JP2023524532A - 腫瘍治療電場を発生させる導電性パッド、その生産および使用の方法 - Google Patents

腫瘍治療電場を発生させる導電性パッド、その生産および使用の方法 Download PDF

Info

Publication number
JP2023524532A
JP2023524532A JP2022567156A JP2022567156A JP2023524532A JP 2023524532 A JP2023524532 A JP 2023524532A JP 2022567156 A JP2022567156 A JP 2022567156A JP 2022567156 A JP2022567156 A JP 2022567156A JP 2023524532 A JP2023524532 A JP 2023524532A
Authority
JP
Japan
Prior art keywords
conductive
layer
gel
pad
conductive gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022567156A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023524532A5 (https=
Inventor
リチャード・デスローリアーズ
Original Assignee
ノボキュア ゲーエムベーハー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノボキュア ゲーエムベーハー filed Critical ノボキュア ゲーエムベーハー
Publication of JP2023524532A publication Critical patent/JP2023524532A/ja
Publication of JP2023524532A5 publication Critical patent/JP2023524532A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0492—Patch electrodes
    • A61N1/0496—Patch electrodes characterised by using specific chemical compositions, e.g. hydrogel compositions, adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0484—Garment electrodes worn by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0492—Patch electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/06—Electrodes for high-frequency therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002—Cancer treatment, e.g. tumour
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022567156A 2020-05-06 2021-05-06 腫瘍治療電場を発生させる導電性パッド、その生産および使用の方法 Pending JP2023524532A (ja)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US202063020636P 2020-05-06 2020-05-06
US63/020,636 2020-05-06
US202063030138P 2020-05-26 2020-05-26
US63/030,138 2020-05-26
US202063046364P 2020-06-30 2020-06-30
US63/046,364 2020-06-30
US202063061419P 2020-08-05 2020-08-05
US202063061316P 2020-08-05 2020-08-05
US63/061,419 2020-08-05
US63/061,316 2020-08-05
US202063068213P 2020-08-20 2020-08-20
US63/068,213 2020-08-20
US202063085476P 2020-09-30 2020-09-30
US63/085,476 2020-09-30
US202063128276P 2020-12-21 2020-12-21
US63/128,276 2020-12-21
US202163141315P 2021-01-25 2021-01-25
US63/141,315 2021-01-25
PCT/US2021/031119 WO2021226353A1 (en) 2020-05-06 2021-05-06 Conductive pad generating tumor treating field and methods of production and use thereof

Publications (2)

Publication Number Publication Date
JP2023524532A true JP2023524532A (ja) 2023-06-12
JP2023524532A5 JP2023524532A5 (https=) 2024-05-15

Family

ID=76197593

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022567156A Pending JP2023524532A (ja) 2020-05-06 2021-05-06 腫瘍治療電場を発生させる導電性パッド、その生産および使用の方法

Country Status (6)

Country Link
US (9) US20210346693A1 (https=)
EP (1) EP4146326A1 (https=)
JP (1) JP2023524532A (https=)
CN (1) CN116367881A (https=)
TW (2) TW202537657A (https=)
WO (1) WO2021226353A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024144709A (ja) * 2016-06-30 2024-10-11 ノボキュア ゲーエムベーハー 身体への腫瘍治療電場の長手方向伝達用のアレイ
WO2025114837A1 (en) * 2023-11-30 2025-06-05 Solventum Intellectual Properties Company Article for securement to skin and method of use thereof

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3178883A1 (en) * 2020-06-30 2022-01-06 Novocure Gmbh Flexible transducer arrays with a polymer insulating layer for applying tumor treating fields (ttfields)
US20240269473A1 (en) * 2021-06-25 2024-08-15 Northwestern University Bioresorbable cardiovascular instruments, and operation and fabrication methods of same
KR20240027008A (ko) * 2021-06-30 2024-02-29 노보큐어 게엠베하 종양 치료 필드(ttfield)를 인가하기 위한 트랜스듀서 어레이에서 전류를 제한하기 위한 커패시터의 사용
IT202100022166A1 (it) * 2021-08-23 2023-02-23 Led S P A Elettrodo neutro flessibile per la radiofrequenza chirurgica e fisioterapica e kit associato
WO2023042080A1 (en) 2021-09-14 2023-03-23 Novocure Gmbh Temperature independent method and system for applying ttfields
JP2024533808A (ja) 2021-09-30 2024-09-12 ノボキュア ゲーエムベーハー 毛包と相互作用する腫瘍治療電場を印加するための方法およびシステム
CN114162821B (zh) * 2021-12-08 2023-04-25 中国地质大学（北京） 肖特基结复合材料及其制备方法和应用
WO2023105468A1 (en) 2021-12-10 2023-06-15 Novocure Gmbh Compression garment assembly for applying ttfields and methods of production and use thereof
US12434051B2 (en) 2021-12-10 2025-10-07 Novocure Gmbh Compression garment assembly for applying TTFields and methods of production and use thereof
US12599765B2 (en) 2021-12-14 2026-04-14 Novocure Gmbh Shifting of transducer array to reduce skin irritation
KR20240118094A (ko) * 2021-12-17 2024-08-02 노보큐어 게엠베하 전극 어레이의 도전성 접착층 제거 및 교체를 위한 시스템 및 방법
CN114225215B (zh) * 2021-12-31 2023-05-05 湖南安泰康成生物科技有限公司 电极系统
CA3253015A1 (en) * 2022-02-25 2023-08-31 Hubbell Incorporated EXOTHORMIC REACTION METAL WELDING ASSEMBLIES AND METHODS OF USE
US20250170395A1 (en) * 2022-02-28 2025-05-29 Rhode Island Hospital Hydrogel conductivity impacts skin dose from tumor treating fields
KR102726242B1 (ko) * 2022-04-11 2024-11-04 가천대학교 산학협력단 경두개 직류자극술(tDCS)용 전극
US20240001134A1 (en) * 2022-06-30 2024-01-04 Novocure Gmbh Adhesive layer with protective border for use in a tumor treating fields transducer
WO2024052877A1 (en) 2022-09-08 2024-03-14 Novocure Gmbh Constructing a 3d phantom with a matrix material having conductive particles dispersed therein
JP2025536117A (ja) 2022-09-27 2025-10-31 ノボキュア ゲーエムベーハー 内部ｔｔ場強度を測定するための摂取可能な植え込め型デバイス
CA3180284A1 (en) 2022-09-29 2024-03-29 Novocure Gmbh Transducer array having a temperature sensor isolation layer between a temperature sensor and external environment
US20240173544A1 (en) 2022-11-30 2024-05-30 Novocure Gmbh Transducer arrays having alternative array materials
JP2026502050A (ja) * 2022-12-28 2026-01-21 ノボキュア ゲーエムベーハー 一体型腫瘍治療電界電圧発生器を有する着用可能な衣服
US12268863B2 (en) 2023-02-06 2025-04-08 Novocure Gmbh Shiftable transducer array with anisotropic material layer
WO2024201412A1 (en) 2023-03-31 2024-10-03 Novocure Gmbh Microneedles to overcome contact resistance
WO2024254086A2 (en) * 2023-06-05 2024-12-12 New York University A distributed system for biosensing
CN121969417A (zh) 2023-09-28 2026-05-01 诺沃库勒有限责任公司 具有子阵列的换能器阵列及其生产和使用方法
CN121941528A (zh) 2023-09-29 2026-04-28 诺沃库勒有限责任公司 将换能器阵列重新施加到患者的设备和方法
WO2025068877A1 (en) 2023-09-29 2025-04-03 Novocure Gmbh Low frequency rf ablation system
SE2450263A1 (en) * 2024-03-07 2025-09-08 Force Oncology Ab Personalized electrodes
WO2025202989A1 (en) * 2024-03-29 2025-10-02 Novocure Gmbh Applying alternating electric fields to a subjects body in multiple directions, with certain directions being prioritized
CN118384408B (zh) * 2024-06-28 2024-08-30 成都德而塔生物科技有限公司 一种防干扰的超声组合式贴片及超声治疗头
CN119792806B (zh) * 2025-02-26 2025-08-29 江苏海莱新创医疗科技有限公司 肿瘤电场治疗系统

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002501804A (ja) * 1998-02-09 2002-01-22 アクセルガード・マニュファクチュアリング・カンパニー・リミテッド 医療用電極及び製造方法
JP2004510481A (ja) * 2000-10-02 2004-04-08 アクセルガード・マニュファクチュアリング・カンパニー・リミテッド 浮動電極
JP2006513739A (ja) * 2002-10-02 2006-04-27 スタンデン・リミテッド 腫瘍等を治療するための装置ならびに腫瘍の治療のための装置を備えた製品
US20090002067A1 (en) * 2007-06-27 2009-01-01 Healthonics, Inc Method and System for Signal Coupling and Direct Current Blocking
KR20100028761A (ko) * 2008-09-05 2010-03-15 표대영 고주파 치료 장치용 전극 유닛 및 이를 포함한 고주파 치료장치
CN103585715A (zh) * 2013-11-22 2014-02-19 清华大学 一种集成中频电流电场刺激设备
CN110180082A (zh) * 2019-07-01 2019-08-30 深圳明医医疗科技有限公司 中频治疗贴和中频治疗系统
JP2019524206A (ja) * 2016-06-30 2019-09-05 ノヴォキュア・リミテッド 身体への腫瘍治療電場の長手方向伝達用のアレイ
WO2020070914A1 (ja) * 2018-10-01 2020-04-09 亮嗣 桑畑 生体刺激装置

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4437464A (en) * 1981-11-09 1984-03-20 C.R. Bard, Inc. Electrosurgical generator safety apparatus
FR2678094B1 (fr) 1991-06-20 1993-10-08 France Telecom Carte a memoire de comptage de donnees et appareil de lecture.
ATE159179T1 (de) 1992-06-02 1997-11-15 Alza Corp Vorrichtung zur iontophoretischen verabreichung von medikamenten
US5974344A (en) 1998-03-02 1999-10-26 Shoemaker, Ii; Charles Wound care electrode
US6493588B1 (en) * 1998-03-18 2002-12-10 Mmc/Gatx Partnership No. 1 Electro-nerve stimulator systems and methods
US6347246B1 (en) 2000-02-03 2002-02-12 Axelgaard Manufacturing Company, Ltd. Electrotransport adhesive for iontophoresis device
US7599746B2 (en) 2000-02-17 2009-10-06 Standen Ltd Apparatus and method for preventing the spread of cancerous metastases and for elimination of metastases
US7146210B2 (en) * 2000-02-17 2006-12-05 Standen Ltd. Apparatus and method for optimizing tumor treatment efficiency by electric fields
US7016725B2 (en) 2001-11-06 2006-03-21 Standen Ltd. Method and apparatus for destroying dividing cells
US7089054B2 (en) 2002-10-02 2006-08-08 Standen Ltd. Apparatus and method for treating a tumor or the like
CN1416466A (zh) 2000-02-17 2003-05-07 约朗姆·帕尔蒂 破坏正在分裂的细胞的方法和装置
US7805201B2 (en) 2000-02-17 2010-09-28 Standen Ltd. Treating a tumor or the like with an electric field
US8313908B2 (en) 2000-02-23 2012-11-20 The Trustees Of The University Of Pennsylvania Regulation of stem cell gene production with specific and selective electric and electromagnetic fields
EP1235615B1 (en) 2000-08-24 2006-02-15 Unomedical Limited Biomedical electrodes and biomedical electrodes for electrostimulation
US20030153964A1 (en) 2001-05-01 2003-08-14 Polybiomed Limited Polymerizable material and sheet material derived therefrom
US7171276B2 (en) 2001-06-29 2007-01-30 Abbott Laboratories Hydrogel and scrim assembly for use with electro-acupuncture device with stimulation electrodes
JP4110527B2 (ja) * 2003-05-06 2008-07-02 日本光電工業株式会社 医療用電極
WO2008032282A2 (en) 2006-09-13 2008-03-20 Compex Medical S.A. Electrode set and stimulating device
EP2183024B1 (en) 2007-08-14 2019-05-15 Novocure Ltd. Treating parasites with electric fields
US8715203B2 (en) * 2007-09-17 2014-05-06 Novocure Limited Composite electrode
WO2010056771A1 (en) * 2008-11-11 2010-05-20 Shifamed Llc Low profile electrode assembly
US8965534B2 (en) * 2012-09-13 2015-02-24 Covidien Lp Apparatus and method for energy distribution in a medical electrode
AU2014207265B2 (en) * 2013-01-21 2017-04-20 Cala Health, Inc. Devices and methods for controlling tremor
JP6134865B2 (ja) * 2013-09-16 2017-05-24 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 生物医学的電極パッド
AU2015271774B2 (en) * 2014-06-02 2020-04-16 Cala Health, Inc. Systems and methods for peripheral nerve stimulation to treat tremor
US10258788B2 (en) 2015-01-05 2019-04-16 Thync Global, Inc. Electrodes having surface exclusions
EP3067073A1 (en) * 2015-03-09 2016-09-14 Centre National De La Recherche Scientifique Method of forming a medical device comprising graphene
CN107580516A (zh) 2015-05-08 2018-01-12 皇家飞利浦有限公司 湿/干可转换电极以及其使用方法
HK1246713A1 (zh) * 2015-05-29 2018-09-14 赛威医疗公司 用於经皮电刺激的方法和装置
DE102015012381A1 (de) * 2015-09-21 2017-03-23 Leonhard Lang Hydrogel, Herstellungsverfahren und medizinisches Gerät umfassend eine damit beschichtete Elektrode
US10188851B2 (en) 2015-10-28 2019-01-29 Novocure Limited TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements
GB201608691D0 (en) 2016-05-17 2016-06-29 Univ Southampton Electrode
WO2018003787A1 (ja) * 2016-06-27 2018-01-04 積水化成品工業株式会社 ゲルシート
WO2018081423A1 (en) * 2016-10-26 2018-05-03 Elira, Inc. Systems and methods for using a transcutaneous electrical stimulation device to deliver titrated therapy
WO2018109691A2 (en) 2016-12-13 2018-06-21 Zeev Bomzon Treating patients with ttfields with the electrode positions optimized using deformable templates
JP7228903B2 (ja) 2017-12-22 2023-02-27 国立大学法人東北大学 電極体、電極体の製造方法
US11058886B1 (en) * 2018-04-05 2021-07-13 Evanesc Therapeutics, Inc. Method of polarization control of evanescent waves for treating tumors
JP7139448B2 (ja) 2018-04-09 2022-09-20 ノボキュア ゲーエムベーハー ＴＴＦｉｅｌｄｓ及びオーロラキナーゼ阻害剤による腫瘍の治療
PL3775956T3 (pl) 2018-04-10 2022-10-10 Novocure Gmbh Szacunki przewodności ac o niskiej częstotliwości (< 1 mhz) pozyskane z dwóch obrazów mri o różnych czasach repetycji
US20190314638A1 (en) * 2018-04-17 2019-10-17 Inmode Ltd. Rf device for skin and fat treatment
WO2019209969A1 (en) 2018-04-24 2019-10-31 Thync Global, Inc. Streamlined and pre-set neuromodulators
US12274562B2 (en) * 2018-06-15 2025-04-15 Otsuka Pharmaceutical Co. Ltd. Re-wearable physiological monitoring device
WO2020069308A1 (en) * 2018-09-28 2020-04-02 Zoll Medical Corporation Adhesively coupled wearable medical device
KR102380202B1 (ko) * 2018-12-13 2022-03-30 주식회사 바른바이오 자극 장치
GB2584278B (en) * 2019-05-23 2024-02-14 Ablatus Therapeutics Ltd Conductive member for use in radiofrequency ablation

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002501804A (ja) * 1998-02-09 2002-01-22 アクセルガード・マニュファクチュアリング・カンパニー・リミテッド 医療用電極及び製造方法
JP2004510481A (ja) * 2000-10-02 2004-04-08 アクセルガード・マニュファクチュアリング・カンパニー・リミテッド 浮動電極
JP2006513739A (ja) * 2002-10-02 2006-04-27 スタンデン・リミテッド 腫瘍等を治療するための装置ならびに腫瘍の治療のための装置を備えた製品
US20090002067A1 (en) * 2007-06-27 2009-01-01 Healthonics, Inc Method and System for Signal Coupling and Direct Current Blocking
JP2010532644A (ja) * 2007-06-27 2010-10-07 メドレリーフ インコーポレーテッド 信号結合及び直流阻止のための方法及びシステム
KR20100028761A (ko) * 2008-09-05 2010-03-15 표대영 고주파 치료 장치용 전극 유닛 및 이를 포함한 고주파 치료장치
CN103585715A (zh) * 2013-11-22 2014-02-19 清华大学 一种集成中频电流电场刺激设备
JP2019524206A (ja) * 2016-06-30 2019-09-05 ノヴォキュア・リミテッド 身体への腫瘍治療電場の長手方向伝達用のアレイ
WO2020070914A1 (ja) * 2018-10-01 2020-04-09 亮嗣 桑畑 生体刺激装置
CN110180082A (zh) * 2019-07-01 2019-08-30 深圳明医医疗科技有限公司 中频治疗贴和中频治疗系统

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024144709A (ja) * 2016-06-30 2024-10-11 ノボキュア ゲーエムベーハー 身体への腫瘍治療電場の長手方向伝達用のアレイ
WO2025114837A1 (en) * 2023-11-30 2025-06-05 Solventum Intellectual Properties Company Article for securement to skin and method of use thereof

Also Published As

Publication number Publication date
US12472353B2 (en) 2025-11-18
US12465760B2 (en) 2025-11-11
US20240157135A1 (en) 2024-05-16
US20240157132A1 (en) 2024-05-16
US20240157131A1 (en) 2024-05-16
US12440671B2 (en) 2025-10-14
US20240165406A1 (en) 2024-05-23
US12427308B2 (en) 2025-09-30
US12434052B2 (en) 2025-10-07
US20240157136A1 (en) 2024-05-16
EP4146326A1 (en) 2023-03-15
TWI889816B (zh) 2025-07-11
US20210346693A1 (en) 2021-11-11
CN116367881A (zh) 2023-06-30
TW202537657A (zh) 2025-10-01
WO2021226353A1 (en) 2021-11-11
US12569677B2 (en) 2026-03-10
US20240157133A1 (en) 2024-05-16
US20240165405A1 (en) 2024-05-23
TW202200232A (zh) 2022-01-01
US20240157134A1 (en) 2024-05-16
US12420089B2 (en) 2025-09-23

Similar Documents

Publication Publication Date Title
US12465760B2 (en) Pad generating tumor treating field and having kirigami-like cuts
TWI864225B (zh) 用於ｔｔｆｉｅｌｄ生成系統之組件及換能器陣列
US11534601B2 (en) Perforated hydrogel configurations and methods of production and use thereof
TW202241543A (zh) 電極陣列及其製造與使用方法
BR112020025399B1 (pt) Dispositivo para aumentar a absorção de substâncias através da pele de um animal ou humano
EP4344413B1 (en) Conductive pad generating tumor treating field
US20260091226A1 (en) Transducer array generating tumor treating field and methods of production and use thereof
HK40122387A (en) Conductive pad generating tumor treating field and methods of production and use thereof
JP2024533808A (ja) 毛包と相互作用する腫瘍治療電場を印加するための方法およびシステム
HK40103097A (en) Conductive pad generating tumor treating field
HK40103097B (en) Conductive pad generating tumor treating field
WO2025205761A1 (ja) 薬物送達装置、及び薬物送達装置の製造方法
CN117042835A (zh) 电极阵列及其生产和使用的方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240501

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20240501

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20250214

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250218

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20250508

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250818

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20251118

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20260205