JP2023525297A - 幹細胞をドーパミン作動性前駆細胞に分化させるための方法 - Google Patents

幹細胞をドーパミン作動性前駆細胞に分化させるための方法 Download PDF

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JP2023525297A
JP2023525297A JP2022567835A JP2022567835A JP2023525297A JP 2023525297 A JP2023525297 A JP 2023525297A JP 2022567835 A JP2022567835 A JP 2022567835A JP 2022567835 A JP2022567835 A JP 2022567835A JP 2023525297 A JP2023525297 A JP 2023525297A
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signaling
cells
stem cells
activator
neurons
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ラース ヨハン エリクソン
ジャンナ ウラジミーロヴナ アレクセンコ
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JP2022567835A 2020-05-07 2021-05-07 幹細胞をドーパミン作動性前駆細胞に分化させるための方法 Pending JP2023525297A (ja)

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GB2006792.2 2020-05-07
GBGB2006792.2A GB202006792D0 (en) 2020-05-07 2020-05-07 Method and uses thereof
PCT/EP2021/062226 WO2021224496A1 (en) 2020-05-07 2021-05-07 Methods for differentiating stem cells into dopaminergic progenitor cells

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WO2022081501A1 (en) * 2020-10-12 2022-04-21 Research Development Foundation Methods for making and using differentiated neural cells
AU2022247250A1 (en) 2021-03-30 2023-11-09 Trailhead Biosystems Inc. Methods and compositions for generating oligodendrocyte progenitor cells
JP2025524856A (ja) * 2022-07-21 2025-08-01 トレイルヘッド バイオシステムズ インコーポレイテッド 神経前駆細胞からヒト中脳ドーパミン作動性ニューロンを作製するための方法および組成物
CN115521903B (zh) * 2022-09-30 2024-05-17 中国科学院生态环境研究中心 体外诱导人多能干细胞分化为多巴胺能神经元的方法
US12565639B2 (en) 2023-06-13 2026-03-03 Aspen Neuroscience, Inc. Methods for differentiating dopaminergic neurons from stem cells
CN119432743A (zh) * 2023-07-28 2025-02-14 士泽生物医药（苏州）有限公司 一种诱导干细胞分化为运动神经前体细胞和/或运动神经元的试剂盒及其应用
CN117660335A (zh) * 2023-12-14 2024-03-08 广州百康细胞生命科技有限公司 一种使用化学重编辑法将体细胞转化成免疫细胞的方法
CN117448270B (zh) * 2023-12-22 2024-07-26 上海元戊医学技术有限公司 一种高效诱导多能干细胞分化为中脑多巴胺能神经前体细胞的方法
WO2025162486A1 (en) * 2024-01-31 2025-08-07 Center For Excellence In Brain Science And Intelligence Technology, Chinese Academy Of Sciences An additive composition and a method for promoting differentiation into a10 precursors and/or a10 neurons
WO2025193168A1 (en) * 2024-03-14 2025-09-18 National University Of Singapore Method of generating midbrain dopamine progenitors and neurons from stem cells

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JP2018506559A (ja) * 2015-02-26 2018-03-08 ザ マクレーン ホスピタル コーポレーション パーキンソン病の処置または予防のための方法および組成物

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WO2010096496A2 (en) * 2009-02-17 2010-08-26 Memorial Sloan-Kettering Cancer Center Methods of neural conversion of human embryonic stem cells
CN101935635A (zh) * 2010-07-30 2011-01-05 中国人民解放军第二军医大学 人骨髓多能干细胞的体外扩增和向多巴胺能神经元定向分化的方法
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WO2013163228A1 (en) * 2012-04-24 2013-10-31 International Stem Cell Corporation Derivation of neural stem cells and dopaminergic neurons from human pluripotent stem cells
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US11767508B2 (en) * 2017-07-24 2023-09-26 Wisconsin Alumni Research Foundation Methods and culture substrates for controlled induction of biomimetic neural tissues comprising singular rosette structures

Patent Citations (2)

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WO2011130675A2 (en) * 2010-04-16 2011-10-20 The Mclean Hospital Corporation Dopaminergic neurons differentiated from pluripotent stem cells and uses of thereof
JP2018506559A (ja) * 2015-02-26 2018-03-08 ザ マクレーン ホスピタル コーポレーション パーキンソン病の処置または予防のための方法および組成物

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CN115968401A (zh) 2023-04-14
GB202006792D0 (en) 2020-06-24
US20230233617A1 (en) 2023-07-27
CA3182115A1 (en) 2021-11-11
EP4146796A1 (en) 2023-03-15

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