PL3775956T3 - Szacunki przewodności ac o niskiej częstotliwości (< 1 mhz) pozyskane z dwóch obrazów mri o różnych czasach repetycji - Google Patents
Szacunki przewodności ac o niskiej częstotliwości (< 1 mhz) pozyskane z dwóch obrazów mri o różnych czasach repetycjiInfo
- Publication number
- PL3775956T3 PL3775956T3 PL19725401.4T PL19725401T PL3775956T3 PL 3775956 T3 PL3775956 T3 PL 3775956T3 PL 19725401 T PL19725401 T PL 19725401T PL 3775956 T3 PL3775956 T3 PL 3775956T3
- Authority
- PL
- Poland
- Prior art keywords
- estimates
- mhz
- conductivity
- low frequency
- mri images
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
- A61B5/0036—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room including treatment, e.g., using an implantable medical device, ablating, ventilating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
- A61B5/004—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
- A61B5/0042—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/4808—Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5602—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by filtering or weighting based on different relaxation times within the sample, e.g. T1 weighting using an inversion pulse
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5607—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reducing the NMR signal of a particular spin species, e.g. of a chemical species for fat suppression, or of a moving spin species for black-blood imaging
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5608—Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2576/00—Medical imaging apparatus involving image processing or analysis
- A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
- A61B2576/026—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part for the brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36031—Control systems using physiological parameters for adjustment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/58—Calibration of imaging systems, e.g. using test probes, Phantoms; Calibration objects or fiducial markers such as active or passive RF coils surrounding an MR active material
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Radiology & Medical Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- High Energy & Nuclear Physics (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Signal Processing (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Theoretical Computer Science (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Artificial Intelligence (AREA)
- Physiology (AREA)
- Child & Adolescent Psychology (AREA)
- Developmental Disabilities (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Social Psychology (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862655670P | 2018-04-10 | 2018-04-10 | |
| PCT/IB2019/052931 WO2019197999A1 (en) | 2018-04-10 | 2019-04-09 | Low frequency (<1 mhz) ac conductivity estimates derived from two mri images having different repetition times |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3775956T3 true PL3775956T3 (pl) | 2022-10-10 |
Family
ID=66625212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19725401.4T PL3775956T3 (pl) | 2018-04-10 | 2019-04-09 | Szacunki przewodności ac o niskiej częstotliwości (< 1 mhz) pozyskane z dwóch obrazów mri o różnych czasach repetycji |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11650277B2 (pl) |
| EP (2) | EP3832335A1 (pl) |
| JP (1) | JP7225373B2 (pl) |
| KR (1) | KR102687814B1 (pl) |
| CN (1) | CN112424626B (pl) |
| CA (1) | CA3096429C (pl) |
| PL (1) | PL3775956T3 (pl) |
| WO (1) | WO2019197999A1 (pl) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
| US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
| US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
| AU2017289870B2 (en) | 2016-06-30 | 2021-12-23 | Novocure Gmbh | Arrays for longitudinal delivery of TTFields to a body |
| WO2018134733A1 (en) | 2017-01-19 | 2018-07-26 | Moshe Giladi | System for viewing cell cultures under a microscope whilst applying ttfields |
| PL3775956T3 (pl) | 2018-04-10 | 2022-10-10 | Novocure Gmbh | Szacunki przewodności ac o niskiej częstotliwości (< 1 mhz) pozyskane z dwóch obrazów mri o różnych czasach repetycji |
| CN116603165A (zh) | 2018-07-03 | 2023-08-18 | 斯坦福大学托管董事会 | 使用交变电场提高细胞膜通透性 |
| CA3103070C (en) | 2018-07-10 | 2024-01-09 | Novocure Gmbh | Inhibiting viral infection using alternating electric fields |
| US11179322B2 (en) | 2018-07-10 | 2021-11-23 | Novocure Gmbh | Methods and compositions for treating tumors with TTFields and sorafenib |
| MX2020013431A (es) | 2018-07-18 | 2021-05-27 | Novocure Gmbh | Uso de densidad de perdida de potencia y mediciones relacionadas para cuantificar la dosis de campos de tratamiento de tumores (ttfield). |
| KR20250069692A (ko) | 2018-08-23 | 2025-05-19 | 카스텐 하게만 | 뇌-혈액 장벽 투과성을 향상시키기 위한 교번 전기장의 이용 |
| CN112770806B (zh) | 2018-09-07 | 2025-12-05 | 诺沃库勒有限责任公司 | 使用交变电场治疗自身免疫性疾病以减少t细胞的增殖 |
| US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
| CN118925056A (zh) | 2018-10-15 | 2024-11-12 | 诺沃库勒有限责任公司 | 生成遍及大脑具有高均匀性的肿瘤治疗场(ttfields) |
| US11369790B2 (en) | 2018-10-25 | 2022-06-28 | Novocure Gmbh | Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy |
| KR102747887B1 (ko) | 2018-11-19 | 2024-12-27 | 노보큐어 게엠베하 | 선택적으로 주소 지정 가능한 하위 요소를 하지는 종양 치료장 제공을 위한 어레이 |
| SG11202101810SA (en) | 2018-11-29 | 2021-03-30 | Novocure Gmbh | Enhanced-flexibility transducer arrays for delivering ttfields (tumor treating fields) |
| CN113330485B (zh) | 2019-01-08 | 2025-09-26 | 诺沃库勒有限责任公司 | 评估将图像分割成不同类型组织的质量,用于使用肿瘤治疗场(TTField)来计划治疗 |
| US11554262B2 (en) | 2019-02-26 | 2023-01-17 | Novocure Gmbh | Determining a frequency for TTFields treatment based on an electrical characteristic of targeted cancer cells |
| EP3954314B1 (en) | 2019-02-27 | 2025-01-08 | Novocure GmbH | Delivering tumor treating fields (ttfields) using implantable transducer arrays |
| EP3988099B1 (en) | 2019-03-29 | 2023-06-07 | Novocure GmbH | Methods for restoring sensitivity to ttfields in ttfields-resistant cancer cells with ptger3 inhibitors |
| EP3924039B1 (en) | 2019-04-17 | 2023-11-22 | Novocure GmbH | Uploading data from an isolated system without compromising isolation |
| CN114364432B (zh) | 2019-07-31 | 2025-10-31 | 诺沃库勒有限责任公司 | 经由埋入颅骨植入物中的电极施加肿瘤治疗场(TTField) |
| US12343336B2 (en) | 2019-08-05 | 2025-07-01 | Novocure Gmbh | Increasing cancer cells' sensitivity to tumor treating fields (TTFields) by inhibiting IL11 activity |
| US11890467B2 (en) | 2019-08-30 | 2024-02-06 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the neck |
| US11534601B2 (en) | 2019-11-08 | 2022-12-27 | Novocure Gmbh | Perforated hydrogel configurations and methods of production and use thereof |
| WO2021111186A1 (en) | 2019-12-02 | 2021-06-10 | Novocure Gmbh | Methods and apparatuses for optimizing transducer array placement |
| US12121739B2 (en) | 2019-12-31 | 2024-10-22 | Novocure Gmbh | Methods, systems, and apparatuses for managing temperatures induced by alternating fields |
| CA3163315A1 (en) | 2019-12-31 | 2021-07-08 | Novocure Gmbh | High voltage, high efficiency sine wave generator that prevents spikes during amplitude adjustments and switching of channels |
| CN114830248A (zh) | 2019-12-31 | 2022-07-29 | 诺沃库勒有限责任公司 | 用于电场分布的快速近似的方法、系统和装置 |
| TWI902740B (zh) | 2019-12-31 | 2025-11-01 | 瑞士商諾沃庫勒有限責任公司 | 用於影像分割之方法、系統和設備 |
| DK4074367T3 (da) | 2019-12-31 | 2023-05-22 | Novocure Gmbh | Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer |
| CA3168285A1 (en) * | 2020-01-17 | 2021-07-22 | London Health Sciences Centre Research Inc. | Planning and delivery of dynamically oriented electric field for biomedical applications |
| WO2021150877A1 (en) | 2020-01-22 | 2021-07-29 | Novocure Gmbh | Assemblies containing two conductive gel compositions and methods of production and use thereof |
| US20210299440A1 (en) | 2020-03-30 | 2021-09-30 | Novocure Gmbh | Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases |
| WO2021214693A1 (en) | 2020-04-24 | 2021-10-28 | Novocure Gmbh | Using alternating electric fields to increase permeability of the blood brain barrier |
| TW202537657A (zh) | 2020-05-06 | 2025-10-01 | 瑞士商諾沃庫勒有限責任公司 | 用於產生腫瘤治療電場之導電襯墊以及生產和使用其之方法 |
| KR102403686B1 (ko) * | 2020-05-15 | 2022-05-31 | 뉴로핏 주식회사 | 뇌자극 위치 제공장치 및 방법 |
| US11818943B2 (en) | 2020-06-25 | 2023-11-14 | Novocure Gmbh | Fabricating organic light emitting diodes (OLEDs) using tubulin |
| EP4223364B1 (en) | 2020-09-25 | 2024-04-24 | Novocure GmbH | Varying the metallization area on individual electrode elements in a tumor treating fields system to maximize current without overheating |
| TWI827889B (zh) * | 2020-10-16 | 2024-01-01 | 瑞士商諾沃庫勒有限責任公司 | 用於管理傳感器陣列佈置的方法和設備以及相關的非暫態的電腦可讀取的媒體 |
| WO2022175803A1 (en) | 2021-02-17 | 2022-08-25 | Novocure Gmbh | Arrays for delivering tumor treating fields (ttfields) with sets of electrode elements having individually adjustable active areas |
| WO2022190068A1 (en) | 2021-03-12 | 2022-09-15 | Novocure Gmbh | Methods of treating disease by skewing macrophage phenotype with alternating electric fields |
| JP2024513854A (ja) * | 2021-03-31 | 2024-03-27 | ノボキュア ゲーエムベーハー | 腫瘍治療電場(TTFields)システムの電極を使用したインピーダンス断層撮影法 |
| JP2024523598A (ja) | 2021-06-30 | 2024-06-28 | ノボキュア ゲーエムベーハー | 腫瘍治療電場(TTfields)を印加するためのトランスデューサアレイにおける電流を調整するためのキャパシタの使用 |
| WO2023084340A1 (en) * | 2021-11-12 | 2023-05-19 | Novocure Gmbh | Adjusting tumor treating fields simulation and treatment using molecular imaging |
| US12465780B2 (en) | 2021-11-12 | 2025-11-11 | Novocure Gmbh | Adjusting tumor treating fields simulation and treatment using molecular imaging |
| US20230168242A1 (en) | 2021-11-29 | 2023-06-01 | Novocure Gmbh | Methods of Reducing Ciliogenesis with Alternating Electric Fields |
| US12502548B2 (en) | 2021-12-29 | 2025-12-23 | Novocure Gmbh | Reducing electrosensation whilst treating a subject using alternating electric fields by using larger cathodes and smaller anodes |
| JP2024545019A (ja) | 2021-12-30 | 2024-12-05 | ノボキュア ゲーエムベーハー | 腫瘍治療フィールド(ttfield)を使用した治療のためのパラメータ値の選択 |
| CA3255022A1 (en) | 2022-03-30 | 2023-10-05 | Novocure Gmbh | USE OF INTERLACED COOLING PERIODS TO INCREASE THE MAXIMUM INTENSITY OF TUMOR TREATMENT FIELDS |
| CN119013076A (zh) | 2022-03-30 | 2024-11-22 | 诺沃库勒有限责任公司 | 通过将换能器阵列配对在一起来使用交流电场治疗受试者的同时减少电敏 |
| WO2023242741A1 (en) | 2022-06-13 | 2023-12-21 | Novocure Gmbh | Systems and methods for increasing intestinal absorption of therapeutic agents |
| JP2025520608A (ja) | 2022-06-20 | 2025-07-03 | ノボキュア ゲーエムベーハー | 癌を治療するための組成物、システム、および方法、腫瘍治療場およびvegf阻害剤 |
| JP2025520663A (ja) | 2022-06-21 | 2025-07-03 | ノボキュア ゲーエムベーハー | 交流電場とcrispr-casシステムを用いた症状および疾患の治療システムおよび方法 |
| CN119968209A (zh) | 2022-09-30 | 2025-05-09 | 诺沃库勒有限责任公司 | 使用交变电场和树突状细胞治疗癌症的组合物、系统和方法 |
| JP2025532048A (ja) | 2022-09-30 | 2025-09-29 | ノボキュア ゲーエムベーハー | 交流電場およびアポトーシスがん細胞ワクチンを用いたがん治療のための組成物、システムおよび方法 |
| CN119968221A (zh) | 2022-09-30 | 2025-05-09 | 诺沃库勒有限责任公司 | 用于减少电感应和/或皮肤刺激的组合物、系统和方法 |
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2019
- 2019-04-09 PL PL19725401.4T patent/PL3775956T3/pl unknown
- 2019-04-09 WO PCT/IB2019/052931 patent/WO2019197999A1/en not_active Ceased
- 2019-04-09 US US16/378,826 patent/US11650277B2/en active Active
- 2019-04-09 EP EP21150622.5A patent/EP3832335A1/en active Pending
- 2019-04-09 KR KR1020207032108A patent/KR102687814B1/ko active Active
- 2019-04-09 EP EP19725401.4A patent/EP3775956B1/en active Active
- 2019-04-09 JP JP2021504591A patent/JP7225373B2/ja active Active
- 2019-04-09 CN CN201980038700.0A patent/CN112424626B/zh active Active
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| US11650277B2 (en) | 2023-05-16 |
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| CN112424626B (zh) | 2025-07-08 |
| CN112424626A (zh) | 2021-02-26 |
| KR102687814B1 (ko) | 2024-07-24 |
| US20190308016A1 (en) | 2019-10-10 |
| JP7225373B2 (ja) | 2023-02-20 |
| JP2021520970A (ja) | 2021-08-26 |
| EP3775956A1 (en) | 2021-02-17 |
| KR20200141478A (ko) | 2020-12-18 |
| CA3096429C (en) | 2023-10-17 |
| CA3096429A1 (en) | 2019-10-17 |
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