JP2023524547A5 - - Google Patents
Info
- Publication number
- JP2023524547A5 JP2023524547A5 JP2022567355A JP2022567355A JP2023524547A5 JP 2023524547 A5 JP2023524547 A5 JP 2023524547A5 JP 2022567355 A JP2022567355 A JP 2022567355A JP 2022567355 A JP2022567355 A JP 2022567355A JP 2023524547 A5 JP2023524547 A5 JP 2023524547A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- compound represented
- structural formula
- following structural
- methylcyclopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024173464A JP7643632B2 (ja) | 2020-05-07 | 2024-10-02 | Ｋｄｍ５阻害作用を有する３－アザビシクロ（３．１．０）ヘキサン誘導体およびその医薬用途 |
| JP2025029239A JP2025081677A (ja) | 2020-05-07 | 2025-02-26 | Ｋｄｍ５阻害作用を有する３－アザビシクロ（３．１．０）ヘキサン誘導体およびその医薬用途 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2020/088925 | 2020-05-07 | ||
| CN2020088925 | 2020-05-07 | ||
| PCT/CN2021/091843 WO2021223699A1 (en) | 2020-05-07 | 2021-05-06 | 3-azabicyclo(3.1.0)hexane derivatives having kdm5 inhibitory activity and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024173464A Division JP7643632B2 (ja) | 2020-05-07 | 2024-10-02 | Ｋｄｍ５阻害作用を有する３－アザビシクロ（３．１．０）ヘキサン誘導体およびその医薬用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023524547A JP2023524547A (ja) | 2023-06-12 |
| JP2023524547A5 true JP2023524547A5 (https=) | 2024-04-17 |
| JP7643466B2 JP7643466B2 (ja) | 2025-03-11 |
Family
ID=76159223
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022567355A Active JP7643466B2 (ja) | 2020-05-07 | 2021-05-06 | Ｋｄｍ５阻害作用を有する３－アザビシクロ（３．１．０）ヘキサン誘導体およびその医薬用途 |
| JP2024173464A Active JP7643632B2 (ja) | 2020-05-07 | 2024-10-02 | Ｋｄｍ５阻害作用を有する３－アザビシクロ（３．１．０）ヘキサン誘導体およびその医薬用途 |
| JP2025029239A Withdrawn JP2025081677A (ja) | 2020-05-07 | 2025-02-26 | Ｋｄｍ５阻害作用を有する３－アザビシクロ（３．１．０）ヘキサン誘導体およびその医薬用途 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024173464A Active JP7643632B2 (ja) | 2020-05-07 | 2024-10-02 | Ｋｄｍ５阻害作用を有する３－アザビシクロ（３．１．０）ヘキサン誘導体およびその医薬用途 |
| JP2025029239A Withdrawn JP2025081677A (ja) | 2020-05-07 | 2025-02-26 | Ｋｄｍ５阻害作用を有する３－アザビシクロ（３．１．０）ヘキサン誘導体およびその医薬用途 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11691968B2 (https=) |
| EP (2) | EP4471027A1 (https=) |
| JP (3) | JP7643466B2 (https=) |
| KR (2) | KR20260046494A (https=) |
| CN (1) | CN115461338B (https=) |
| AU (1) | AU2021268223B2 (https=) |
| BR (1) | BR112022022005A2 (https=) |
| CA (1) | CA3181604A1 (https=) |
| ES (1) | ES3037418T3 (https=) |
| IL (1) | IL297900B2 (https=) |
| MX (1) | MX2022013692A (https=) |
| NZ (1) | NZ793960A (https=) |
| TW (1) | TWI895412B (https=) |
| WO (1) | WO2021223699A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3999183A4 (en) * | 2019-07-17 | 2023-11-15 | Ono Pharmaceutical Co., Ltd. | COMPOUNDS HAVING KDM5 INHIBITANT ACTION AND THEIR PHARMACEUTICAL USES |
| ES3037418T3 (en) | 2020-05-07 | 2025-10-01 | Ono Pharmaceutical Co | 3-azabicyclo(3.1.0)hexane derivatives having kdm5 inhibitory activity and use thereof |
| JP7743829B2 (ja) * | 2021-11-05 | 2025-09-25 | 小野薬品工業株式会社 | Ｋｄｍ５阻害作用を有する化合物を含有する医薬組成物 |
| WO2025239445A1 (ja) * | 2024-05-17 | 2025-11-20 | 小野薬品工業株式会社 | 認知症の行動および心理症状の予防、進行抑制および／または治療剤 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI244481B (en) * | 1998-12-23 | 2005-12-01 | Pfizer | 3-azabicyclo[3.1.0]hexane derivatives useful in therapy |
| GB0311859D0 (en) | 2003-05-22 | 2003-06-25 | Merck Sharp & Dohme | Therapeutic agents |
| JP5017103B2 (ja) | 2004-06-17 | 2012-09-05 | トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド | 薬剤共結晶組成物および関連した使用方法 |
| JP2008524331A (ja) | 2004-12-21 | 2008-07-10 | 武田薬品工業株式会社 | ジペプチジルペプチダーゼ阻害剤 |
| RU2487127C2 (ru) | 2007-10-09 | 2013-07-10 | Ф.Хоффманн-Ля Рош Аг | Хиральные цис-имидазолины |
| CN107912040B (zh) * | 2014-10-10 | 2021-04-06 | 基因泰克公司 | 作为组蛋白脱甲基酶抑制剂的吡咯烷酰胺化合物 |
| CN108341819B (zh) | 2017-01-22 | 2021-06-15 | 南京药捷安康生物科技有限公司 | 磷酸二酯酶抑制剂及其用途 |
| EP3999183A4 (en) | 2019-07-17 | 2023-11-15 | Ono Pharmaceutical Co., Ltd. | COMPOUNDS HAVING KDM5 INHIBITANT ACTION AND THEIR PHARMACEUTICAL USES |
| ES3037418T3 (en) | 2020-05-07 | 2025-10-01 | Ono Pharmaceutical Co | 3-azabicyclo(3.1.0)hexane derivatives having kdm5 inhibitory activity and use thereof |
-
2021
- 2021-05-06 ES ES21728166T patent/ES3037418T3/es active Active
- 2021-05-06 MX MX2022013692A patent/MX2022013692A/es unknown
- 2021-05-06 KR KR1020267006670A patent/KR20260046494A/ko active Pending
- 2021-05-06 CA CA3181604A patent/CA3181604A1/en active Pending
- 2021-05-06 AU AU2021268223A patent/AU2021268223B2/en active Active
- 2021-05-06 CN CN202180032139.2A patent/CN115461338B/zh active Active
- 2021-05-06 NZ NZ793960A patent/NZ793960A/en unknown
- 2021-05-06 EP EP24182835.9A patent/EP4471027A1/en active Pending
- 2021-05-06 KR KR1020227037880A patent/KR102937044B1/ko active Active
- 2021-05-06 BR BR112022022005A patent/BR112022022005A2/pt unknown
- 2021-05-06 TW TW110116409A patent/TWI895412B/zh active
- 2021-05-06 WO PCT/CN2021/091843 patent/WO2021223699A1/en not_active Ceased
- 2021-05-06 EP EP21728166.6A patent/EP4146645B1/en active Active
- 2021-05-06 JP JP2022567355A patent/JP7643466B2/ja active Active
- 2021-05-06 IL IL297900A patent/IL297900B2/en unknown
-
2022
- 2022-10-24 US US17/971,844 patent/US11691968B2/en active Active
-
2023
- 2023-05-05 US US18/144,030 patent/US12269817B2/en active Active
-
2024
- 2024-10-02 JP JP2024173464A patent/JP7643632B2/ja active Active
-
2025
- 2025-02-26 JP JP2025029239A patent/JP2025081677A/ja not_active Withdrawn
- 2025-02-28 US US19/067,084 patent/US20250214984A1/en active Pending