JP2023525049A - ナチュラルキラー細胞を標的とするキメラ抗原受容体（ｃａｒ） - Google Patents

ナチュラルキラー細胞を標的とするキメラ抗原受容体（ｃａｒ） Download PDF

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JP2023525049A
JP2023525049A JP2022567529A JP2022567529A JP2023525049A JP 2023525049 A JP2023525049 A JP 2023525049A JP 2022567529 A JP2022567529 A JP 2022567529A JP 2022567529 A JP2022567529 A JP 2022567529A JP 2023525049 A JP2023525049 A JP 2023525049A
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car
cells
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cell
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ワーグナー，トール
カメニ，フロリアーヌ・ンガコ
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シアトル・チルドレンズ・ホスピタル・ドゥーイング／ビジネス／アズ・シアトル・チルドレンズ・リサーチ・インスティテュート
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JP2022567529A 2020-05-08 2021-05-07 ナチュラルキラー細胞を標的とするキメラ抗原受容体（ｃａｒ） Pending JP2023525049A (ja)

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US202063022149P 2020-05-08 2020-05-08
US63/022,149 2020-05-08
PCT/US2021/031421 WO2021226543A2 (en) 2020-05-08 2021-05-07 Chimeric antigen receptors (cars) targeting natural killer cells

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US (1) US20230348854A1 (enExample)
EP (1) EP4146703A4 (enExample)
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KR (1) KR20230010228A (enExample)
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Cited By (1)

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WO2025225645A1 (ja) * 2024-04-24 2025-10-30 第一三共株式会社 Ｎｋｇ２ａアゴニストを用いた免疫拒絶の回避方法

Families Citing this family (6)

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WO2021249462A1 (zh) * 2020-06-11 2021-12-16 南京北恒生物科技有限公司 表达nk抑制性分子的工程化免疫细胞及其用途
US11802866B2 (en) * 2021-07-08 2023-10-31 Medic Life Sciences Inc. High-throughput screening system for identification of novel drugs and drug targets
EP4569117A2 (en) * 2022-08-11 2025-06-18 The Trustees of The University of Pennsylvania Universal t cells and compositions and methods of use thereof
JP2025005236A (ja) * 2023-06-27 2025-01-16 国立大学法人 東京大学 タンパク質シンチレーター
WO2025168691A1 (en) * 2024-02-07 2025-08-14 Astrazeneca Ab Engineered cells expressing modified hla-e polypeptide
CN120647771A (zh) * 2024-03-15 2025-09-16 上海鑫湾生物科技有限公司 一种激活免疫细胞杀伤肿瘤细胞的融合蛋白及其重组病毒和用途

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JP2010515709A (ja) * 2007-01-11 2010-05-13 ノヴォ ノルディスク アクティーゼルスカブ 抗ｋｉｒ抗体、製剤、およびその使用
JP2011510047A (ja) * 2008-01-24 2011-03-31 ノボ・ノルデイスク・エー／エス ヒト化抗ヒトｎｋｇ２ａモノクローナル抗体
JP2014513948A (ja) * 2011-04-20 2014-06-19 ザ ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャライゼーション β２ミクログロブリン欠損細胞
JP2017537627A (ja) * 2014-12-05 2017-12-21 シティ・オブ・ホープＣｉｔｙ ｏｆ Ｈｏｐｅ Ｃｓ１標的化キメラ抗原レセプター改変ｔ細胞
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