JP2023525297A5 - - Google Patents
Info
- Publication number
- JP2023525297A5 JP2023525297A5 JP2022567835A JP2022567835A JP2023525297A5 JP 2023525297 A5 JP2023525297 A5 JP 2023525297A5 JP 2022567835 A JP2022567835 A JP 2022567835A JP 2022567835 A JP2022567835 A JP 2022567835A JP 2023525297 A5 JP2023525297 A5 JP 2023525297A5
- Authority
- JP
- Japan
- Prior art keywords
- midbrain dopaminergic
- stem cells
- cell population
- progenitor cells
- retinoic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2006792.2 | 2020-05-07 | ||
| GBGB2006792.2A GB202006792D0 (en) | 2020-05-07 | 2020-05-07 | Method and uses thereof |
| PCT/EP2021/062226 WO2021224496A1 (en) | 2020-05-07 | 2021-05-07 | Methods for differentiating stem cells into dopaminergic progenitor cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023525297A JP2023525297A (ja) | 2023-06-15 |
| JP2023525297A5 true JP2023525297A5 (https=) | 2024-05-14 |
Family
ID=71134903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022567835A Pending JP2023525297A (ja) | 2020-05-07 | 2021-05-07 | 幹細胞をドーパミン作動性前駆細胞に分化させるための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230233617A1 (https=) |
| EP (1) | EP4146796A1 (https=) |
| JP (1) | JP2023525297A (https=) |
| CN (1) | CN115968401A (https=) |
| CA (1) | CA3182115A1 (https=) |
| GB (1) | GB202006792D0 (https=) |
| WO (1) | WO2021224496A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022081501A1 (en) * | 2020-10-12 | 2022-04-21 | Research Development Foundation | Methods for making and using differentiated neural cells |
| AU2022247250A1 (en) | 2021-03-30 | 2023-11-09 | Trailhead Biosystems Inc. | Methods and compositions for generating oligodendrocyte progenitor cells |
| JP2025524856A (ja) * | 2022-07-21 | 2025-08-01 | トレイルヘッド バイオシステムズ インコーポレイテッド | 神経前駆細胞からヒト中脳ドーパミン作動性ニューロンを作製するための方法および組成物 |
| CN115521903B (zh) * | 2022-09-30 | 2024-05-17 | 中国科学院生态环境研究中心 | 体外诱导人多能干细胞分化为多巴胺能神经元的方法 |
| US12565639B2 (en) | 2023-06-13 | 2026-03-03 | Aspen Neuroscience, Inc. | Methods for differentiating dopaminergic neurons from stem cells |
| CN119432743A (zh) * | 2023-07-28 | 2025-02-14 | 士泽生物医药（苏州）有限公司 | 一种诱导干细胞分化为运动神经前体细胞和/或运动神经元的试剂盒及其应用 |
| CN117660335A (zh) * | 2023-12-14 | 2024-03-08 | 广州百康细胞生命科技有限公司 | 一种使用化学重编辑法将体细胞转化成免疫细胞的方法 |
| CN117448270B (zh) * | 2023-12-22 | 2024-07-26 | 上海元戊医学技术有限公司 | 一种高效诱导多能干细胞分化为中脑多巴胺能神经前体细胞的方法 |
| WO2025162486A1 (en) * | 2024-01-31 | 2025-08-07 | Center For Excellence In Brain Science And Intelligence Technology, Chinese Academy Of Sciences | An additive composition and a method for promoting differentiation into a10 precursors and/or a10 neurons |
| WO2025193168A1 (en) * | 2024-03-14 | 2025-09-18 | National University Of Singapore | Method of generating midbrain dopamine progenitors and neurons from stem cells |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001088104A2 (en) * | 2000-05-17 | 2001-11-22 | Geron Corporation | Neural progenitor cell populations |
| WO2010096496A2 (en) * | 2009-02-17 | 2010-08-26 | Memorial Sloan-Kettering Cancer Center | Methods of neural conversion of human embryonic stem cells |
| WO2011130675A2 (en) * | 2010-04-16 | 2011-10-20 | The Mclean Hospital Corporation | Dopaminergic neurons differentiated from pluripotent stem cells and uses of thereof |
| CN101935635A (zh) * | 2010-07-30 | 2011-01-05 | 中国人民解放军第二军医大学 | 人骨髓多能干细胞的体外扩增和向多巴胺能神经元定向分化的方法 |
| EP3693455A1 (en) * | 2011-11-04 | 2020-08-12 | Memorial Sloan-Kettering Cancer Center | Midbrain dopamine (da) neurons for engraftment |
| WO2013163228A1 (en) * | 2012-04-24 | 2013-10-31 | International Stem Cell Corporation | Derivation of neural stem cells and dopaminergic neurons from human pluripotent stem cells |
| ES2939807T3 (es) * | 2014-03-21 | 2023-04-27 | Fujifilm Cellular Dynamics Inc | Producción de neuronas dopaminérgicas del mesencéfalo y métodos para su utilización |
| US20180243343A1 (en) * | 2015-02-26 | 2018-08-30 | The Mclean Hospital Corporation | Methods and compositions for the treatment or prevention of parkinson's disease |
| US11767508B2 (en) * | 2017-07-24 | 2023-09-26 | Wisconsin Alumni Research Foundation | Methods and culture substrates for controlled induction of biomimetic neural tissues comprising singular rosette structures |
-
2020
- 2020-05-07 GB GBGB2006792.2A patent/GB202006792D0/en not_active Ceased
-
2021
- 2021-05-07 CA CA3182115A patent/CA3182115A1/en active Pending
- 2021-05-07 JP JP2022567835A patent/JP2023525297A/ja active Pending
- 2021-05-07 EP EP21724671.9A patent/EP4146796A1/en active Pending
- 2021-05-07 US US17/923,265 patent/US20230233617A1/en active Pending
- 2021-05-07 CN CN202180044066.9A patent/CN115968401A/zh active Pending
- 2021-05-07 WO PCT/EP2021/062226 patent/WO2021224496A1/en not_active Ceased
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