIHYDRO-1H-ISOINDOL-1-ONE DERIVATIVES AND THEIR USE AS DUAL INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE DELTA and GAMMA | |
| JP2019502671A (ja) | 小分子組成物を用いてヒト腫瘍細胞を非腫瘍形成性細胞に直接リプログラミングすることを誘導する方法 | |
| KR20230118854A (ko) | IRE1α 억제제 및 이의 용도 | |
| JP6367038B2 (ja) | 受容体の細胞内輸送制御による白血病治療のための新規医薬組成物 | |
| TW202014184A (zh) | 用於治療癌症之組合 | |
| RU2667644C2 (ru) | Противоопухолевое средство | |
| WO2021210636A1 (ja) | 乳がん治療剤 | |
| US20210179591A1 (en) | New compounds for use as a therapeutically active substance and in particular for use in the treatment of tumors | |
| TW202535405A (zh) | 用於藉由增強數類已核准藥物的作用以治療癌症之alc1抑制劑 | |
| JP2023539775A (ja) | 疾患、障害又は状態の処置のための細胞組成物及び使用方法 | |
| JP2022513375A5 (https=) | ||
| HK1208341B (en) | Substituted pyrazolone compounds and methods of use |